Preemptive therapy for genetic disease

Nature Medicine

Volumn 2, Issue 2, 1996, Pages 161-162

  Anthony Blau, C ^a   Stamatoyannopoulos, George ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD DISEASE; CELL TRANSPLANTATION; FETUS DISEASE; GENETIC DISORDER; HUMAN; PRIORITY JOURNAL; SHORT SURVEY; STEM CELL;

BLOOD TRANSFUSION, INTRAUTERINE; FEMALE; HEMATOLOGIC DISEASES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; PREGNANCY; PRENATAL DIAGNOSIS;

EID: 19144370682     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0296-161     Document Type: Short Survey

References (7)

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2. Buckley, R.H. et al. Development of immunity in human severe primary T cell deficiency following haploidentical bone marrow stem cell transplantation. J. Immunol. 136, 2398-2407 (1986).
3. Noguchi, M. et al. Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans. Cell 73, 147-157 (1993).
4. Cowan, M.J. and Globus, M. In utero hematopoietic stem cell transplants for inherited diseases. Am. J. Pediat. Hematol./Oncol. 16, 35-42 (1994).
5. Nesci, S. et al. Mixed chimerism in thalassemic patients after bone marrow transplantation. B.M.T. 10, 143-146 (1992).
6. Kapelushnik, J. et al. Analysis of β-globin mutations shows stable mixed chimerism in patients with thalassemia after bone marrow transplantation. Blood 86, 3241-3246 (1995).
7. Lucarelli, G. et al. Marrow transplantation in patients with thalassemia responsive to chelation therapy N. Engl. J. Med. 329, 840-844 (1993).