-
1
-
-
0023484475
-
The risks and benefits of clozapine versus chloropromazine
-
J. Claghorn, G. Honigfeld, F. S. Abuzzahab, Sr., R. Wang, R. Steinbook, V. Tuason, and G. Klerman: The risks and benefits of clozapine versus chloropromazine. J. Clin. Psychopharmacol 7, 377-384 (1987).
-
(1987)
J. Clin. Psychopharmacol
, vol.7
, pp. 377-384
-
-
Claghorn, J.1
Honigfeld, G.2
Abuzzahab Sr., F.S.3
Wang, R.4
Steinbook, R.5
Tuason, V.6
Klerman, G.7
-
2
-
-
0023812652
-
Clozapine for the treatment-resistant schizophrenic
-
J. Kane, G. Honigfeld, J. Singer, H. Meltzer, and the Clozaril Collaborative Study Group: Clozapine for the treatment-resistant schizophrenic. Arch. Gen. Psychiatry 45, 789-796 (1988).
-
(1988)
Arch. Gen. Psychiatry
, vol.45
, pp. 789-796
-
-
Kane, J.1
Honigfeld, G.2
Singer, J.3
Meltzer, H.4
-
3
-
-
0026482396
-
Determination of clozapine and its major metabolites in human serum using automated solid-phase extraction and subsequent isocratic high-performance liquid chromatography with ultraviolet detection
-
H. Weigmann and C. Hiemke: Determination of clozapine and its major metabolites in human serum using automated solid-phase extraction and subsequent isocratic high-performance liquid chromatography with ultraviolet detection. J. Chromatogr. 583, 209-216 (1992).
-
(1992)
J. Chromatogr.
, vol.583
, pp. 209-216
-
-
Weigmann, H.1
Hiemke, C.2
-
4
-
-
0027393926
-
Determination of clozapine and desmethylclozapine in human plasma by high-performance liquid chromatography with ultraviolet detection
-
M.-C. Chung, S.-K. Lin, W.-H. Chang, M. W. Jann: Determination of clozapine and desmethylclozapine in human plasma by high-performance liquid chromatography with ultraviolet detection. J. Chromatogr. 613, 168-173 (1993).
-
(1993)
J. Chromatogr.
, vol.613
, pp. 168-173
-
-
Chung, M.-C.1
Lin, S.-K.2
Chang, W.-H.3
Jann, M.W.4
-
5
-
-
0027740188
-
Relationship between clinical efficacy and clozapine concentrations in plasma in schizophrenia: Effect of smoking
-
M. Hasegawa, R. Gutierrez-Esteinou, L. Way, and H. Y. Meltzer: Relationship between clinical efficacy and clozapine concentrations in plasma in schizophrenia: effect of smoking. J. Clin. Pharmacol. 13, 383-390 (1993).
-
(1993)
J. Clin. Pharmacol.
, vol.13
, pp. 383-390
-
-
Hasegawa, M.1
Gutierrez-Esteinou, R.2
Way, L.3
Meltzer, H.Y.4
-
6
-
-
0027218389
-
Determination of clozapine, norclozapine, and clozapine N-oxide in serum by liquid chromatography
-
S. A. Volpicelli, F. Centorrino, P. R. Puopolo, J. Kando, F. R. Frankenburg, R. J. Baldessarini, and J. G. Flood: Determination of clozapine, norclozapine, and clozapine N-oxide in serum by liquid chromatography. Clin. Chem. 39, 1656-1659 (1993).
-
(1993)
Clin. Chem.
, vol.39
, pp. 1656-1659
-
-
Volpicelli, S.A.1
Centorrino, F.2
Puopolo, P.R.3
Kando, J.4
Frankenburg, F.R.5
Baldessarini, R.J.6
Flood, J.G.7
-
7
-
-
0028270373
-
Disposition of clozapine and desmethylclozapine in schizophrenic patients
-
S.-K. Lin, W.-H. Chang, M.-C. Chung, Y. W. F. Lam, and M. W. Jann: Disposition of clozapine and desmethylclozapine in schizophrenic patients. J. Clin. Pharmacol. 34, 318-324 (1994).
-
(1994)
J. Clin. Pharmacol.
, vol.34
, pp. 318-324
-
-
Lin, S.-K.1
Chang, W.-H.2
Chung, M.-C.3
Lam, Y.W.F.4
Jann, M.W.5
-
8
-
-
0028324887
-
Clozapine and metabolites: Concentrations in serum and clinical findings during treatment of chronically psychotic patients
-
F. Centorrino, R. J. Baldessarini, J. C. Kando, F. R. Frankenburg, S. A. Volpicelli, and J. G. Flood: Clozapine and metabolites: concentrations in serum and clinical findings during treatment of chronically psychotic patients. J. Clin. Psychopharmacol. 14, 119-125 (1994).
-
(1994)
J. Clin. Psychopharmacol.
, vol.14
, pp. 119-125
-
-
Centorrino, F.1
Baldessarini, R.J.2
Kando, J.C.3
Frankenburg, F.R.4
Volpicelli, S.A.5
Flood, J.G.6
-
9
-
-
0015154377
-
The metabolism of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine (clozapine) in mice, dogs, and human subjects
-
R. Gauch and W. Michaelis: The metabolism of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine (clozapine) in mice, dogs, and human subjects. Il Farmaco-Ed. Pr. 26, 667-681 (1970).
-
(1970)
Il Farmaco-Ed. Pr.
, vol.26
, pp. 667-681
-
-
Gauch, R.1
Michaelis, W.2
-
10
-
-
0028588470
-
Rapid formation of clozapine in guinea-pigs and man following clozapine-N-oxide administration
-
M. W. Jann, Y. W. F. Lam, and W.-H. Chang: Rapid formation of clozapine in guinea-pigs and man following clozapine-N-oxide administration. Arch. Int. Pharmacodyn. 328, 243-250 (1994).
-
(1994)
Arch. Int. Pharmacodyn.
, vol.328
, pp. 243-250
-
-
Jann, M.W.1
Lam, Y.W.F.2
Chang, W.-H.3
-
12
-
-
85081422458
-
Application of ESI-MS to the identification of new metabolites of clozapine
-
May 29-June 3
-
G. McKay, G-Q. Zhang, N. Pidskalny, and K. K. Midha: Application of ESI-MS to the identification of new metabolites of clozapine. In "Proceedings the 42nd ASMS Conference on Mass Spectrometry and Allied Topics," May 29-June 3, 1994, p. 346.
-
(1994)
Proceedings the 42nd ASMS Conference on Mass Spectrometry and Allied Topics
, pp. 346
-
-
McKay, G.1
Zhang, G.-Q.2
Pidskalny, N.3
Midha, K.K.4
-
13
-
-
0028174217
-
+-glucuronide in the urine of patients treated with clozapine using electrospray mass spectrometry
-
+-glucuronide in the urine of patients treated with clozapine using electrospray mass spectrometry. Biol. Mass Spectrom. 23, 147-148 (1994).
-
(1994)
Biol. Mass Spectrom.
, vol.23
, pp. 147-148
-
-
Luo, H.1
McKay, G.2
Midha, K.K.3
-
14
-
-
0025032064
-
Single- vs multiple-dose pharmacokinetics of clozapine in psychiatric patients
-
M. G. Choc, F. Hsuan, G. Honigfeld, W. T. Robinson, L. Ereshefsky, M. L. Crismon, S. R. Saklad, J. Hirschowitz, and R. Wagner: Single-vs multiple-dose pharmacokinetics of clozapine in psychiatric patients. Pharm. Res. 7, 347-351 (1990).
-
(1990)
Pharm. Res.
, vol.7
, pp. 347-351
-
-
Choc, M.G.1
Hsuan, F.2
Honigfeld, G.3
Robinson, W.T.4
Ereshefsky, L.5
Crismon, M.L.6
Saklad, S.R.7
Hirschowitz, J.8
Wagner, R.9
-
15
-
-
0023475155
-
Multiple-dose pharmacokinetics of clozapine in patients
-
M. G. Choc, R. G. Lehr, F. Hsuan, G. Honigfeld, H. T. Smith, R. Borison, and J. Volavka: Multiple-dose pharmacokinetics of clozapine in patients. Pharm. Res. 4, 402-405 (1987).
-
(1987)
Pharm. Res.
, vol.4
, pp. 402-405
-
-
Choc, M.G.1
Lehr, R.G.2
Hsuan, F.3
Honigfeld, G.4
Smith, H.T.5
Borison, R.6
Volavka, J.7
-
16
-
-
0022527145
-
Bioavailability of psychotropic drugs: Historical perspective and pharmacokinetics overview
-
L. Ereshefsky, M. W. Jann, S. R. Saklad, and C. M. Davis: Bioavailability of psychotropic drugs: historical perspective and pharmacokinetics overview. J. Clin. Psychiatry 47, (Suppl. 9) 6-15 (1986).
-
(1986)
J. Clin. Psychiatry
, vol.47
, Issue.9 SUPPL.
, pp. 6-15
-
-
Ereshefsky, L.1
Jann, M.W.2
Saklad, S.R.3
Davis, C.M.4
-
17
-
-
0030012851
-
Application of electrospray mass spectrometry to the identification of intact glucuronide and sulphate conjugates of clozapine in the rat
-
G.-Q. Zhang, G. McKay, J. W. Hubbard, and K. K. Midha: Application of electrospray mass spectrometry to the identification of intact glucuronide and sulphate conjugates of clozapine in the rat. Xenobiotica 26, 541-550 (1996).
-
(1996)
Xenobiotica
, vol.26
, pp. 541-550
-
-
Zhang, G.-Q.1
McKay, G.2
Hubbard, J.W.3
Midha, K.K.4
-
19
-
-
0030048621
-
Pharmacokinetics, absolute bioavailability, and disposition of [14C]nefazodone in humans
-
R. M. Barbhaiya, K. A. Dandekar, and D. S. Greene: Pharmacokinetics, absolute bioavailability, and disposition of [14C]nefazodone in humans. Drug Metab. Dispos. 24, 91-95 (1996).
-
(1996)
Drug Metab. Dispos.
, vol.24
, pp. 91-95
-
-
Barbhaiya, R.M.1
Dandekar, K.A.2
Greene, D.S.3
-
20
-
-
0027406654
-
Fluvoxamine is a potent inhibitor of cytochrome P4501A2
-
K. Brøsen, E. Skjelbo, B. B. Rasmussen, H. E. Poulsen, and S. Loft: Fluvoxamine is a potent inhibitor of cytochrome P4501A2. Biochem. Pharmacol. 45, 1211-1214 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 1211-1214
-
-
Brøsen, K.1
Skjelbo, E.2
Rasmussen, B.B.3
Poulsen, H.E.4
Loft, S.5
-
21
-
-
0028318482
-
Fluvoxamine inhibition and carbemazepine induction of the metabolism of clozapine: Evidence from a therapeutic drug monitoring service
-
M. Jerling, L. Lindström, U. Bondesson, L. Bertilsson: Fluvoxamine inhibition and carbemazepine induction of the metabolism of clozapine: evidence from a therapeutic drug monitoring service. Ther. Drug Monit. 16, 368-374 (1994).
-
(1994)
Ther. Drug Monit.
, vol.16
, pp. 368-374
-
-
Jerling, M.1
Lindström, L.2
Bondesson, U.3
Bertilsson, L.4
-
22
-
-
0028016505
-
Elevated levels of clozapine in serum after addition of fluvoxamine
-
C. Hiemke, H. Weigmann, S. Härtter, N. Dahmen, H. Wetzel, and H. Müller: Elevated levels of clozapine in serum after addition of fluvoxamine. J. Clin. Psychopharmacol. 14, 279-281 (1995).
-
(1995)
J. Clin. Psychopharmacol.
, vol.14
, pp. 279-281
-
-
Hiemke, C.1
Weigmann, H.2
Härtter, S.3
Dahmen, N.4
Wetzel, H.5
Müller, H.6
-
23
-
-
0027985726
-
Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test
-
L. Bertilsson, J. A. Carrillo, M-L Dahl, A. Llerena, C. Alm, U. Bondesson, L. Lindström, I. R. De La Rubia, S. Ramos, and J. Benitez: Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test. Br. J. Clin. Pharmacol. 38, 471-473 (1994).
-
(1994)
Br. J. Clin. Pharmacol.
, vol.38
, pp. 471-473
-
-
Bertilsson, L.1
Carrillo, J.A.2
Dahl, M.-L.3
Llerena, A.4
Alm, C.5
Bondesson, U.6
Lindström, L.7
De La Rubia, I.R.8
Ramos, S.9
Benitez, J.10
-
24
-
-
0028902662
-
Cytochrome P4502D6 genotype does not determine response to clozapine
-
M. J. Arranz, E. Dawson, S. Shaikh, P. Sham, T. Sharma, K. Aitchison, M. A. Crocq, M. Gill, R. Kerwin, and D. A. Collier: Cytochrome P4502D6 genotype does not determine response to clozapine. Br. J. Clin. Pharamcol. 38, 417-420 (1994).
-
(1994)
Br. J. Clin. Pharamcol.
, vol.38
, pp. 417-420
-
-
Arranz, M.J.1
Dawson, E.2
Shaikh, S.3
Sham, P.4
Sharma, T.5
Aitchison, K.6
Crocq, M.A.7
Gill, M.8
Kerwin, R.9
Collier, D.A.10
-
25
-
-
0028307888
-
Disposition of clozapine in man: Lack of association with debrisoquine and S-mephenytoin hydroxylation polymorphisms
-
M-L Dahl, A. Llerna, U. Bondesson, L. Lindström, and L. Bertilsson: Disposition of clozapine in man: lack of association with debrisoquine and S-mephenytoin hydroxylation polymorphisms. Br. J. Clin. Pharmacol. 37, 71-74 (1994).
-
(1994)
Br. J. Clin. Pharmacol.
, vol.37
, pp. 71-74
-
-
Dahl, M.-L.1
Llerna, A.2
Bondesson, U.3
Lindström, L.4
Bertilsson, L.5
-
26
-
-
0028944753
-
Metabolism and bioactivation of clozapine by human liver in vitro
-
M. Pirmohamed, D. Williams, S. Madden, E. Templeton, and B. K. Park: Metabolism and bioactivation of clozapine by human liver in vitro. J. Pharmacol. Exp. Ther. 272, 984-990 (1995).
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.272
, pp. 984-990
-
-
Pirmohamed, M.1
Williams, D.2
Madden, S.3
Templeton, E.4
Park, B.K.5
-
27
-
-
0028052932
-
Serum concentrations of clozapine and its major metabolites: Effects of cotreatment with fluoxetine or valproate
-
F. Centorrino, R. J. Baldessarini, J. Kando, F. R. Frankenburg, S. A. Volpicelli, P. R. Puopolo, and J. G. Flood: Serum concentrations of clozapine and its major metabolites: effects of cotreatment with fluoxetine or valproate. Am. J. Psychiatry 151, 123-125 (1994).
-
(1994)
Am. J. Psychiatry
, vol.151
, pp. 123-125
-
-
Centorrino, F.1
Baldessarini, R.J.2
Kando, J.3
Frankenburg, F.R.4
Volpicelli, S.A.5
Puopolo, P.R.6
Flood, J.G.7
-
28
-
-
0026011475
-
A case report of cimetidine-induced clozapine toxicity
-
S. Syzmanski, J. A. Lieberman, D. Picou, S. Masiar, and T. Cooper: A case report of cimetidine-induced clozapine toxicity. J. Clin. Psychiatry 52, 21-22 (1991).
-
(1991)
J. Clin. Psychiatry
, vol.52
, pp. 21-22
-
-
Syzmanski, S.1
Lieberman, J.A.2
Picou, D.3
Masiar, S.4
Cooper, T.5
-
30
-
-
0026078295
-
Effect of phenytoin on plasma clozapine concentrations in two patients
-
D. D. Miller: Effect of phenytoin on plasma clozapine concentrations in two patients. J. Clin. Psychiatry 52, 23-25 (1991).
-
(1991)
J. Clin. Psychiatry
, vol.52
, pp. 23-25
-
-
Miller, D.D.1
-
31
-
-
0028071665
-
Normal volunteers should not be used for bioavailability or bioequivalence studies of clozapine
-
R. Pokorny, M. J. Finkel, and W. T. Robinson: Normal volunteers should not be used for bioavailability or bioequivalence studies of clozapine. Pharm. Res. 11, 1221 (1994).
-
(1994)
Pharm. Res.
, vol.11
, pp. 1221
-
-
Pokorny, R.1
Finkel, M.J.2
Robinson, W.T.3
-
32
-
-
0013482978
-
-
F-D-C Reports, Inc., Chevy Chase, MD
-
F-D-C Reports, F-D-C Reports, Inc., pp. T&G-6 to T&G-7; Chevy Chase, MD (1995).
-
(1995)
F-D-C Reports
-
-
|