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Volumn 26, Issue 5, 1996, Pages 541-550

Application of electrospray mass spectrometry in the identification of intact glucuronide and sulphate conjugates of clozapine in rat

Author keywords

[No Author keywords available]

Indexed keywords

7 GLUCURONYLOXYCLOZAPINE; CLOZAPINE; DRUG METABOLITE; GLUCURONIDE; NORCLOZAPINE; SULFATE; UNCLASSIFIED DRUG;

EID: 0030012851     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.3109/00498259609046730     Document Type: Article
Times cited : (18)

References (12)
  • 1
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    • Possible role of free radical formation in clozapine (Clozaril)-induced agranulocytosis
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    • (1991) Molecular Pharmacology , vol.40 , pp. 846-853
    • Fischer, V.1    Haar, J.2    Greiner, L.3    Lloyd, R.4    Mason, R.5
  • 2
    • 0025599851 scopus 로고
    • Clozapine: A review of its pharmacological properties and therapeutic use in the treatment of schizophrenia
    • FITTON, A., and HELL, R., 1990, Clozapine: a review of its pharmacological properties and therapeutic use in the treatment of schizophrenia. Drugs, 40, 722-747.
    • (1990) Drugs , vol.40 , pp. 722-747
    • Fitton, A.1    Hell, R.2
  • 3
    • 0015154377 scopus 로고
    • The metabolism of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine (clozapine) in mice, dogs and human subjects
    • GAUCH, R., and MICHAELIS, W., 1971, The metabolism of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine (clozapine) in mice, dogs and human subjects. Farmaco, 26, 667-681.
    • (1971) Farmaco , vol.26 , pp. 667-681
    • Gauch, R.1    Michaelis, W.2
  • 4
    • 0344043698 scopus 로고
    • Mechanisms of clozapine induced agranulocytosis
    • GERSON, S., and MELTZER, H., 1992, Mechanisms of clozapine induced agranulocytosis. Drug Safety, 7 (suppl. 1), 17-25.
    • (1992) Drug Safety , vol.7 , Issue.1 SUPPL. , pp. 17-25
    • Gerson, S.1    Meltzer, H.2
  • 5
    • 0023812652 scopus 로고
    • Clozapine for the treatment resistant schizophrenic. A double blind comparison with chlorpromazine/benztropine
    • KANE, J., HONIGFELD, G., SINGER, J., and MELTZER, H., 1988, Clozapine for the treatment resistant schizophrenic. A double blind comparison with chlorpromazine/benztropine. Archives of General Psychiatry, 45, 789-796.
    • (1988) Archives of General Psychiatry , vol.45 , pp. 789-796
    • Kane, J.1    Honigfeld, G.2    Singer, J.3    Meltzer, H.4
  • 8
    • 0026493448 scopus 로고
    • Possible role of free radical formation in drug-induced agranulocytosis
    • MASON, R., and FISCHER, V., 1992, Possible role of free radical formation in drug-induced agranulocytosis. Drug Safety, 7 (suppl. 1), 45-50.
    • (1992) Drug Safety , vol.7 , Issue.1 SUPPL. , pp. 45-50
    • Mason, R.1    Fischer, V.2
  • 9
    • 0024443178 scopus 로고
    • A prospective study of clozapine in treatment-resistant schizophrenic patients. I. Preliminary report
    • MELTZER, H., BASTANI, B., YOUNG KWON, K., RAMIREZ, L., BURNET, S., and SHARPE, J., 1989, A prospective study of clozapine in treatment-resistant schizophrenic patients. I. Preliminary report. Psychopharmacology, 99, S68-72.
    • (1989) Psychopharmacology , vol.99
    • Meltzer, H.1    Bastani, B.2    Young Kwon, K.3    Ramirez, L.4    Burnet, S.5    Sharpe, J.6
  • 10
    • 0019738070 scopus 로고
    • Collection of metabolites from bile and urine from the rat
    • MULDER, G. SCHOLTENS, E., and MEIJER, D., 1981, Collection of metabolites from bile and urine from the rat. Methods in Enzymology, 77, 21-30.
    • (1981) Methods in Enzymology , vol.77 , pp. 21-30
    • Mulder, G.1    Scholtens, E.2    Meijer, D.3
  • 11
    • 0013677025 scopus 로고
    • Metabolism of clozapine by neutrophils. Possible implications for clozapine-induced agranulocytosis
    • UTRECHT, J., 1992, Metabolism of clozapine by neutrophils. Possible implications for clozapine-induced agranulocytosis. Drug Safety, 7 (suppl. 1), 51-56.
    • (1992) Drug Safety , vol.7 , Issue.1 SUPPL. , pp. 51-56
    • Utrecht, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.