Intestinal transport and metabolism of analgesic dipeptide, kyotorphin: Rate-limiting factor in intestinal absorption of peptide as drug

Biochimica et Biophysica Acta - General Subjects

Volumn 1335, Issue 1-2, 1997, Pages 111-119

  Mizuma, Takashi ^a   Koyanagi, Akihiro ^a   Awazu, Shoji ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Intestinal absorption; Kinetic analysis; Kyotorphin; Metabolism; Peptide absorption; Rat intestine; Transport

Indexed keywords

KYOTORPHIN; PEPTIDE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DEGRADATION; DRUG METABOLISM; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE ABSORPTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REGIONAL PERFUSION;

ANALGESICS; ANIMALS; BIOLOGICAL TRANSPORT; ENDORPHINS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; INTESTINE, SMALL; LEUCINE; METABOLIC CLEARANCE RATE; PHENANTHROLINES; PROTEASE INHIBITORS; RATS; TRYPTOPHAN;

ANIMALIA;

EID: 0030951623     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-4165(96)00128-6     Document Type: Article

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