-
1
-
-
0025324321
-
Drug susceptibilities of isolates of varicella-zoster virus in a clinical study of oral brovavir
-
Machida H, Nishitani M. Drug susceptibilities of isolates of varicella-zoster virus in a clinical study of oral brovavir. Microbiol Immunol 1990;34:407-11.
-
(1990)
Microbiol Immunol
, vol.34
, pp. 407-411
-
-
Machida, H.1
Nishitani, M.2
-
2
-
-
0023681805
-
Effects of various nucleosides on antiviral activity and metabolism of 1-beta-D-arabinofuranosoyl-E-5 (2-bromovinyl) uracil against herpes virus types 1 and 2
-
Suzatani T, Machida H, Sakuma T, Azuma M. Effects of various nucleosides on antiviral activity and metabolism of 1-beta-D-arabinofuranosoyl-E-5 (2-bromovinyl) uracil against herpes virus types 1 and 2. Antimicrob Agents Chemother 1988;32:1547-51.
-
(1988)
Antimicrob Agents Chemother
, vol.32
, pp. 1547-1551
-
-
Suzatani, T.1
Machida, H.2
Sakuma, T.3
Azuma, M.4
-
3
-
-
0023681107
-
Comparison of two bromovinyl nucleoside analogs, 1-beta-D-arabinofurasnosyl-E-5 (2-bromovinyl) uracil and E-5 (2-bromovinyl)-2-deoxyuridine, with acyclovir in inhibition of Epstein-Barr virus replication
-
Lin JC, Machida H. Comparison of two bromovinyl nucleoside analogs, 1-beta-D-arabinofurasnosyl-E-5 (2-bromovinyl) uracil and E-5 (2-bromovinyl)-2-deoxyuridine, with acyclovir in inhibition of Epstein-Barr virus replication. Antimcicrob Agents Chemother 1988;32:1068-107.
-
(1988)
Antimcicrob Agents Chemother
, vol.32
, pp. 1068-1107
-
-
Lin, J.C.1
Machida, H.2
-
4
-
-
0029553816
-
Sorivudine: A promising drug for the treatment of varicella-zoster virus infection
-
Whitley RJ. Sorivudine: a promising drug for the treatment of varicella-zoster virus infection. Neurology 1995;45:S73-5.
-
(1995)
Neurology
, vol.45
-
-
Whitley, R.J.1
-
5
-
-
0028488847
-
Prevention of drug interactions and its countermeasure
-
Nakamura H, Omori S, Kitada K, Mochida A. Prevention of drug interactions and its countermeasure [Japanese]. J Toxicol Sci 1994;19:89-93.
-
(1994)
J Toxicol Sci
, vol.19
, pp. 89-93
-
-
Nakamura, H.1
Omori, S.2
Kitada, K.3
Mochida, A.4
-
6
-
-
0022550597
-
Effect of E-5-(2-bromovinyl)-uracil on the catabolism and antitumor activity of 5-fluorouracil in rats and leukemic mice
-
Desgranges C, Razaka G, DeClerq E. Effect of E-5-(2-bromovinyl)-uracil on the catabolism and antitumor activity of 5-fluorouracil in rats and leukemic mice. Cancer Res 1986;46:1094-101.
-
(1986)
Cancer Res
, vol.46
, pp. 1094-1101
-
-
Desgranges, C.1
Razaka, G.2
DeClerq, E.3
-
7
-
-
0024595925
-
Clinical pharmacology of 5-fluorouracil
-
Diasio RB, Harris BE. Clinical pharmacology of 5-fluorouracil. Clin Pharmacokinet 1989;16:215-37.
-
(1989)
Clin Pharmacokinet
, vol.16
, pp. 215-237
-
-
Diasio, R.B.1
Harris, B.E.2
-
8
-
-
0023187085
-
Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine and bile
-
Heggie GD, Sommadossi JP, Cross DS, Huster WJ, Diasio RB. Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine and bile. Cancer Res 1987;47:2203-6.
-
(1987)
Cancer Res
, vol.47
, pp. 2203-2206
-
-
Heggie, G.D.1
Sommadossi, J.P.2
Cross, D.S.3
Huster, W.J.4
Diasio, R.B.5
-
9
-
-
0023902287
-
Familial deficiency of dihydropyrimidine dehydrogenase: Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity
-
Diasio RB, Beavers TL, Carpenter JT. Familial deficiency of dihydropyrimidine dehydrogenase: biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity. J Clin Invest 1988;81: 47-51.
-
(1988)
J Clin Invest
, vol.81
, pp. 47-51
-
-
Diasio, R.B.1
Beavers, T.L.2
Carpenter, J.T.3
-
10
-
-
0022263834
-
Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity
-
Tuchman M, Stoeckeler JS, Kiang DT, O'Dea RF, Ramnaraine ML, Mirkin BL. Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity. N Engl J Med 1985;313:245-9.
-
(1985)
N Engl J Med
, vol.313
, pp. 245-249
-
-
Tuchman, M.1
Stoeckeler, J.S.2
Kiang, D.T.3
O'Dea, R.F.4
Ramnaraine, M.L.5
Mirkin, B.L.6
-
11
-
-
0025990479
-
Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency: A potentially more common pharmacogenetic syndrome
-
Harris BE, Carpenter JT, Diasio RB. Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency: a potentially more common pharmacogenetic syndrome. Cancer 1991;68: 499-501.
-
(1991)
Cancer
, vol.68
, pp. 499-501
-
-
Harris, B.E.1
Carpenter, J.T.2
Diasio, R.B.3
-
12
-
-
12644319857
-
Severe 5-fluorouracil toxicity in a patient with decreased dihydropyrimidine dehydrogenase activity
-
Lyss AP, Lilenbaum RC, Harris BE, Diasio RB. Severe 5-fluorouracil toxicity in a patient with decreased dihydropyrimidine dehydrogenase activity. Cancer Invest 1993;53:5433-8.
-
(1993)
Cancer Invest
, vol.53
, pp. 5433-5438
-
-
Lyss, A.P.1
Lilenbaum, R.C.2
Harris, B.E.3
Diasio, R.B.4
-
13
-
-
0027426408
-
Dihydropyrimidine dehydrogenase activity in peripheral blood mononuclear cells and liver: Population characteristics, newly identified deficiency patients, and clinical implication in 5-fluorouracil chemotherapy
-
Lu Z, Zhang R, Diasio RB. Dihydropyrimidine dehydrogenase activity in peripheral blood mononuclear cells and liver: population characteristics, newly identified deficiency patients, and clinical implication in 5-fluorouracil chemotherapy. Cancer Res 1993;53: 5433-8.
-
(1993)
Cancer Res
, vol.53
, pp. 5433-5438
-
-
Lu, Z.1
Zhang, R.2
Diasio, R.B.3
-
14
-
-
0027496582
-
Severe fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency
-
Houyan P, Gay C, Chatelut E, Canal P, Milano G. Severe fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency. J Natl Cancer Inst 1993;85:1602-3.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1602-1603
-
-
Houyan, P.1
Gay, C.2
Chatelut, E.3
Canal, P.4
Milano, G.5
-
15
-
-
0023883431
-
Enhancing effect of bromovinyluracil on antitumour activity of 5-fluorouracil against adenocarcinoma 755 in mice: Increased therapeutic index and correlation with increased plasma 5-fluorouracil levels
-
Iigo M, Araki E, Nakajima Y, Hoshi A, DeClerq E. Enhancing effect of bromovinyluracil on antitumour activity of 5-fluorouracil against adenocarcinoma 755 in mice: increased therapeutic index and correlation with increased plasma 5-fluorouracil levels. Biochem Pharmacol 1988;37:1609-13.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 1609-1613
-
-
Iigo, M.1
Araki, E.2
Nakajima, Y.3
Hoshi, A.4
DeClerq, E.5
-
16
-
-
0022975956
-
Enhancing effect of bromovinyluracil on antitumour activity of 5-fluorouracil in mice bearing MOPC-315 plasmacytomas
-
Ben-Efraim S, Shoval S, DeClerq E. Enhancing effect of bromovinyluracil on antitumour activity of 5-fluorouracil in mice bearing MOPC-315 plasmacytomas. Br J Cancer 1986;54:847-51.
-
(1986)
Br J Cancer
, vol.54
, pp. 847-851
-
-
Ben-Efraim, S.1
Shoval, S.2
DeClerq, E.3
-
17
-
-
0030005786
-
Link between dihydropyrimidine dehydrogenase activity in peripheral blood mononuclear cells and liver
-
Chazal M, Etienne MC, Renee N, Bourgeon A, Richelme H, Milano G. Link between dihydropyrimidine dehydrogenase activity in peripheral blood mononuclear cells and liver. Clin Cancer Res 1996;2:507-10.
-
(1996)
Clin Cancer Res
, vol.2
, pp. 507-510
-
-
Chazal, M.1
Etienne, M.C.2
Renee, N.3
Bourgeon, A.4
Richelme, H.5
Milano, G.6
-
18
-
-
0025058867
-
Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion
-
Harris BE, Song S, Soong S, Diasio RB. Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion. Cancer Res 1990;50:197-201.
-
(1990)
Cancer Res
, vol.50
, pp. 197-201
-
-
Harris, B.E.1
Song, S.2
Soong, S.3
Diasio, R.B.4
-
19
-
-
0017184389
-
A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
20
-
-
0020451764
-
Rapid catabolism of 5-fluorouracil in freshly isolated hepatocytes as analyzed by high performance liquid chromatography
-
Sommadossi JP, Gewirtz DA, Diasio RB, Aubert C, Cano JP, Goldman ID. Rapid catabolism of 5-fluorouracil in freshly isolated hepatocytes as analyzed by high performance liquid chromatography. J Biol Chem 1982;257:8171-6.
-
(1982)
J Biol Chem
, vol.257
, pp. 8171-8176
-
-
Sommadossi, J.P.1
Gewirtz, D.A.2
Diasio, R.B.3
Aubert, C.4
Cano, J.P.5
Goldman, I.D.6
-
21
-
-
0027534425
-
Dihydropyrimidine dehydrogenase activity in cancer patients
-
Fleming RA, Milano GA, Gaspard MH, Bargnoux PJ, Thyss A, Plagne P, et al. Dihydropyrimidine dehydrogenase activity in cancer patients. Eur J Cancer 1993; 29A:740-4.
-
(1993)
Eur J Cancer
, vol.29 A
, pp. 740-744
-
-
Fleming, R.A.1
Milano, G.A.2
Gaspard, M.H.3
Bargnoux, P.J.4
Thyss, A.5
Plagne, P.6
-
22
-
-
0022519074
-
Dihydropyrimidine dehydrogenase deficiency in a family, leading to elevated levels of uracil and thymine
-
De Abreu RA, Bakkeren JA, Braakhekke J, Gabreels FJ, Mass JM Sengers RC. Dihydropyrimidine dehydrogenase deficiency in a family, leading to elevated levels of uracil and thymine. Adv Exp Med Biol 1986; 195A:71-6.
-
(1986)
Adv Exp Med Biol
, vol.195 A
, pp. 71-76
-
-
De Abreu, R.A.1
Bakkeren, J.A.2
Braakhekke, J.3
Gabreels, F.J.4
Mass, J.M.5
Sengers, R.C.6
-
23
-
-
0342833351
-
A phase I pharmacokinetics study of 5-ethynyluracil plus 5-fluorouracil in cancer patients with solid tumors
-
Khor SP, Lucas S, Schilsky R, Burris H, Von Hoff DD, Zhang R, et al. A phase I pharmacokinetics study of 5-ethynyluracil plus 5-fluorouracil in cancer patients with solid tumors [abstract]. Proc Am Assoc Cancer Res 1995;36:1439.
-
(1995)
Proc Am Assoc Cancer Res
, vol.36
, pp. 1439
-
-
Khor, S.P.1
Lucas, S.2
Schilsky, R.3
Burris, H.4
Von Hoff, D.D.5
Zhang, R.6
-
24
-
-
0030067723
-
Inhibition of dihydropyrimidine dehydrogenase by 5-propynyluracil, a metabolite of the anti-varicella zoster virus agent netivudine
-
Peck R, Wiggs R, Callaghan J, Wootton R, Crome P, Fraser I, et al. Inhibition of dihydropyrimidine dehydrogenase by 5-propynyluracil, a metabolite of the anti-varicella zoster virus agent netivudine. Clin Pharmacol Ther 1996;59:22-31.
-
(1996)
Clin Pharmacol Ther
, vol.59
, pp. 22-31
-
-
Peck, R.1
Wiggs, R.2
Callaghan, J.3
Wootton, R.4
Crome, P.5
Fraser, I.6
-
25
-
-
0027135995
-
5-Ethynyluracil (776C85): Inactivation of dihydropyrimidine dehydrogenase in vivo
-
Spector T, Harrington JA, Porter DJT. 5-Ethynyluracil (776C85): Inactivation of dihydropyrimidine dehydrogenase in vivo. Biochem Pharmacol 1993;12:2243-8.
-
(1993)
Biochem Pharmacol
, vol.12
, pp. 2243-2248
-
-
Spector, T.1
Harrington, J.A.2
Porter, D.J.T.3
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