SOK2 may regulate cyclic AMP-dependent protein kinase-stimulated growth and pseudohyphal development by repressing transcription

Molecular and Cellular Biology

Volumn 15, Issue 12, 1995, Pages 6854-6863

  Ward, Mary P ^a   Gimeno, Carlos J ^b,c   Fink, Gerald R ^b   Garrett, Stephen ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE;

ARTICLE; ASPERGILLUS NIDULANS; CELL DIFFERENTIATION; ENZYME REGULATION; FUNGUS GROWTH; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; YEAST;

ASPERGILLUS; EMERICELLA NIDULANS; FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 0028790841     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.15.12.6854     Document Type: Article

References (69)

1. Baroni, M. D., P. Monti, and L. Alberghina. 1994. Repression of growthregulated G1 cyclin expression by cyclic AMP in budding yeast. Nature (London) 371:339-342.
2. Broach, J. R. 1991. RAS genes in Saccharomyces cerevisiae: signal transduction in search of a pathway. Trends Genet. 7:28-33.
3. Broach, J. R., and R. J. Besehenes. 1990. The function of RAS genes in Saccharomyces cerevisiae. Adv. Cancer Res. 54:79-138.
4. Cameron, S., L. Levin, M. Zoller, and M. Wigler. 1988. cAMP-independent control of sporulation, glycogen metabolism, and heat shock resistance in S. cerevisiae. Cell 53:555-566.
5. Cannon, J., and K. Tatchell. 1987. Characterization of Saccharomyces cerevisiae genes encoding subunits of cAMP-dependent protein kinase. Mol. Cell. Biol. 7:2653-2663.
6. Casadaban, M. J., A. Martinez-Arias, S. K. Shapiro, and J. Chou. 1983. β-Galactosidase gene fusions for analyzing gene expression in Eschierichia call and yeast. Methods Enzymol. 100:293-308.
7. Cherry, J. R., T. R. Johnson, C. Dollard, J. R. Shuster, and C. L. Denis. 1989. Cyclic AMP-dependent protein kinase phosphorylates and inactivates the yeast transcriptional activator ADR1. Cell 56:409-419.
8. c mutations enhance the ability of ADR1 to activate transcription by a mechanism that is independent of effects on cyclic AMP-dependent protein kinase phosphorylation of Ser-130. Mol. Cell. Biol. 12:1507-1514.
9. Denis, C. L., B. E. Kemp, and M. J. Zoller. 1991. Substrate specificities for yeast and mammalian cAMP-dependent protein kinase are similar but not identical. J. Biol. Chem. 266:17932-17935.
10. Deschenes, R. J. and J. R. Broach. 1987. Fatty acylation is important but not essential for Sacchuromyces cerevisiae RAS function. Mol. Cell. Biol. 7:2344-2351.
11. Dohrmann, P. R., G. Butler, K. Tamai, S. Dorland, J. R. Greene, D. J. Thiele, and D. J. Stillman. 1992. Parallel pathways of gene regulation: homologous regulators SWI5 and ACE2 differentially control transcription of HO and chitinase. Genes Dev. 6:93-104.
12. Engleberg, D., C. Klein, H. Martinetto, K. Struhl, and M. Karin. 1994. The UV response involving the Ras signalling pathway and AP-1 transcription factors is conserved between yeast and mammals. Cell 77:381-390.
13. Engleberg, D., E. Zandi, C. S. Parker, and M. Karin. 1994. The yeast and mammalian Ras pathways control transcription of heat shock genes independently of heat shock transcription factors. Mol. Cell. Biol. 14:4929-4937.
14. Fedor-Chaiken, M., R. J. Deschenes, and J. R. Broach. 1990. SRV2, a gene required for RAS activation of adenylate cyclase in yeast. Cell 61:329-340.
15. 1. Genes Dev. 6:2417-2428.
16. Francois, J. M., S. Thompson-Jaeger, J. Skroch, U. Zellenka, W. Spevak, and K. Tatchell. 1992. GAC1 may encode a regulatory subunit for protein phosphatase type 1 in S. cerevisiae. EMBO J. 11:87-96.
17. Garrett, S., and J. Broach. 1989. Loss of Ras activity in Saccharomyces cerevisiae is suppressed by disruptions of a new kinase gene, YAK1, whose product may act downstream of the cAMP-dependent protein kinase. Genes Dev. 3:1336-1348.
18. Garrett, S., M. M. Menold, and J. R. Broach. 1991. The Saccharomyces cerevisiae YAK1 gene encodes a protein kinase that is induced by arrest early in the cell cycle. Mol. Cell. Biol. 11:4045-4052.
19. Gietz, R. D., and A. Sugino. 1988. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six base pair restriction sites. Gene 74:527-534.
20. Gimeno, C. J., and G. R. Fink. 1994. Induction of pseudohyphal growth by overexpression of PHD1, a Saccharomyces cerevisiae gene related to transcriptional regulators of fungal development. Mol. Cell. Biol. 14:2100-2112.
21. Gimeno, C. J., P. O. Ljungdahl, C. A. Styles, and G. R. Fink. 1992. Unipolar cell divisions in the yeast S. cerevisiae lead to filamentous growth: regulation by starvation and RAS. Cell 68:1077-1090.
22. Gold, S., G. Duncan, K. Barrett, and J. Kronstad. 1994. cAMP regulates morphogenesis in the fungal pathogen Ustilago maydis. Genes Dev. 8:2805-2816.
23. Grenson, M., M. Mousset, M. J. M. Wiame, and J. Bechet. 1966. Multiplicity of the amino acid permeases in S. cerevisiae. 1. Evidence for a specific arginine transporting system. Biochim. Biophys. Acta 127:325-338.
24. Guarente, L. 1993. Synthetic enhancement in gene interaction: a genetic tool come of age. Trends Genet. 9:362-366.
25. Hartley, A. D., M. P. Ward, and S. Garrett. 1993. The Yak1 protein kinase of Saccharomyces cerevisiae moderates thermotolerance and inhibits growth by an Sch9 protein kinase-independent mechanism. Genetics 136:465-474.
26. Hubler, L., J. Bradshaw-Rouse, and W. Heideman. 1993. Connections between the Ras-cyclic AMP pathway and G1 cyclin expression in the budding yeast Saccharomyces cerevisiae. Mol. Cell. Biol. 13:6274-6282.
27. Ito, H., Y. Fukuda, K. Murata, and A. Kimura. 1983. Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153:163-168.
28. Johnston, G. C., J. R. Pringle, and L. H. Hartwell. 1977. Coordination of growth with cell division in the yeast Saccharomyces cerevisiae. Exp. Cell Res. 105:79-98.
29. Kataoka, T., S. Powers, C. McGill, O. Fasano, J. Strathern, J. Broach, and M. Wigler. 1984. Genetic analysis of yeast RASI and RAS2 genes. Cell 37:437-445.
30. Kemp, B. E., and R. B. Pearson. 1990. Protein kinase recognition sequence motifs. Trends Biochem. Sci. 15:342-346.
31. Klein, C., and K. Struhl. 1994. Protein kinase A mediates growth-regulated expression of yeast ribosomal protein genes by modulating RAP1 transcriptional activity. Mol. Cell. Biol. 14:1920-1928.
32. 1 to S phase. Science 261:1551-1557.
33. Kohrer, K., and H. Domdey. 1991. Preparation of high molecular weight RNA. Methods Enzymol. 194:398-401.
34. Lalli, E., and P. Sassone-Corsi. 1994. Signal transduction and gene regulation: the nuclear response to cAMP. J. Biol. Chem. 269:17359-17362.
35. Lane, M. E., and D. Kalderon. 1993. Genetic investigation of cAMP-dependent protein kinase function in Drosophila development. Genes Dev. 7:1229-1243.
36. Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
37. Marchler, G., C. Schuller, G. Adam, and H. Ruis. 1993. A Saccharomyces cerevisiae UAS element controlled by protein kinase A activates transcription in response to a variety of stress conditions. EMBO J. 12:1997-2003.
38. Matsumoto, K., I. Uno, Y. Oshima, and T. Ishikawa. 1982. Isolation and characterization of yeast mutants deficient in adenylate cyclase and cAMP-dependent protein kinase. Proc. Natl. Acad. Sci. USA 79:2355-2359.
39. Mazzoni, C., P. Zarzov, A. Rambourg, and C. Mann. 1993. The SLT2 (MPK1) MAP kinase homolog is involved in polarized cell growth in Saccharomyces cerevisiae. J. Cell. Biol. 123:1821-1833.
40. Michaeli, T., J. Field, R. Ballester, K. O'Neill, and M. Wigler. 1989. Mutants of H-ras that interfere with RAS effector function in Saccharomyces cerevisiae. EMBO J. 8:3039-3044.
41. Miller, K. Y., T. M. Toennis, T. H. Adams, and B. L. Miller. 1991. Isolation and transcriptional characterization of a morphological modifier: the Aspergillus nidulans stunted (stuA) gene. Mol. Gen. Genet. 227:285-292.
42. Miller, K. Y., J. Wu, and B. L. Miller. 1992. StuA is required for cell pattern formation in Aspergillns. Genes Dev. 6:1770-1782.
43. Mochizuki, N., and M. Yamamoto. 1992. Reduction in the intraceltular cAMP level triggers initiation of sexual development in fission yeast. Mol. Gen. Genet. 233:17-24.
44. Nasmyth, K., and L. Dirick. 1991. The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast. Cell 66:995-1013.
45. Neuman-Silberberg, F. S., S. Bhattacharya, and J. R. Broach. 1995. Nutrient availability and the RAS/cyclic AMP pathway both induce expression of ribosomal protein genes in Saccharomyces cerevisiae but by different mechanisms. Mol. Cell. Biol. 15:3187-3196.
46. Nikawa, J., S. Cameron, T. Toda, K. M. Ferguson, and M. Wigler. 1987. Rigorous feedback control of cAMP levels in Saccharomyces cerevisiae. Genes Dev. 1:931-937.
47. Nogi, Y., and T. Fukasawa. 1989. Functional domains of a negative regulatory protein. Ga180, of Saccharomyces cerevisiae. Mol. Cell. Biol. 9:3009-3017.
48. Ogas, J., B. J. Andrews, and I. Herskowitz. 1991. Transcriptional regulation of CLN1. CLN2. and a putative new G1 cyclin (HCS26) by SWI4, a positive regulator of G1-specific transcription. Cell 66:1015-1026.
49. Perkins, D. D. 1949. Biochemical mutants of the smut fungus Ustilago maydis. Genetics 34:607-629.
50. Primig, M., S. Sockanathan, H. Auer, and K. Nasmyth. 1992. Anatomy of a transcription factor important for the start of the cell cycle in Saccharomyces cerevisiae. Nature (London) 358:593-597.
51. Riles, L., J. E. Dutchick, A. Baktha, B. K. McCauley, E. C. Thayer, M. P. Leckie, V. V. Braden, J. E. Depke, and M. V. Olson. 1993. Physical maps of the 6 smallest chromosomes of Saccharomyces cerevisiae at a resolution of 2.6-kilobase pairs. Genetics 34:81-150.
52. Robinson, L. C., M. M. Menold, S. Garrett, and M. R. Culbertson. 1993. Casein kinase I-like protein kinases encoded by YCK1 and YCK2 are required for yeast morphogenesis. Mol. Cell. Biol. 13:2870-2881.
53. Rose, M. D., P. Novick, J. H. Thomas, D. Botstein, and G. R. Fink. 1987. A Saccharomyces cerevisiae genomic plasmid bank based on a centromerecontaining shuttle vector. Gene 60:237-243.
54. Rose, M. D., F. Winston, and P. Hieter. 1989. Methods in yeast genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
55. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
56. Sass, P., J. Field, J. Nikawa, T. Toda, and M. Wigler. 1986. Cloning and characterization of the high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 83:9303-9307.
57. Shepherd, M. G. 1988. Morphogenetic transformation of fungi. Curr. Top. Med. Mycol. 2:278-304.
58. Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
59. Simon, M.-N., O. Pelegrini, M. Vernon, and R. R. Kay. 1992. Mutation of protein kinase A causes heterochronic development of Diciyosteliutn. Nature (London) 356:171-172.
60. Sussel, L., and D. Shore. 1991. Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: isolation of viable mutants affecting both silencing and telomere length. Proc. Natl. Acad. Sci. USA 88:7749-7753.
61. Tanaka, K., K. Matsumoto, and A. Toh-e. 1988. Dual regulation of the expression of the polyubiquitin gene by cyclic AMP and heat shock in yeast. EMBO J. 7:495-502.
62. Thevelein, J. M. 1992. The RAS-adenylate cyclase pathway and cell cycle control in Saccharomyces cerevisiae. Antonie Leeuwenhoek 62:109-130.
63. Toda, T., S. Cameron, P. Sass, M. Zoller, and M. Wigler. 1987. Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50:277-287.
64. Toda, T., I. Uno, T. Ishikawa, S. Powers, T. Kataoka, D. Broek, S. Cameron, J. Broach, K. Matsumoto, and M. Wigler. 1985. In yeast, RAS proteins are controlling elements of adenylate cyclase. Cell 40:27-36.
65. Tokiwa, G., M. Tyers, T. Volpe, and B. Futcher. 1994. Inhibition of G1 cyclin activity by the Ras/cAMP pathway in yeast. Nature (London) 371:342-345.
66. Van Zyl, W., W. Huang, A. A. Sneddon, M. Stark, S. Camier, M. Werner, C. Marck, A. Sentenac, and J. R. Broach. 1992. Inactivation of the protein phosphatase 2A regulatory subunit A results in morphological and transcriptional defects in Saccharomyces cerevisiae. Mol. Cell. Biol. 12:4946-4959.
67. Ward, M. P. Unpublished data.
68. Ward, M. P., and S. Garrett. 1994. Suppression of a yeast cyclic AMP-dependent protein kinase defect by overexpression of SOK1, a yeast gene exhibiting sequence similarity to a developmentally regulated mouse gene. Mol. Cell. Biol. 14:5619-5627.
69. Woodcock, D. M., P. J. Crowther, J. Doherty, S. Jefferson, E. DeCruz, M. Noyer-Weidner, S. S. Smith, M. Z. Michael, and M. W. Graham. 1989. Quantitative evaluation of Escherichia coli host strains for tolerance to cytosine methylation in plasmid and phage recombinants. Nucleic Acids Res. 17:3469-3478.