Evidence for thiol-dependent production of oxygen radicals by 4-methyl- 5-pyrazinyl-3H-1,2-dithiole-3-thione (oltipraz) and 3H-1,2-dithiole-3- thione: Possible relevance to the anticarcinogenic properties of 1,2- dithiole-3-thiones

Chemical Research in Toxicology

Volumn 10, Issue 3, 1997, Pages 296-301

  Kim, Woongki ^a   Gates, Kent S ^a,b  

^a UNIVERSITY OF MISSOURI   (United States)

^b University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DITHIOLE 3 THIONE DERIVATIVE; 3H 1,2 DITHIOLE 3 THIONE; ANTINEOPLASTIC AGENT; DIMETHYL SULFOXIDE; OLTIPRAZ; OXYGEN RADICAL; SCAVENGER; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER PREVENTION; CHEMOPROPHYLAXIS; DNA CLEAVAGE; ENZYME INDUCTION; REACTION ANALYSIS;

ANAEROBIOSIS; ANTICARCINOGENIC AGENTS; BUFFERS; CHELATING AGENTS; CHEMISTRY, PHYSICAL; DNA DAMAGE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FREE RADICAL SCAVENGERS; FREE RADICALS; PLASMIDS; PYRAZINES; SULFHYDRYL COMPOUNDS; THIONES; THIOPHENES;

EID: 0030944162     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx9601667     Document Type: Article

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