The propeptide of the vitamin K-dependent carboxylase substrate accelerates formation of the γ-glutamyl carbanion intermediate

Biochemistry

Volumn 36, Issue 21, 1997, Pages 6384-6390

  Li, Shuying ^a   Furie, Barbara C ^b   Furie, Bruce ^b   Walsh, Christopher T ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b TUFTS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VITAMIN K DEPENDENT CARBOXYLASE;

ARTICLE; CHO CELL; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME SUBSTRATE; PEPTIDE ANALYSIS; PRIORITY JOURNAL; RADIOASSAY;

1-CARBOXYGLUTAMIC ACID; CALIBRATION; CARBON DIOXIDE; CARBON RADIOISOTOPES; CARBON-CARBON LIGASES; CATALYSIS; KINETICS; LIGASES; PROTEIN PRECURSORS; SODIUM BICARBONATE; SUBSTRATE SPECIFICITY; TRITIUM; VITAMIN K;

EID: 0030943891     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi962816b     Document Type: Article

References (25)

1. Cheung, Y., & Walsh, C. (1976) Biochemistry 15, 3749-3754.
2. Dowd, P., Ham, S. W., & Geib, S. J. (1991) J. Am. Chem. Soc. 113, 7734-7743.
3. Dowd, P., Ham, S., & Hershline, R. (1992) J. Am. Chem. Soc. 114, 7613-7617.
4. Dowd, P., Hershline, R., Ham, S. W., & Naganathan, S. (1995) Science 269, 1684-1691.
5. Ducroq, C., Righini-Tapie, A., Azerad, R., Green, J. F., Friedman, P. A., Beaucourt, J., & Rousseau, B. (1986) J. Chem. Soc., Perkin Trans. I, 1323-1328.
6. Friedman, P. A., Shia, M. A., Gallop, P. M., & Griep, A. E. (1979) Proc. Natl. Acad. Sci. U.S.A. 76, 3126-3129.
7. Hauschka, P. V. (1979) Biochemistry 18, 4992-4999.
8. Hubbard, B. R., Jacobs, M., Ulrich, M., Walsh, C. T., Furie, B., & Furie, B. C. (1989) J. Biol. Chem. 264, 14145-14150.
9. Jorgensen, M. J., Cantor, A. B., Furie, B. C., Brown, C. L., Shoemaker, C. B., & Furie, B. (1987) Cell 48, 185-191.
10. Knobloch, J. E., & Suttie, J. W. (1987) J. Biol. Chem. 262, 15334-15337.
11. Kuliopulos, A., Cieurzo, C. E., Furie, B., Furie, B. C., & Walsh, C. T. (1992a) Biochemistry 31, 9436-9444.
12. Kuliopulos, A., Hubbard, B., Lam, Z., Koski, I., Furie, B., Furie, B. C., & Walsh, C. T. (1992b) Biochemistry 31, 7722-7728.
13. Larson, A. E., Friedman, P. A., & Suttie, J. W. (1981) J. Biol. Chem. 256, 11032-11035.
14. Mann, K. G., Jenny, R. J., & Krishnaswamy, S. (1988) Annu. Rev. Biochem. 57, 915-956.
15. Maréchal, P. D.-L., Ducrocq, C., Marquet, A., & Azerad, R. (1984) J. Biol. Chem. 259, 15010-15012.
16. Rehemtulla, A., Roth, D. A., Wasley, L. C., Kuliopulos, A., Walsh, C. T., Furie, B., Furie, B. C., & Kaufman, R. J. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 4611-4615.
17. Roth, D. A., Rehemtulla, A., Kaufman, R. J., Walsh, C. T., Furie, B., & Furie, B. C. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 8372-8376.
18. Roth, D. A., Whirl, M. L., Velazquez-Estades, L. J., Walsk, C. T., Furie, B., & Furie, B. C. (1995) J. Biol. Chem. 270, 5305-5311.
19. Sugiura, I., Furie, B., Walsh, C. T., & Furie, B. C. (1996) J. Biol. Chem. 271, 17837-17844.
20. Thampy, K. G., Huang, W., & Wakil, S. J. (1988) Arch. Biochem. Biophys. 183, 113-122.
21. Ulrich, M., Furie, B., Jacob, M., Vermeer, C., & Furie, B. C. (1988) J. Biol. Chem. 263, 9697-9702.
22. Varnum, B. C., Young, C., Elliott, G., Garcia, A., Bartlay, T. D., Fridell, Y.-W., Hunt, R. W., et al. (1995) Nature 373, 623-626.
23. Walsh, C. (1979) in Enzymatic Reaction Mechanisms (Bartlett, A. C., Ed.) p 114, W. H. Freeman and Company, New York.
24. Wu, S.-M., Cheung, W.-F., Frazier, D., & Staford, D. W. (1991) Science 254, 1634-1636.
25. Yamada, M., Kuliopulos, A., Nelson, N. P., Roth, D. A., Furie, B., Furie, B. C., & Walsh, C. T. (1995) Biochemistry 34, 481-489.