Profactor IX propeptide and glutamate substrate binding sites on the vitamin K-dependent carboxylase identified by site-directed mutagenesis

Journal of Biological Chemistry

Volumn 271, Issue 30, 1996, Pages 17837-17844

  Sugiura, Isamu ^a   Furie, Bruce ^a,b   Walsh, Christopher T ^c   Furie, Barbara C ^a,b  

^a TUFTS MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 9; PROTEIN PRECURSOR; VITAMIN K DEPENDENT CARBOXYLASE;

ANIMAL CELL; ARTICLE; BINDING SITE; CHO CELL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME SUBSTRATE; EXPRESSION VECTOR; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CARBON-CARBON LIGASES; CATTLE; CHO CELLS; CRICETINAE; FACTOR IX; GLUTAMIC ACID; KINETICS; LIGASES; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN PRECURSORS; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; VITAMIN K 1;

EID: 0029954236     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.30.17837     Document Type: Article

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