Nonadrenergic contractile response of guinea pig portal vein to electrical field stimulation mimics response to UTP but not to ATP

Journal of Cardiovascular Pharmacology

Volumn 29, Issue 3, 1997, Pages 360-366

  Ishizaki, Michiyo ^a   Iizuka, Yasutaka ^a   Suzuki Kusaba, Mizue ^a   Kimura, Tomohiko ^b   Satoh, Susumu ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b NIPPON DENTAL UNIVERSITY   (Japan)

Author keywords

, methylene ATP; ATP; DIDS; Nonadrenergic contraction; Portal vein; Reactive blue 2; Suramin; Sympathetic nerve stimulation; UTP

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; ADENOSINE TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; CHLORPHENIRAMINE MALEATE; CIBACRON BLUE F3GA; CIMETIDINE; GUANETHIDINE; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR; PHENTOLAMINE; PROPRANOLOL; PURINE P2 RECEPTOR; PURINE P2X RECEPTOR; PURINE P2Y RECEPTOR; RESERPINE; SURAMIN; TETRODOTOXIN; THEOPHYLLINE; URIDINE TRIPHOSPHATE;

ALPHA ADRENERGIC RECEPTOR BLOCKING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ELECTROSTIMULATION; GUINEA PIG; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; NORADRENALIN RELEASE; PORTAL VEIN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; SYMPATHETIC NERVE; VENOCONSTRICTION;

4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; ADENOSINE TRIPHOSPHATE; ADRENERGIC ALPHA-ANTAGONISTS; ADRENERGIC UPTAKE INHIBITORS; ANIMALS; ELECTRIC STIMULATION; GUANETHIDINE; GUINEA PIGS; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; NG-NITROARGININE METHYL ESTER; PHENTOLAMINE; PORTAL VEIN; RESERPINE; SURAMIN; TETRODOTOXIN; TRIAZINES; URIDINE TRIPHOSPHATE;

EID: 0030935122     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199703000-00009     Document Type: Article

References (38)

1. Burnstock G. The changing face of autonomic neurotramsmission. Acta Physiol Scand 1986;126:67-91.
2. Burnstock G, Kennedy C. A dual function of adenosine 5́-triphosphate in the regulation of vascular tone: excitatory cotransmitter with noradrenaline from perivascular nerves and locally released inhibitory intravascular agent. Circ Res 1986;58:319-30.
3. Burnstock G. Co-transmission. Arch Int Pharmacodyn 1990; 304:7-33.
4. von Kügelgen I, Starke K. Noradrenaline-ATP co-transmission in the sympathetic nervous system. Trends Pharmacol Sci 1991;12:319-24.
5. von Kügelgen I, Starke K. Noradrenaline and adenosine triphosphate as co-transmitters of neurogenic vasoconstriction in rabbit mesenteric artery. J Physiol (Lond) 1985;367:435-55.
6. Burnstock G, Warland JJI. A pharmacological study of the rabbit saphenous artery in vitro: a vessel with a large purinergic contractile response to sympathetic nerve stimulation. Br J Pharmacol 1987;90:111-20.
7. Muramatsu I. The effect of reserpine on sympathetic, purinergic neurotransmission in the isolated mesenteric artery of the dog: a pharmacological study. Br J Pharmocol 1987;91:467-74.
8. Machaly M, Dalziel HH, Sneddon P. Evidence for ATP as a Cotransmitter in dog mesenteric artery. Eur J Pharmacol 1988; 147:83-91.
9. Brizzolara AL, Burnstock G. Evidence for noradrenergic-purinergic cotransmission in the hepatic artery of the rabbit. Br J Pharmocol 1990;99:835-9.
10. Evans RJ, Cunname TC. Relative contributions of ATP and noradrenaline to the nerve evoked contaction of rabbit jejunal artery. Naunyn-Schmiedebergs Arch Pharmacol 1992;345:424-30.
11. 2-purinoceptor antagonist in the mouse vas deferens. Br J Pharmacol 1988;93:243-5.
12. 2-purinoceptor subtypes - an update. Arch Int Pharmacodyn 1990;303:30-50.
13. 2-purinoceptor agonists and purinergic nerve stimulation in the guinea pig urinary bladder and Taenia coli. Br J Pharmacol 1990;99:617-21.
14. Mallard N, Marshall R, Sithers A, Spriggs B. Suramin: a selective inhibitor of purinergic neurotransmission in the rat isolated vas deferens. Eur J Pharmacol 1992;220:1-10.
15. 2X-purinoceptor. Br J Pharmacol 1987;90:383-91.
16. 2X-purinoceptors in rat vas deferens. Br J Pharmacol 1994;112:690-4.
17. 2-purinoceptor, in rabbit ear artery. Naunyn-Schmiedebergs Arch Pharmacol 1987;336:556-60.
18. Seifert R, Schultz G. Involvement of pyrimidinoceptors in the regulation of cell functions by uridine and by uracil nucleotides. Trends Pharmacol Sci 1989;10:365-9.
19. 2X-receptor, in rabbit basilar artery: a receptor for pyrimidine nucleotides and a receptor for purine nucleotides. Naunyn-Schmiedebergs Arch Pharmacol 1990;341:538-46.
20. 2X-purinoceptors. Blood Vessels 1990;27:352-64.
21. Liu SF, Crawley DE, Evans TW, Barnes PJ. Endogenous nitric oxide modulates adrenergic neural vasoconstriction in guinea pig pulmonary artery. Br J Pharmacol 1991;104:565-9.
22. Buga GM, Ignarro LJ. Electrical field stimulation causes endothelium-dependent and nitric oxide-mediated relaxation of pulmonary artery. Am J Physiol 1992;262:H973-9.
23. Brizzolara AL, Crowe R, Burnstock G. Evidence for the involvement of both ATP and nitric oxide in non-adrenergic, non-cholinergic inhibitory neurotransmission in the rabbit portal vein. Br J Pharmacol 1993;109:606-8.
24. Warland JJI, Burnstock G. Effects of reserpine and 6-hydroxydopamine on the adrenergic and purinergic components of sympathetic nerve responses of the rabbit saphenous artery. Br J Pharmacol 1987;92:871-80.
25. Evans RJ, Surprenant A. Vasoconstriction of guinea pig submucosal arterioles following sympathetic nerve stimulation is mediated by the release of ATP. Br J Pharmacol 1992;106: 242-9.
26. 2-purinoceptors mediate both vasodilation (via the endothelium) and vasoconstriction of the isolated rat femoral artery. Eur J Pharmacol 1985;107:161-8.
27. 2-purinergic receptor subtypes on endothelium and smooth muscle in canine blood vessels. J Pharmacol Exp Ther 1987;241:501-6.
28. 2-purinoceptor subtypes in the isolated perfused mesenteric bed of the rat. Br J Pharmacol 1988;95:637-45.
29. 2Y-purinoceptors in the rabbit hepatic arterial vasculature. Br J Pharmacol 1991;103:1108-13.
30. Mathie RT, Ralevic V, Alexander B, Burnstock G. Nitric oxide is the mediator of ATP-induced dilatation of the rabbit hepatic arterial vascular bed. Br J Pharmacol 1991;103:1602-6.
31. 2-purinoceptor antagonists on degradation of adenine nucleotides by ecto-nucleotidases in folliculated oocytes of Xenopus laevis. Biochem Pharmacol 1996;51:897-901.
32. 2-purinoceptors in guinea pig Taenia colt. Naunyn-Schmiedebergs Arch Pharmacol 1996;353:445-51.
33. Trinkle ML, Siegman MJ, Butler TM. Metabolic characteristics of alpha-toxin-permeabilized snooth muscle. Am J Physiol 1994; 266:C1673-83.
34. Meghji P, Burnstock G. Inhibition of extracellular ATP degradation in endothelial cells. Life Sci 1995;57:763-71.
35. Beulers MW, Kerkhof CJ, van Rhee MA, et al. Suramin analogs, divalent cations and ATPγS as inhibitors of exto-ATPase. Naunyn-Schmiedebergs Arch Pharmacol 1995;351:523-8.
36. 2X-purinoceptor ligands. Br J Pharmacol 1994;113:1432-8.
37. 2Y purinoceptors? Pharmacol Ther 1994;64:445-75.
38. 2 purinoceptors. Drug Dev Res 1996;38:67-71.