메뉴 건너뛰기




Volumn 24, Issue 3, 1997, Pages 233-241

Dehydroepiandrosterone (DHEA) and aging

Author keywords

Aging; Dehydroepiandrosterone; Dehydroepiandrosterone sulfate

Indexed keywords

LIPID; PRASTERONE; STEROID; SULFATASE;

EID: 0030933507     PISSN: 01674943     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4943(96)00761-3     Document Type: Review
Times cited : (42)

References (47)
  • 1
    • 0028985525 scopus 로고
    • Dehydroepiandrosterone functions more than an antiglucocorticoid in preserving immunocompetence after thermal injury
    • Araneo, B. and Daynes, R. (1995): Dehydroepiandrosterone functions more than an antiglucocorticoid in preserving immunocompetence after thermal injury. Endocrinology, 136, 393-401.
    • (1995) Endocrinology , vol.136 , pp. 393-401
    • Araneo, B.1    Daynes, R.2
  • 2
    • 0027412229 scopus 로고
    • Reversal of the immunosenescent phenotype by dehydroepiandrosterone: Hormone treatment provides an adjuvant effect on the immunization of aged mice with recombinant hepatitis B antigen
    • Araneo, B.A., Woods, M.L. and Daynes, R.A. (1993): Reversal of the immunosenescent phenotype by dehydroepiandrosterone: hormone treatment provides an adjuvant effect on the immunization of aged mice with recombinant hepatitis B antigen. J. Infect. Dis., 167, 830-840.
    • (1993) J. Infect. Dis. , vol.167 , pp. 830-840
    • Araneo, B.A.1    Woods, M.L.2    Daynes, R.A.3
  • 3
    • 0028280489 scopus 로고
    • A prospective study of dehydroepiandrosterone sulfate and cognitive function in an older population: The Rancho Bernardo study
    • Barrett-Connor, E. and Edelstein, S.L. (1994): A prospective study of dehydroepiandrosterone sulfate and cognitive function in an older population: the Rancho Bernardo study. J. Am. Geriatr. Soc., 42, 420-423.
    • (1994) J. Am. Geriatr. Soc. , vol.42 , pp. 420-423
    • Barrett-Connor, E.1    Edelstein, S.L.2
  • 4
    • 0028944061 scopus 로고
    • Dehydroepiandrosterone sulfate does not predict cardiovascular death in postmenopausal women
    • The Rancho Bernardo study
    • Barrett-Connor, E. and Goodman-Gruen, D. (1995): Dehydroepiandrosterone sulfate does not predict cardiovascular death in postmenopausal women. The Rancho Bernardo study. Circulation, 91, 1757-1760.
    • (1995) Circulation , vol.91 , pp. 1757-1760
    • Barrett-Connor, E.1    Goodman-Gruen, D.2
  • 5
    • 0022921501 scopus 로고
    • A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease
    • Barrett-Connor, E., Khaw, K.T. and Yen, S. (1986): A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease. N. Engl. J. Med., 315, 1519-1524.
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1519-1524
    • Barrett-Connor, E.1    Khaw, K.T.2    Yen, S.3
  • 6
    • 0025134321 scopus 로고
    • Dehydroepiandrosterone sulfate and breast cancer risk
    • Barrett-Connor, E., Friedlander, N.J. and Khaw, K.T. (1990): Dehydroepiandrosterone sulfate and breast cancer risk. Cancer Res., 50, 6571-6574.
    • (1990) Cancer Res. , vol.50 , pp. 6571-6574
    • Barrett-Connor, E.1    Friedlander, N.J.2    Khaw, K.T.3
  • 7
    • 0027458842 scopus 로고
    • A prospective study of dehydroepiandrosterone sulfate (DHEAS) and bone mineral density in older men and women
    • Barrett-Connor, E., Silverstein, D.K. and Edelstein, S.L. (1993): A prospective study of dehydroepiandrosterone sulfate (DHEAS) and bone mineral density in older men and women. Am. J. Epidemiol., 137, 201-206.
    • (1993) Am. J. Epidemiol. , vol.137 , pp. 201-206
    • Barrett-Connor, E.1    Silverstein, D.K.2    Edelstein, S.L.3
  • 8
    • 0028949171 scopus 로고
    • Studies on dehydroepiandrosterone (DHEA) and its sulphate during aging
    • Baulieu, E.E. (1995): Studies on dehydroepiandrosterone (DHEA) and its sulphate during aging, C. R. Acad. Sci. Paris., 318, 7-11.
    • (1995) C. R. Acad. Sci. Paris. , vol.318 , pp. 7-11
    • Baulieu, E.E.1
  • 10
    • 0028029751 scopus 로고
    • Disparate effects of insulin reduction with diltiazem on serum dehydroepiandrosterone sulfate levels in obese hypertensive men and women
    • Beer, N.A., Jakubowicz, D.J., Beer, R.M. and Nestler, J.E. (1994): Disparate effects of insulin reduction with diltiazem on serum dehydroepiandrosterone sulfate levels in obese hypertensive men and women. J. Clin. Endocrinol. Metab., 79, 1077-1081.
    • (1994) J. Clin. Endocrinol. Metab. , vol.79 , pp. 1077-1081
    • Beer, N.A.1    Jakubowicz, D.J.2    Beer, R.M.3    Nestler, J.E.4
  • 12
    • 0028206425 scopus 로고
    • Dehydroepiandrosterone sulphate (DHEAS) in the oldest old, aged 85 and over
    • Birkenhäger-Gillesse, E.G., Derksen, J. and Lagaay, A.M. (1994): Dehydroepiandrosterone sulphate (DHEAS) in the oldest old, aged 85 and over. Ann N.Y. Acad, Sci., 719, 543-552.
    • (1994) Ann N.Y. Acad, Sci. , vol.719 , pp. 543-552
    • Birkenhäger-Gillesse, E.G.1    Derksen, J.2    Lagaay, A.M.3
  • 13
    • 0028940840 scopus 로고
    • Replacement of dehydroepiandrosterone enhances T-lymphocyte insulin binding in postmenopausal women
    • Casson, P.R., Faquin, L.C. and Stentz, F.B. (1995): Replacement of dehydroepiandrosterone enhances T-lymphocyte insulin binding in postmenopausal women. Fertil. Steril., 63, 1027-1031.
    • (1995) Fertil. Steril. , vol.63 , pp. 1027-1031
    • Casson, P.R.1    Faquin, L.C.2    Stentz, F.B.3
  • 14
    • 0021334185 scopus 로고
    • Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes-obesity mutants and in aged normal mice
    • Coleman, D.L., Schwizer, R.W. and Leiter, E.H. (1983): Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes-obesity mutants and in aged normal mice. Diabetes, 33, 26-32.
    • (1983) Diabetes , vol.33 , pp. 26-32
    • Coleman, D.L.1    Schwizer, R.W.2    Leiter, E.H.3
  • 15
    • 0025941858 scopus 로고
    • Receptor binding and electrophysiological effects of dehydroepiandrosterone sulfate, an antagonist of the GABA receptor
    • Demirgören, S., Majewska, M.D., Spivak, C.E. and London, E.D. (1991): Receptor binding and electrophysiological effects of dehydroepiandrosterone sulfate, an antagonist of the GABA receptor. Neuroscience, 45, 127-135.
    • (1991) Neuroscience , vol.45 , pp. 127-135
    • Demirgören, S.1    Majewska, M.D.2    Spivak, C.E.3    London, E.D.4
  • 17
    • 0027388918 scopus 로고
    • Inhibition of accelerated coronary atherosclerosis with dehydroepiandrosterone in the heterotopic rabbit model of cardiac transplantation
    • Eich, D.M., Nestler, J.E., Johnson, D.E., Dworkin, G.H., Daijin, K., Wechsler, A.S. and Hess, M.L. (1993): Inhibition of accelerated coronary atherosclerosis with dehydroepiandrosterone in the heterotopic rabbit model of cardiac transplantation. Circulation, 87, 261-269.
    • (1993) Circulation , vol.87 , pp. 261-269
    • Eich, D.M.1    Nestler, J.E.2    Johnson, D.E.3    Dworkin, G.H.4    Daijin, K.5    Wechsler, A.S.6    Hess, M.L.7
  • 18
    • 0023747367 scopus 로고
    • Reduction of atherosclerosis by administration of dehydroepiandrosterone
    • A study in the hypercholesterolemic New Zealand white rabbit with aortic intimai injury
    • Gordon, G.B., Bush, D.E. and Weisman, H.F. (1988): Reduction of atherosclerosis by administration of dehydroepiandrosterone. A study in the hypercholesterolemic New Zealand white rabbit with aortic intimai injury. J. Clin. Invest., 82, 712-720.
    • (1988) J. Clin. Invest. , vol.82 , pp. 712-720
    • Gordon, G.B.1    Bush, D.E.2    Weisman, H.F.3
  • 19
    • 0025944397 scopus 로고
    • Suppression of circulating Δ4 androstenedione and dehydroepiandrosterone sulfate during oral glucose tolerance test in normal females
    • Hubert, G.D., Schriock, E.D., Givens, J.R. and Buster, J.E. (1991): Suppression of circulating Δ4 androstenedione and dehydroepiandrosterone sulfate during oral glucose tolerance test in normal females. J. Clin. Endocrinol. Metab., 73, 781-784.
    • (1991) J. Clin. Endocrinol. Metab. , vol.73 , pp. 781-784
    • Hubert, G.D.1    Schriock, E.D.2    Givens, J.R.3    Buster, J.E.4
  • 20
    • 0025321619 scopus 로고
    • Reduction in body weight and cholesterol in spontaneously obese dogs by dehydroepiandrosterone
    • Kurzman, I.D., MacEwen, E.G. and Haffa, A.L. (1989): Reduction in body weight and cholesterol in spontaneously obese dogs by dehydroepiandrosterone. Int. J. Obesity, 14, 95-104.
    • (1989) Int. J. Obesity , vol.14 , pp. 95-104
    • Kurzman, I.D.1    MacEwen, E.G.2    Haffa, A.L.3
  • 21
    • 0026457655 scopus 로고
    • Dehydroepiandrosterone sulfate, incidence of myocardial infarction, and extent of atherosclerosis in men
    • LaCroix, A.Z., Yano, K. and Reed, D.M. (1992): Dehydroepiandrosterone sulfate, incidence of myocardial infarction, and extent of atherosclerosis in men. Circulation, 86, 1529-1535.
    • (1992) Circulation , vol.86 , pp. 1529-1535
    • LaCroix, A.Z.1    Yano, K.2    Reed, D.M.3
  • 22
    • 0027469976 scopus 로고
    • Age and sex differences of dehydroepiandrosterone sulfate (DHEAS) and cortisol (CRT) plasma levels in normal controls and Alzheimer's disease (AD)
    • Leblhuber, F., Neubauer, C., Peichl, M., Reisecker, F., Steinparz, F.X., Winhager, E. and Dienstl, E. (1993): Age and sex differences of dehydroepiandrosterone sulfate (DHEAS) and cortisol (CRT) plasma levels in normal controls and Alzheimer's disease (AD). Psychopharmacology, 11, 23-26.
    • (1993) Psychopharmacology , vol.11 , pp. 23-26
    • Leblhuber, F.1    Neubauer, C.2    Peichl, M.3    Reisecker, F.4    Steinparz, F.X.5    Winhager, E.6    Dienstl, E.7
  • 23
    • 0028221213 scopus 로고
    • Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age
    • Morales, A.J., Nolan, J.J., Nelson, J.C. and Yen, S.S. (1994): Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. J. Clin. Endocrinol. Metab., 78, 1360-1367.
    • (1994) J. Clin. Endocrinol. Metab. , vol.78 , pp. 1360-1367
    • Morales, A.J.1    Nolan, J.J.2    Nelson, J.C.3    Yen, S.S.4
  • 24
    • 0025046185 scopus 로고
    • The effects of oral dehydroepiandrosterone on endocrine-metabolic parameters in post-menopausal women
    • Mortola, J.F. and Yen, S.S. (1990): The effects of oral dehydroepiandrosterone on endocrine-metabolic parameters in post-menopausal women. J. Clin. Endocrinol. Metab., 71, 696-704.
    • (1990) J. Clin. Endocrinol. Metab. , vol.71 , pp. 696-704
    • Mortola, J.F.1    Yen, S.S.2
  • 26
    • 0023838538 scopus 로고
    • Dehydroepiandrosterone reduces serum low density lipoprotein levels and body fat but does not alter insulin sensitivity in normal men
    • Nestler, J.E., Barlascini, C.O., Clore, J.N. and Blackard, W.G. (1988): Dehydroepiandrosterone reduces serum low density lipoprotein levels and body fat but does not alter insulin sensitivity in normal men. J. Clin. Endocrinol. Metab., 66, 57-61.
    • (1988) J. Clin. Endocrinol. Metab. , vol.66 , pp. 57-61
    • Nestler, J.E.1    Barlascini, C.O.2    Clore, J.N.3    Blackard, W.G.4
  • 28
    • 0026774274 scopus 로고
    • Dehydroepiandrosterone: The 'missing link' between hyperinsulinemia and atherosclerosis?
    • Nestler, J.E., Clore, J.N. and Blackard, W.G. (1992): Dehydroepiandrosterone: the 'missing link' between hyperinsulinemia and atherosclerosis? FASEB J., 6, 3073-3075.
    • (1992) FASEB J. , vol.6 , pp. 3073-3075
    • Nestler, J.E.1    Clore, J.N.2    Blackard, W.G.3
  • 29
    • 0028328225 scopus 로고
    • Effects of a reduction in circulating insulin by metformin on serum dehydroepiandrosterone sulfate in nondiabetic men
    • Nestler, J.E., Beer, N.A., Jakubowicz, D.J. and Beer, R.M. (1994): Effects of a reduction in circulating insulin by metformin on serum dehydroepiandrosterone sulfate in nondiabetic men. J. Clin. Endocrinol. Metab., 78, 549-554.
    • (1994) J. Clin. Endocrinol. Metab. , vol.78 , pp. 549-554
    • Nestler, J.E.1    Beer, N.A.2    Jakubowicz, D.J.3    Beer, R.M.4
  • 30
    • 0028835363 scopus 로고
    • Effects of insulin reduction with benfluorex on serum dehydroepiandrosterone (DHEA), DHEA sulfate, and blood pressure in hypertensive middle-aged and elderly men
    • Nestler, J.E., Beer, N.A., Jakubowikz, D.J., Colombo, C. and Beer, R.M. (1995): Effects of insulin reduction with benfluorex on serum dehydroepiandrosterone (DHEA), DHEA sulfate, and blood pressure in hypertensive middle-aged and elderly men. J. Clin. Endocrinol. Metab., 80, 700-706.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 700-706
    • Nestler, J.E.1    Beer, N.A.2    Jakubowikz, D.J.3    Colombo, C.4    Beer, R.M.5
  • 31
    • 0021181906 scopus 로고
    • Age and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulhood
    • Orentreich, N., Brind, J.L., Rizer, R.L. and Vogelman, J.H. (1984): Age and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulhood. J. Clin. Endocrinol. Metab., 59, 551-555.
    • (1984) J. Clin. Endocrinol. Metab. , vol.59 , pp. 551-555
    • Orentreich, N.1    Brind, J.L.2    Rizer, R.L.3    Vogelman, J.H.4
  • 32
    • 0026629845 scopus 로고
    • Long term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men
    • Orentreich, N., Brind, J.L., Vogelman, J.H., Andres, R. and Baldwin, H. (1992): Long term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men. J. Clin. Endocrinol. Metab., 75, 1002-1004.
    • (1992) J. Clin. Endocrinol. Metab. , vol.75 , pp. 1002-1004
    • Orentreich, N.1    Brind, J.L.2    Vogelman, J.H.3    Andres, R.4    Baldwin, H.5
  • 33
  • 34
    • 0022625980 scopus 로고
    • Responses of plasma adrenocorticotropin, cortisol, and dehydroepiandrosterone to ovine corticotropin-releasing hormone in healthy aging men
    • Pavlov, E.P., Harman, S.M., Chrousos, G.P., Loriaux, D.L. and Blackman, M.R. (1986): Responses of plasma adrenocorticotropin, cortisol, and dehydroepiandrosterone to ovine corticotropin-releasing hormone in healthy aging men. J. Clin. Endocrinol, Metab., 62, 767-772.
    • (1986) J. Clin. Endocrinol, Metab. , vol.62 , pp. 767-772
    • Pavlov, E.P.1    Harman, S.M.2    Chrousos, G.P.3    Loriaux, D.L.4    Blackman, M.R.5
  • 35
    • 0026638358 scopus 로고
    • Hepatocarcinogenicity of dehydroepiandrosterone in the rat
    • Rao, M.S., Subbarao, V., Yeldandi, A.V. and Reddy, J.K. (1992): Hepatocarcinogenicity of dehydroepiandrosterone in the rat. Cancer Res., 52, 2977-2979.
    • (1992) Cancer Res. , vol.52 , pp. 2977-2979
    • Rao, M.S.1    Subbarao, V.2    Yeldandi, A.V.3    Reddy, J.K.4
  • 36
    • 0029862990 scopus 로고    scopus 로고
    • The relationship of dehydroepiandrosterone sulfate (DHEAS) to endocrine-metabolic parameters and functional status in the oldest-old
    • Results from an italian study on healthy free-living over-ninety-year-olds
    • Ravaglia, G., Forti P., Maioli, F., Boschi, F., Bernardi, M., Pratelli, L., Pizzoferrato, A. and Gasbarrini, G. (1996): The relationship of dehydroepiandrosterone sulfate (DHEAS) to endocrine-metabolic parameters and functional status in the oldest-old. Results from an italian study on healthy free-living over-ninety-year-olds. J. Clin. Endocrinol. Metab., 81, 1173-1178.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 1173-1178
    • Ravaglia, G.1    Forti, P.2    Maioli, F.3    Boschi, F.4    Bernardi, M.5    Pratelli, L.6    Pizzoferrato, A.7    Gasbarrini, G.8
  • 37
    • 0028309503 scopus 로고
    • Dehydroepiandrosterone (DHEA) - The multifunctional steroid. II. Effects on the CNS, cell proliferation, metabolic and vascular, clinical and other effects. Mechanism of action?
    • Regelson, W. and Kalimi, M. (1994): Dehydroepiandrosterone (DHEA) - the multifunctional steroid. II. Effects on the CNS, cell proliferation, metabolic and vascular, clinical and other effects. Mechanism of action? Ann. N.Y. Acad. Sci., 719, 564-575.
    • (1994) Ann. N.Y. Acad. Sci. , vol.719 , pp. 564-575
    • Regelson, W.1    Kalimi, M.2
  • 38
    • 0028309696 scopus 로고
    • Dehydroepiandrosterone (DHEA) the 'mother steroid'. I. Immunologic action
    • Regelson, W., Loria, R. and Kalimi, M. (1994): Dehydroepiandrosterone (DHEA) the 'mother steroid'. I. Immunologic action. Ann. N.Y. Acad. Sci., 719, 553-563.
    • (1994) Ann. N.Y. Acad. Sci. , vol.719 , pp. 553-563
    • Regelson, W.1    Loria, R.2    Kalimi, M.3
  • 39
    • 0023126569 scopus 로고
    • Effects of dehydroepiandrosterone and its sulfate on brain tissue in culture and on memory in mice
    • Roberts, E., Bologa, L., Flood, J.F. and Smith, G.E. (1987): Effects of dehydroepiandrosterone and its sulfate on brain tissue in culture and on memory in mice. Brain Res., 40, 357-362.
    • (1987) Brain Res. , vol.40 , pp. 357-362
    • Roberts, E.1    Bologa, L.2    Flood, J.F.3    Smith, G.E.4
  • 40
    • 0025280117 scopus 로고
    • Age, steroids and bone mineral content
    • Rozenberg, S., Ham, H. and Bosson, D. (1990): Age, steroids and bone mineral content. Maturitas, 12, 137-143.
    • (1990) Maturitas , vol.12 , pp. 137-143
    • Rozenberg, S.1    Ham, H.2    Bosson, D.3
  • 41
    • 0025960178 scopus 로고
    • The relationship between sex steroids and bone mineral content in women soon after menopause
    • Spector, T.D., Thompson, P.W., Perry, L.A., McGarrigle, H.H. and Edwards, A.C. (1991): The relationship between sex steroids and bone mineral content in women soon after menopause. Clin. Endocrinol., 34, 37-41.
    • (1991) Clin. Endocrinol. , vol.34 , pp. 37-41
    • Spector, T.D.1    Thompson, P.W.2    Perry, L.A.3    McGarrigle, H.H.4    Edwards, A.C.5
  • 45
    • 0025085978 scopus 로고
    • Failure of dehydroepiandrosterone to influence energy and protein metabolism in humans
    • Welle, S., Jozefowicz, R. and Statt, M. (1990): Failure of dehydroepiandrosterone to influence energy and protein metabolism in humans. J. Clin. Endocrinol. Metab., 71, 1259-1264.
    • (1990) J. Clin. Endocrinol. Metab. , vol.71 , pp. 1259-1264
    • Welle, S.1    Jozefowicz, R.2    Statt, M.3
  • 46
    • 0026073142 scopus 로고
    • Suppressive effects of dehydroepiandrosterone and 3b-methyl-androst-5-en-17-one on attack towards lactating female intruders by castrated male mice. II. Brain steroids
    • Young, J., Corpechot, C., Haug, M., Gobaille, S., Baulieu, E.E. and Robel, P. (1991): Suppressive effects of dehydroepiandrosterone and 3b-methyl-androst-5-en-17-one on attack towards lactating female intruders by castrated male mice. II. Brain steroids. Biochem. Biophys. Res. Commun., 174, 892-897.
    • (1991) Biochem. Biophys. Res. Commun. , vol.174 , pp. 892-897
    • Young, J.1    Corpechot, C.2    Haug, M.3    Gobaille, S.4    Baulieu, E.E.5    Robel, P.6
  • 47
    • 0019513506 scopus 로고
    • Abnormal 24 hour mean plasma concentrations dehydroepiandrosterone and dehydroepiandrosterone sulfate in women with primary operable breast cancer
    • Zumoff, B., Levin, J., Rosenfeld, R.S., Markham, M., Strain, G.W. and Fukushima, D.K. (1981): Abnormal 24 hour mean plasma concentrations dehydroepiandrosterone and dehydroepiandrosterone sulfate in women with primary operable breast cancer. Cancer Res., 41, 3360-3363.
    • (1981) Cancer Res. , vol.41 , pp. 3360-3363
    • Zumoff, B.1    Levin, J.2    Rosenfeld, R.S.3    Markham, M.4    Strain, G.W.5    Fukushima, D.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.