Role of p53 mutation in polyomavirus-induced tumorigenesis

Journal of General Virology

Volumn 78, Issue 4, 1997, Pages 893-903

  Qian, Wang ^a   Kashuba, Elena ^a   Magnusson, Kristinn P ^a   Pokrovskaja, Katja ^a   Okan, Ismail ^a   Klein, George ^a   Wiman, Klas G ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MESSENGER RNA; MITOMYCIN C; MUTANT PROTEIN; PROTEIN P21; PROTEIN P53; REGULATOR PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; GENE INDUCTION; GENE MUTATION; IMMUNOFLUORESCENCE TEST; MOUSE; NONHUMAN; NORTHERN BLOTTING; POLYOMA VIRUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARCOMA; TRANSACTIVATION; TUMOR SUPPRESSOR GENE; VIRUS CARCINOGENESIS;

EID: 0030932067     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-78-4-893     Document Type: Article

References (55)

1. Asselin, C. & Bastin, M. (1985). Sequences from polyomavirus and simian virus 40 large T genes capable of immortalizing primary rat embryo fibroblasts. Journal of Virology 56, 958-968.
2. Asselin, C., Gelinas, C. & Bastin, M. (1983). Role of the three polyomavirus early proteins in tumorigenesis. Molecular and Cellular Biology 3, 1451-1459.
3. Asselin, C., Vass-Marego, J. & Bastin, M. (1986). Mutation in the polyomavirus genome that activates the properties of large T associated with neoplastic transformation. Journal of Virology 57, 165-172.
4. Barak, Y., Gottlieb, E., Juven-Gershon, T. & Oren, M. (1994). Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translational potential. Genes & Development 8, 1739-1749.
5. Chomczynski, P. & Sacchi, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analytical Biochemistry 162, 156-159.
6. Cowie, A., de Villiers, J. & Kamen, R. (1986). Immortalization of rat embryo fibroblasts by mutant polyomavirus large T antigen deficient in DNA binding. Molecular and Cellular Biology 6, 4344-4352.
7. Debbas, M. & White, E. (1993). Wild type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes & Development 7, 546-554.
8. DeCaprio, J. A., Ludlow, J. W., Figge, J., Shew, J. Y., Huang, C. M., Lee, W. H., Marsilio, E., Paucha, E. & Livingston, D. M. (1988). SV40 large T tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell 54, 275-283.
9. Deng, C., Zhang, P., Harper, J. W., Elledge, S. J. & Leder, P. (1995). Mice lacking p21-CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 82, 675-684.
10. de Oca Luna, R. M., Wagner, D. S. & Lozano, G. (1995). Rescue of early embryonic lethality in mdm-2 deficient mice by deletion of p53. Nature 378, 203-206.
11. Depamphilis, M. L. & Bradley, M. K. (1986). Replication of SV40 and polyoma virus chromosomes. In The Papovaviridae, vol. 1, pp. 99-244. Edited by N. P. Salzman. New York: Plenum.
12. Dilworth, S. M. (1995). Polyoma virus middle T antigen: meddler or mimic? Trends in Microbiology 3, 31-35.
13. Donehower, L. A., Harvey, M., Slagle, B. L., McArthur, M. J., Montgomery, C. A., Jr, Butel, J. S. & Bradley, A. (1992). Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors. Nature 356, 215-221.
14. Dooley, S., Ehrhart, E., Radtke, J., Unteregger, G. & Blin, N. (1989). A procedure for simultaneous isolation of undegraded RNA, DNA and nuclear proteins suitable for interaction analysis in homologous systems. Methods in Molecular and Cellular Biology 1, 95-105.
15. Dyson, N., Bernards, R., Friend, S. H., Gooding, L. R., Hassell, J. A., Major, E. O., Pipas, J. M., Van Dyke, T. & Harlow, E. (1990). Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein. Journal of Virology 64, 1353-1356.
16. Fakharzadeh, S. S., Trusko, S. P. & George, D. L. (1991). Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line. EMBO Journal 10, 1565-1569.
17. Finlay, C. A. (1993). The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth. Molecular and Cellular Biology 13, 301-306.
18. Freund, R., Bronson, R. T. & Benjamin, T. L. (1992). Separation of immortalization from tumor induction with polyoma large T mutants that fail to bind the retinoblastoma gene product. Oncogene 7, 1979-1987.
19. Freund, R., Bauer, P. H., Crissman, H. A., Bradbury, E. M. & Benjamin, T. L. (1994). Host range and cell cycle activation of properties of polyomavirus large T-antigen mutants defective in pRB binding. Journal of Virology 68, 7227-7234.
20. Fritsche, M., Haessler, C. & Brandner, G. (1993). Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents. Oncogene 8, 307-318.
21. Graeber, T. G., Osmanian, C., Jacks, T., Housman, D. E., Koch, C. J., Lowe, S. W. & Giaccia, A. J. (1996). Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumors. Nature 379, 88-91.
22. Greenblatt, M. S., Bennett, W. P., Hollstein, M. & Harris, C. C. (1994). Mutations in the p53 tumor suppressor gene : clues to cancer etiology and molecular pathogenesis. Cancer Research 54, 4855-4878.
23. Grodzicker, T. & Hopkins, N. (1981). Origins of contemporary DNA tumor virus research. In DNA Tumor Viruses: Molecular Biology of Tumor Viruses, pp. 7-8. Edited by J. Tooze. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
24. Hermeking, H. & Eick, D. (1994). Mediation of c-Myc-induced apoptosis by p53. Science 265, 2091-2093.
25. Hultman, T., Bergh, S., Moks, T. & Uhlén, M. (1991). Bidirectional solid phase sequencing of in vitro amplified plasmid DNA. BioTechniques 10, 84-93.
26. Jat, P. S. & Sharp, P. A. (1986). Large T antigens of simian virus 40 and polyomavirus efficiently establish primary fibroblasts. Journal of Virology 59, 746-750.
27. Jones, S. N., Roe, A. E., Donehower, L. A. & Bradley, A. (1995). Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature 378, 206-208.
28. Kastan, M. B., Onyekwere, O., Sidransky, D., Vogelstein, B. & Craig, R. W. (1991). Participation of p53 protein in the cellular response to DNA damage. Cancer Research 51, 6304-6311.
29. Ko, L. J. & Prives, C. (1996). p53: puzzle and paradigm. Genes & Development 10, 1054-1072.
30. Larose, A., Dyson, N., Sullivan, M., Harlow, E. & Bastin, M. M. (1991). Polyomavirus large T mutants affected in retinoblastoma protein binding are defective in immortalization. Journal of Virology 65, 2308-2313.
31. Levine, A. J. (1990). The p53 protein and its interactions with the oncogene products of the small DNA tumor viruses. Virology 177, 419-426.
32. Lin, J. Y. & Simmons, D. T. (1991). The ability of large T antigen to complex with p53 is necessary for the increased life span and partial transformation of human cells by simian virus 40. Journal of Virology 65, 6447-6453.
33. Lowe, S. W., Jacks, T., Housman, D. E. & Ruley, H. E. (1994). Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells. Proceedings of the National Academy of Sciences, USA 91, 2026-2030.
34. Magnusson, K. P., Minarovits, J., Klein, G. & Wiman, K. G. (1995). A splice donor site mutation results in the insertion of five extra amino acids into p53 from SEWA mouse sarcoma cells. Gene 162, 231-234.
35. Maltzman, W. & Czyzyk, L. (1984). UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells. Molecular and Cellular Biology 4, 1689-1694.
36. Michieli, P., Chedid, M., Lin, D., Pierce, J. H., Mercer, W. E. & Givol, D. (1994). Induction of WAF1/CIP1 by a p53-independent pathway. Cancer Research 54, 3391-3395.
37. Oliner, J. D., Kinzler, K. W., Meltzer, D. L., George, D. L. & Vogelstein, B. (1992). Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 358, 80-83.
38. Oliner, J. D., Pietenpol, J. A., Thiagalingams, S., Gyuris, J., Kinzler, K. W. & Vogelstein, B. (1993). Oncoprotein MDM2 conceals the activation domain of tumor suppressor p53. Nature 362, 857-860.
39. Parker, S. B., Eichele, G., Zhang, P., Rawls, A., Sands, A. T., Bradley, A., Olson, E. N., Harper, J. W. & Elledge, S. J. (1995). p53-independent expression of p21-Cip1 in muscle and other terminally differentiating cells. Science 267, 1024-1027.
40. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989). Analysis and cloning of eukaryotic genomic DNA. In Molecular Cloning: A Laboratory Manual, 2nd edn, pp. 9.16-9.19. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
41. Selivanova, G. & Wiman, K. G. (1995). p53: a cell cycle regulator activated by DNA damage. Advances in Cancer Research 66, 143-180.
42. Soeda, E., Arrand, J. R., Smolar, N., Walsh, J. E. & Griffin, B. E. (1980). Coding potential and regulatory signals of the polyoma virus genome. Nature 283, 445-453.
43. Topp, W. C., Lane, D. P. & Poolack, R. (1981). Transformation by simian virus 40 & polyoma virus. In DNA Tumor Viruses: Molecular Biology of Tumor Viruses, pp. 206-207. Edited by J. Tooze. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
44. Treisman, R., Noval, U., Favaloro, J. & Kamen, R. (1981). Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein. Nature 292, 595-600.
45. Turler, H. (1980). The tumor antigens and the early functions of polyoma virus. Molecular and Cellular Biology 32, 63-93.
46. Villareal, L. P. & Fan, H. (1989). History and biological strategy of polyomavirus, adenovirus and papillomavirus. In Common Mechanisms of Transformation by Small DNA Tumor Viruses, pp. 1-17. Edited by L. P. Villareal. Washington, DC: American Society for Microbiology.
47. Voss H., Wiemann, S., Wirkner, S., Schwager, C., Zimmermann, J., Stegemann, J., Erfle, H., Hewitt, N. A., Rupp, T. & Ansorge, W. (1992). Automated DNA sequencing system resolving 1000 bases with fluorescein-15*dATP as internal label. Methods in Molecular and Cellular Biology 3, 153-155.
48. Wagner, A. J., Kokontis, J. M. & Hay, N. (1994). Myc-mediated apoptosis requires wild type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21-Waf1/Cip1. Genes & Development 8, 2817-2830.
49. Waldman, T., Kinzler, K. W. & Vogelstein, B. (1995). p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Research 55, 5187-5190.
50. Wang, E. H., Friedman, P. N. & Prives, C. (1989). The murine p53 protein blocks replication of SV40 DNA in vitro by inhibiting the initiation functions of SV40 large T antigen. Cell 57, 379-392.
51. Warburg, O. & Hiepler, E. (1952). Versuche mit Ascites-Tumorzellen. Zeitschrift für Naturforschung Section B Chemical Sciences 7, 193-194.
52. Weinberg, R. A. (1995). The retinoblastoma protein and cell cycle control. Cell 81, 323-330.
53. Williams, C. A. & Krawisz, B. R. (1989). Aurintricarboxylic acid as a ribonuclease inhibitor. Methods in Molecular and Cellular Biology 1, 35-40.
54. Wiman, K. G., Magnusson, K. P., Ramqvist, T. & Klein, G. (1991). Mutant p53 detected in a majority of Burkitt lymphoma cell lines by monoclonal antibody PAb240. Oncogene 6, 1633-1639.
55. Wu, X., Bayle, J. H., Olson, D. & Levine, A. J. (1993). The p53-mdm-2 auto-regulatory feedback loop. Genes & Development 7, 1126-1132.