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Volumn 24, Issue 4, 1997, Pages 170-174

Neurotrophic factors in the treatment of neurologic diseases;Neurotrophe faktoren in der therapie neurologischer erkrankungen

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CILIARY NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; NEUROTROPHIN 3; SOMATOMEDIN C;

EID: 0030931528     PISSN: 03024350     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-1017804     Document Type: Article
Times cited : (1)

References (42)
  • 1
    • 15844381714 scopus 로고    scopus 로고
    • Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients
    • Aebischer, P., M. Schluep, N. Deglon, et al.: Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients. Nature Med. 2 (1996) 696-699
    • (1996) Nature Med. , vol.2 , pp. 696-699
    • Aebischer, P.1    Schluep, M.2    Deglon, N.3
  • 2
    • 0345509278 scopus 로고
    • Recombinant human ciliary neurotrophic factor (rhCNTF) in amyotrophic lateral sclerosis (ALS) patients: Phase I-II safety, tolerability and pharmacokinetic studies
    • ALS CNTF Treatment Study (ACTS): Recombinant human ciliary neurotrophic factor (rhCNTF) in amyotrophic lateral sclerosis (ALS) patients: Phase I-II safety, tolerability and pharmacokinetic studies (abstract). Neurology 43 (1993) A416
    • (1993) Neurology , vol.43
  • 3
    • 0028788303 scopus 로고
    • A phase 1 study of recombinant human ciliary neurotrophic factor (rHCNTF) in patients with amyotrophic lateral sclerosis
    • ALS CNTF Treatment Study (ACTS): A phase 1 study of recombinant human ciliary neurotrophic factor (rHCNTF) in patients with amyotrophic lateral sclerosis. Clin. Neuropharmacol. 18 (1995) 515-532
    • (1995) Clin. Neuropharmacol. , vol.18 , pp. 515-532
  • 4
    • 2442646665 scopus 로고    scopus 로고
    • A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis
    • ALS CNTF Treatment Study (ACTS): A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. Neurology 46 (1996) 1244-1249
    • (1996) Neurology , vol.46 , pp. 1244-1249
  • 5
    • 0028883432 scopus 로고
    • Neurotrophic factors in the therapy of peripheral neuropathy
    • Apfel, S. C., J. A. Kessler.: Neurotrophic factors in the therapy of peripheral neuropathy. Bailliere's Clin. Neurol. 4 (1995) 593-606
    • (1995) Bailliere's Clin. Neurol. , vol.4 , pp. 593-606
    • Apfel, S.C.1    Kessler, J.A.2
  • 6
    • 0025514410 scopus 로고
    • Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: Comparison with other neurotrophic factors and cytokines
    • Arakawa, Y., M. Sendtner, H. Thoenen: Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines. J. Neurosci. 10 (1990) 3507-3515
    • (1990) J. Neurosci. , vol.10 , pp. 3507-3515
    • Arakawa, Y.1    Sendtner, M.2    Thoenen, H.3
  • 7
    • 0000337980 scopus 로고
    • The BDNF Trial Group: A phase I/II study of recombinant human brain-derived neurotrophic factor in patients with amyotrophic lateral sclerosis
    • Bradley, W. G.: The BDNF Trial Group: A phase I/II study of recombinant human brain-derived neurotrophic factor in patients with amyotrophic lateral sclerosis. Ann. Neurol. 38 (1995) 971
    • (1995) Ann. Neurol. , vol.38 , pp. 971
    • Bradley, W.G.1
  • 8
    • 0025234804 scopus 로고
    • Nerve sprouting in innervated adult skeletal muscle induced by exposure to elevated levels of insulin-like growth factors
    • Caroni, P., P. Grandes: Nerve sprouting in innervated adult skeletal muscle induced by exposure to elevated levels of insulin-like growth factors. J. Cell Biol. 110 (1990) 1307-1317
    • (1990) J. Cell Biol. , vol.110 , pp. 1307-1317
    • Caroni, P.1    Grandes, P.2
  • 9
    • 0029869593 scopus 로고    scopus 로고
    • Selective activation of NF- kappa B by nerve growth factor through the neurotrophin receptor p75
    • Carter, B. D., C. Kaltschmidt, B. Kaltschmidt et al.: Selective activation of NF- kappa B by nerve growth factor through the neurotrophin receptor p75. Science 272 (1996) 542-545
    • (1996) Science , vol.272 , pp. 542-545
    • Carter, B.D.1    Kaltschmidt, C.2    Kaltschmidt, B.3
  • 10
    • 0007101117 scopus 로고    scopus 로고
    • Pharmacokinctics of intrathecally applied BDNF and effects on spinal motoneurons
    • Dittrich, F., G. Ochs, A. Grosse-Wilde et al.: Pharmacokinctics of intrathecally applied BDNF and effects on spinal motoneurons. Exp. Neurol. 141 (1996) 225-239
    • (1996) Exp. Neurol. , vol.141 , pp. 225-239
    • Dittrich, F.1    Ochs, G.2    Grosse-Wilde, A.3
  • 11
    • 0028137577 scopus 로고
    • Ciliary neurotrophic factor: Pharmacokinetics and acute-phase response in rat
    • Dittrich, F., H. Thoenen, M. Sendtner: Ciliary neurotrophic factor: Pharmacokinetics and acute-phase response in rat. Ann. Neurol. 35 (1994) 151-163
    • (1994) Ann. Neurol. , vol.35 , pp. 151-163
    • Dittrich, F.1    Thoenen, H.2    Sendtner, M.3
  • 12
    • 0028291238 scopus 로고
    • Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents
    • Ernfors, P., K. Lee, J. Kucera et al.: Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents. Cell 77 (1994) 503-512.
    • (1994) Cell , vol.77 , pp. 503-512
    • Ernfors, P.1    Lee, K.2    Kucera, J.3
  • 13
    • 0029978443 scopus 로고    scopus 로고
    • Cell-mediated delivery of brain-derived neurotrophic factor enhances dopamine levels in an MPP+ rat model of substantia nigra degeneration
    • Galpern, W. R., D. M. Frim, S. B. Tatter et al.: Cell-mediated delivery of brain-derived neurotrophic factor enhances dopamine levels in an MPP+ rat model of substantia nigra degeneration. Cell Transplant 5 (1996) 225-232
    • (1996) Cell Transplant , vol.5 , pp. 225-232
    • Galpern, W.R.1    Frim, D.M.2    Tatter, S.B.3
  • 14
    • 0026667103 scopus 로고
    • Induction of motor neuron sprouting in vivo by ciliary neurotrophic factor and basic fibroblast growth factor
    • Gurney, M. E., H. Yamamoto, Y. Kwon: Induction of motor neuron sprouting in vivo by ciliary neurotrophic factor and basic fibroblast growth factor. J. Neurosci. 12 (1992) 3241-3247
    • (1992) J. Neurosci. , vol.12 , pp. 3241-3247
    • Gurney, M.E.1    Yamamoto, H.2    Kwon, Y.3
  • 15
    • 0028307157 scopus 로고
    • Systemic administration of ciliary neurotrophic factor induces cachexia in rodents
    • Henderson, J. T., N. A. Seniuk, P. M. Richardson et al.: Systemic administration of ciliary neurotrophic factor induces cachexia in rodents. J. Clin. Invest. 93 (1994) 2632-2638
    • (1994) J. Clin. Invest. , vol.93 , pp. 2632-2638
    • Henderson, J.T.1    Seniuk, N.A.2    Richardson, P.M.3
  • 16
    • 0027131764 scopus 로고
    • Members of several gene families influence survival of rat motoneurons in vitro and in vivo
    • Hughes, R. A., M. Sendtner, H. Thoenen: Members of several gene families influence survival of rat motoneurons in vitro and in vivo. J. Neurosci. Res. 36 (1993) 663-671
    • (1993) J. Neurosci. Res. , vol.36 , pp. 663-671
    • Hughes, R.A.1    Sendtner, M.2    Thoenen, H.3
  • 17
    • 0028916844 scopus 로고
    • Effects of brain-derived neurotrophic factor on motor dysfunction Wobbler mouse motor neuron disease
    • Ikeda, K., B. Klinkosz, T. Greene et al: Effects of brain-derived neurotrophic factor on motor dysfunction Wobbler mouse motor neuron disease. Ann. Neurol. 37 (1995) 505-511
    • (1995) Ann. Neurol. , vol.37 , pp. 505-511
    • Ikeda, K.1    Klinkosz, B.2    Greene, T.3
  • 18
    • 0029916808 scopus 로고    scopus 로고
    • Liposome-mediated BDNF cDNA transfer in intact and injured rat brain
    • Iwamoto, Y., K. Yang, G. L. Clifton et al.: Liposome-mediated BDNF cDNA transfer in intact and injured rat brain. Neuroreport 7 (1996) 609-612
    • (1996) Neuroreport , vol.7 , pp. 609-612
    • Iwamoto, Y.1    Yang, K.2    Clifton, G.L.3
  • 19
    • 0024391282 scopus 로고
    • Insulin-like growth factor I (IGF-I) stimulates regeneration of the rat sciatic nerve
    • Kanje, M., A. Skottner, J. Sjoberg et al.: Insulin-like growth factor I (IGF-I) stimulates regeneration of the rat sciatic nerve. Brain Res. 486 (1989) 396-398
    • (1989) Brain Res. , vol.486 , pp. 396-398
    • Kanje, M.1    Skottner, A.2    Sjoberg, J.3
  • 20
    • 0011849128 scopus 로고
    • A double-blind, placebo-controlled study of recombinant human insulin-like growth factor in the treatment of amyotrophic lateral sclerosis
    • Lai, E. C., K. Felice, B. W. Festoff et al.: A double-blind, placebo-controlled study of recombinant human insulin-like growth factor in the treatment of amyotrophic lateral sclerosis. Ann. Neurol. 38 (1995) 971
    • (1995) Ann. Neurol. , vol.38 , pp. 971
    • Lai, E.C.1    Felice, K.2    Festoff, B.W.3
  • 21
    • 0347686420 scopus 로고
    • A double-blind, placebo-controlled therapeutic trial to assess the efficacy of recombinant human insulin-like growth hormone
    • Dublin
    • Lange, D. J., K. J. Felice, M. J. Grewal et al.: A double-blind, placebo-controlled therapeutic trial to assess the efficacy of recombinant human insulin-like growth hormone (abstract). 6th International Symposium on ALS/MND, Dublin 30.10.-1.11.1995
    • (1995) 6th International Symposium on ALS/MND , pp. 3010-3111
    • Lange, D.J.1    Felice, K.J.2    Grewal, M.J.3
  • 22
    • 0026462896 scopus 로고
    • Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light
    • LaVail, M. M., K. Unoki, D. Yasumura et al.: Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light. Proc. Natl. Acad. Sci. USA 89 (1992) 11249-11253
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 11249-11253
    • Lavail, M.M.1    Unoki, K.2    Yasumura, D.3
  • 23
    • 0028279370 scopus 로고
    • Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse
    • Li, L., R. W. Oppenheim, M. Lei et al.: Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse. J. Neurobiol. 25 (1994) 759-766
    • (1994) J. Neurobiol. , vol.25 , pp. 759-766
    • Li, L.1    Oppenheim, R.W.2    Lei, M.3
  • 24
    • 0344596271 scopus 로고
    • Safety, tolerability and pharmacokinetics of recombinant human ciliary neurotrophic factor (rhCNTF) in patients with amyotrophic lateral sclerosis
    • Miller, R. G., W. W. Bryan, M. Dietz et al.: Safety, tolerability and pharmacokinetics of recombinant human ciliary neurotrophic factor (rhCNTF) in patients with amyotrophic lateral sclerosis (abstract). Ann. Neurol. 34 (1993) 304
    • (1993) Ann. Neurol. , vol.34 , pp. 304
    • Miller, R.G.1    Bryan, W.W.2    Dietz, M.3
  • 25
    • 9044219848 scopus 로고    scopus 로고
    • A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis
    • Miller, R. G., J. H. Petajan, W. W. Bryan et al.: A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis. Ann. Neurol. 39 (1996) 256-260
    • (1996) Ann. Neurol. , vol.39 , pp. 256-260
    • Miller, R.G.1    Petajan, J.H.2    Bryan, W.W.3
  • 26
    • 0028027060 scopus 로고
    • Arrest of motor neuron disease in wobbler mice cotreated with CNTF and BDNF
    • Mitsumoto, H., K. Ikeda, B. Klinkosz et al.: Arrest of motor neuron disease in wobbler mice cotreated with CNTF and BDNF. Science 265 (1994) 1107-1110
    • (1994) Science , vol.265 , pp. 1107-1110
    • Mitsumoto, H.1    Ikeda, K.2    Klinkosz, B.3
  • 27
    • 0030052736 scopus 로고    scopus 로고
    • Intrastriatal and intraventricular infusion of brain-derived neurotrophic factor in the cynomologous monkey: Distribution, retrograde transport and colocalization with substantia nigra dopamine-containing neurons
    • Mufson, E. J., J. S. Kroin, Y. T. Liu et al.: Intrastriatal and intraventricular infusion of brain-derived neurotrophic factor in the cynomologous monkey: Distribution, retrograde transport and colocalization with substantia nigra dopamine-containing neurons. Neuroscience 71 (1996) 179-191
    • (1996) Neuroscience , vol.71 , pp. 179-191
    • Mufson, E.J.1    Kroin, J.S.2    Liu, Y.T.3
  • 28
    • 0029983422 scopus 로고    scopus 로고
    • Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord
    • Nakahara, Y., F. H. Gage, M. H. Tuszynski: Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord. Cell Transplant 5 (1996) 191-204
    • (1996) Cell Transplant , vol.5 , pp. 191-204
    • Nakahara, Y.1    Gage, F.H.2    Tuszynski, M.H.3
  • 29
    • 0027094145 scopus 로고
    • Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death
    • Oppenheim, R. W., Y. Qin Wei, D. Prevette et al.: Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death. Nature 360 (1992) 755-757
    • (1992) Nature , vol.360 , pp. 755-757
    • Oppenheim, R.W.1    Qin Wei, Y.2    Prevette, D.3
  • 30
    • 0000767210 scopus 로고
    • An overview of the clinical experience with systematic administration of nerve growth factor in treating peripheral nervous system disorders
    • Rask, C., S. C. Apfel, B. T. Adornato et al.: An overview of the clinical experience with systematic administration of nerve growth factor in treating peripheral nervous system disorders. Ann. Neurol. 38 (1995) 317
    • (1995) Ann. Neurol. , vol.38 , pp. 317
    • Rask, C.1    Apfel, S.C.2    Adornato, B.T.3
  • 31
    • 0029005234 scopus 로고
    • CNTF variants with increased biological potency and receptor selectivity define a functional site of receptor interaction
    • Saggio, I., I. Gloaguen, G. Poiana et al.: CNTF variants with increased biological potency and receptor selectivity define a functional site of receptor interaction. Embo J. 14 (1995) 3045-3054
    • (1995) Embo J. , vol.14 , pp. 3045-3054
    • Saggio, I.1    Gloaguen, I.2    Poiana, G.3
  • 32
    • 0029077018 scopus 로고
    • Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuronopathy in the mouse
    • Sagot, Y., S. A. Tan, E. Baetge et al.: Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuronopathy in the mouse. Eur. J. Neurosci. 7 (1995) 1313-1322
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 1313-1322
    • Sagot, Y.1    Tan, S.A.2    Baetge, E.3
  • 33
    • 0028016137 scopus 로고
    • CNTF potentiates peripheral nerve regeneration
    • Sahenk, Z., J. Seharaseyon, J. R. Mendell: CNTF potentiates peripheral nerve regeneration. Brain Res. 655 (1994) 246-250
    • (1994) Brain Res. , vol.655 , pp. 246-250
    • Sahenk, Z.1    Seharaseyon, J.2    Mendell, J.R.3
  • 34
    • 0028839237 scopus 로고
    • Molecular biology of neurotrophic factors
    • Sendtner, M.: Molecular biology of neurotrophic factors. Bailliere's Clin. Neurol. 4 (1995) 575-591
    • (1995) Bailliere's Clin. Neurol. , vol.4 , pp. 575-591
    • Sendtner, M.1
  • 35
    • 0027070473 scopus 로고
    • Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section
    • Sendtner, M., B. Holtmann, R. Kolbeck et al.: Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 360 (1992) 757-759
    • (1992) Nature , vol.360 , pp. 757-759
    • Sendtner, M.1    Holtmann, B.2    Kolbeck, R.3
  • 36
    • 0025325548 scopus 로고
    • Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy
    • Sendtner, M., G. W. Kreutzberg, H. Thoenen: Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature 345 (1990) 440-441
    • (1990) Nature , vol.345 , pp. 440-441
    • Sendtner, M.1    Kreutzberg, G.W.2    Thoenen, H.3
  • 37
    • 0026749255 scopus 로고
    • Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy
    • Sendtner, M., H. Schmalbruch, K. A. Stöckli et al.: Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature 358 (1992) 502 -504
    • (1992) Nature , vol.358 , pp. 502-504
    • Sendtner, M.1    Schmalbruch, H.2    Stöckli, K.A.3
  • 38
    • 0026694239 scopus 로고
    • Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration
    • Sendtner, M., K. A. Stöckli, H. Thoenen: Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration. J. Cell Biol. 118 (1992) 139-148
    • (1992) J. Cell Biol. , vol.118 , pp. 139-148
    • Sendtner, M.1    Stöckli, K.A.2    Thoenen, H.3
  • 39
    • 0029134998 scopus 로고
    • NT-3 combined with CNTF promotes survival of neurons in modiolus-spiral ganglion explants
    • Staecker, H., W. Liu, C. Hartnick et al.: NT-3 combined with CNTF promotes survival of neurons in modiolus-spiral ganglion explants. Neuroreport 6 (1995) 1533-1537
    • (1995) Neuroreport , vol.6 , pp. 1533-1537
    • Staecker, H.1    Liu, W.2    Hartnick, C.3
  • 40
    • 0027756168 scopus 로고
    • Trophic support of motoneurons: Physiological, pathophysiological, and therapeutic implications
    • Thoenen, H., R. A. Hughes, M. Sendtner: Trophic support of motoneurons: Physiological, pathophysiological, and therapeutic implications. Exp. Neurol. 124 (1993) 47-55
    • (1993) Exp. Neurol. , vol.124 , pp. 47-55
    • Thoenen, H.1    Hughes, R.A.2    Sendtner, M.3
  • 41
    • 0029114190 scopus 로고
    • Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult
    • Tomac, A., J. Widenfalk, L. Lin et al.: Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult. Proc. Natl. Acad. Sci. USA 92 (1995) 8274-8278
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8274-8278
    • Tomac, A.1    Widenfalk, J.2    Lin, L.3
  • 42
    • 0028289716 scopus 로고
    • Distribution of intracerebral ventricularly administered neurotrophins in rat brain and its correlation with trk receptor expression
    • Yan, Q., C. Matheson, J. Sun et al.: Distribution of intracerebral ventricularly administered neurotrophins in rat brain and its correlation with trk receptor expression. Exp. Neurol. 127 (1994) 23-36
    • (1994) Exp. Neurol. , vol.127 , pp. 23-36
    • Yan, Q.1    Matheson, C.2    Sun, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.