Osteopontin, a coordinator of host defense system: A cytokine or an extracellular adhesive protein?

Microbiology and Immunology

Volumn 41, Issue 9, 1997, Pages 641-648

  Uede, Toshimitsu ^a   Katagiri, Yohko ^a   Iizuka, Junko ^a   Murakami, Masaaki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Autoimmunity; B1 cells; CD44; Early T lymphocyte activation 1; Integrin; Osteopontin; RGD tripeptide sequence; Tumor metastasis

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; CELL SURFACE RECEPTOR; CYTOKINE; HERMES ANTIGEN; INTEGRIN; OSTEOPONTIN;

AMINO ACID SEQUENCE; AUTOIMMUNITY; BINDING SITE; CARDIOVASCULAR SYSTEM; CELL ADHESION; CELL MIGRATION; GENE EXPRESSION; HOST RESISTANCE; IMMUNE SYSTEM; METASTASIS; PROTEIN ANALYSIS; PROTEIN STRUCTURE; RECEPTOR BINDING; SHORT SURVEY; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; URINARY TRACT;

EID: 0030930807     PISSN: 03855600     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1348-0421.1997.tb01906.x     Document Type: Short Survey

References (61)

1. Anderson, G., and Jennische, E. 1988. IGF-I immunoreactivity is expressed by regenerating renal tubular cells after ischemic injury in the rat. Acta Physiol. Scand. 132: 453-457.
2. Aruffo, A., Stamenkovic, I., Melnick, M., Underhill, C.B., and Seed, B. 1990. CD44 is the principal cell surface receptor for hyaluronate. Cell 61: 1303-1313.
3. Belin, M.T., and Boulanger, P. 1994. Involvement of cellular adhesion sequences in the attachment of adenovirus to the HeLa cell surface. J. Gen. Virol. 74: 1485-1497.
4. Behrend, E.I., Craig, A.M., Wilson, S.M., Denhardt, D.T., and Chambers, A.F. 1994. Reduced malignancy of ras-transformed NIH 3T3 cells expressing antisense osteopontin RNA. Cancer Res. 54: 832-837.
5. Brooks, P.C., Montgomery, A.M.P., Rossenfeld, M., Reisfeld, R.A., Hu, T., Klien, G., and Cheresh, D.A. 1994. Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79: 1157-1164.
6. Brown, L.F., Berse, B., Van De Water, L., Papadopoulos-Sergiou, A., Perruzzi, C.A., Manseau, E.J., Dvorak, H.F., and Senger, D.R. 1992. Expression and distribution of osteopontin in human tissues: widespread association with luminal epithelial surfaces. Mol. Biol. Cell 3: 1169-1180.
7. Butler, W.T. 1989. The nature and significance of osteopontin. Connect. Tissue Res. 23: 123-126.
8. Chambers, A.F., Hota, C., and Prince, C.W. 1993. Adhesion of metastatic, ras-transformed NIH 3T3 cells to osteopontin, fibronectin, and laminin. Cancer Res. 53: 701-706.
9. Chen, J., Singh, K., Mukherjee, B.B., and Sodek, J. 1993. Developmental expression of osteopontin (OPN) mRNA in rat tissues: evidence for a role for OPN in bone formation and resorption. Matrix 13: 113-123.
10. Craig, A.M., Smith, J.H., and Denhardt, D.T. 1989. Osteopontin, a transformation-associated cell adhesion phosphoprotein, is induced by 12-O-tetradecanoylphorbol 13-acetate in mouse epidermis. J. Biol. Chem. 264: 9682-9689.
11. Feng, B., Rollow, E.E., and Denhardt, D.T. 1995. Osteopontin (OPN) may facilitate metastasis by protecting cells from macrophage NO-mediated cytotoxicity: evidence from cell lines down-regulated for OPN expression by a targeted ribozyme. Clin. Exp. Metastasis 13: 453-462.
12. Franzen, A., and Heinegard, D. 1985. Isolation and characterization of two sialoproteins present only in bone calcified matrix. Biochem. J. 232: 715-724.
13. Gigchelli, C.M., Bae, N., Almeida, M., Denhardt, D.T., Alpers, C.E., and Schwartz, S.M. 1993. Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. J. Clin. Invest. 92: 1686-1696.
14. Gunthert, U., Hofmann, M., Rudy, W., Reber, S., Zoller, M., Haussmann, I., Matzku, S., Wenzel, A., Ponta, H., and Herrlich, P. 1991. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell 65: 13-24.
15. Helfrich, M.H., Nesbitt, S.A., Dorey, E.L., and Horton, M.A. 1994. Rat osteoclasts adhere to a wide range of RGD (Arg-Gly-Asp) peptide-containing proteins, including the bone sialoproteins and fibronectin, via a beta 3 integrin. J. Bone Miner. Res. 7: 335-343.
16. Hirota, S., Imakita, M., Khori, K., Ito, A., Morii, E., Adachi, S., Kim, H.-M., Kitamura, Y., Yutani, C., and Momura, S. 1993. Expression of osteopontin mRNA by macrophages in atherosclerotic plaques. A possible association with calcification. Am. J. Pathol. 143: 1003-1008.
17. Hu, D.D., Lin, E.C.K., Kovach, N.L., Hoyer, J.R., and Smith, J.W. 1995. A biochemical characterization of the binding of osteopontin to integrin αvβ3, αvβ1 and αvβ5. J. Biol. Chem. 270: 26232-26238.
18. Hwang, S.-M., Lopez, C.A., Heck, D.E., Gardner, C.R., Laskin, D.L., Laskin, J. D., and Denhardt, D.T. 1994. Osteopontin inhibits induction of nitric oxide synthase gene expression by inflammatory mediators in mouse kidney epithelial cells. J. Biol. Chem. 269: 711-715.
19. Iizuka, J., and Uede, T. Unpublished observation.
20. Ikeda, T., Shirasawa, T., Esaki, Y., Yoshiki, S., and Hirokawa, K. 1993. Osteopontin mRNA is expressed by smooth muscle-derived foam cells in human atherosclerotic lesions of the aorta. J. Clin. Invest. 92: 2814-2820.
21. Isobe, K.I., and Nakashima, I. 1993. Abundant production of nitric oxide from murine macrophages by direct stimulation of tumor cells. Biochem. Biophys. Res. Commun. 192: 499-504.
22. Katagiri, Y., Mori, K., Hara, T., Tanaka, K., Murakami, M., and Uede, T. 1995. Functional analysis of the osteopontin molecule. Ann. N.Y. Acad. Sci. 760: 371-374.
23. Katagiri, Y., Murakami, M., Mori, K., Iizuka, J., Hara, T., Tanaka, K., Jia, W.-Y., Chambers, A.F., and Uede, T. 1996. Non-RGD domains of osteopontin promote cell adhesion without involving αv integrins. J. Cell. Biochem. 62: 123-131.
24. Kohri, K., Nomura, S., Kitamura, Y., Nagata, T., Yoshioka, K., Iguchi, M., Yamate, T., Umekawa, T., Suzuki, Y., Sinohara, H., and Kurita, T. 1993. Structure and expression of the mRNA coding urinary stone protein (osteopontin). J. Biol. Chem. 268: 15180-15184.
25. Lampe, M.A., Patarca, R., Iregui, M.V., and Cantor, H. 1991. Polyclonal B cell activation by the Eta-1 cytokine and the development of systemic autoimmune disease. J. Immunol. 147: 2902-2906.
26. Liaw, L., Almeida, M., Hart, C.E., Schwartz, S.M., and Giachelli, C.M. 1994. Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro. Circ. Res. 74: 214-224.
27. Liaw, L., Lindner, V., Schwartz, S.M., Chambers, A.F., and Giachelli, C.M. 1995. Osteopontin and β3 integrin are coordinately expressed in regenerating endothelium in vivo and stimulate Arg-Gly-Asp-dependent endothelial migration in vitro. Circ. Res. 77: 665-672.
28. Liaw, L., Skinner, M.P., Ranies, E.W., Ross, R., Cheresh, D.A., Schwartz, S.M., and Giachelli, C.M. 1995. The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins: role of αvβ3 in smooth muscle migration to osteopontin in vitro. J. Clin. Invest. 95: 713-724.
29. Miyauchi, A., Alvarez, J., Greenfield, E.M., Teti, A., Grano, M., Colucci, S., Zambonin-Zallone, A., Ross, F.P., Teitelbaum, S.L., Cheresh, D., and Hruska, K.A. 1991. Recognition of osteopontin and related peptides by an αvβ3 integrin stimulates immediate cell signals in osteoclasts. J. Biol. Chem. 266: 20369-20374.
30. Mongini, P.K., Paul, W.E., and Metcaf, E.S. 1982. T cell regulation of immunoglobulin class expression in the antibody response to trinitrophenyl-ficoll. Evidence for T cell enhancement of the immunoglobulin class switch. J. Exp. Med. 155: 884-982.
31. Mori, K. 1994. Studies on expression and function of Eta-1 (early T lymphocyte activation-1) in autoimmune prone MRL/Mp-lpr/lpr mice. Hokkaido J. Med. Sci. 69: 708-717.
32. Mori, K., Kobayashi, S., Inobe, M., Jia, W.-J., Tamakoshi, M., Miyazaki, T., and Uede, T. 1994. In vivo cytokine expression in various T cell subsets of the autoimmune MRL-Mp-lpr/lpr mouse. Autoimmunity 17: 49-57.
33. O'Brien, K.D., Kuusisto, J., Reichenbach, D.D., Ferguson, M., Giachelli, C., Alpers, C.E., and Otto, C.M. 1995. Osteopontin is expressed in human valvular lesions. Circulation 92: 2163-2168.
34. Oldberg, A., Franzen, A., and Heinegard, D. 1980. Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell binding sequence. Proc. Natl. Acad. Sci. U.S.A. 83: 8819-8823.
35. Padanilam, B.J., Martin, D.R., and Hammerman, M.C. 1996. Insulin-like growth factor I-enhanced renal expression of osteopontin after acute ischemic injury in rats. Endocrinology 137: 2133-2140.
36. Oates, A.J., Barraclough, R., and Rudland, P.S. 1996. The identification of osteopontin as a metastasis-related gene product in a rodent mammary tumour model. Oncogene 13: 97-104.
37. Patarca, R., Freeman, G.J., Singh, R.P., Wei, F.-Y., Dufee, T., Blattner, F., Regnier, D.C., Kozak, C.A., Mock, B.A., Morse, III, H.C., Jerrells, T.R., and Cantor, H. 1989. Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection. J. Exp. Med. 170: 145-161.
38. Patarca, R., Saavedra, R.A., and Cantor, H. 1993. Molecular and cellular basis of genetic resistance to bacterial infection: the role of the early T-lymphocyte activation-1/osteopontin gene. Crit. Rev. Immunol. 13: 225-246.
39. - lymphocytes during the development of murine autoimmune disease. J. Exp. Med. 172: 1177-1183.
40. Pinsky, D.J., Cai, B., Yang, X., Rodriguez, C., Sciacca, R.R., and Cannon, P.J. 1995. The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor beta. J. Clin. Invest. 95: 677-685.
41. Prince, C.W. 1989. Secondary structure predictions for rat osteopontin. Connect. Tissue Res. 21: 15-20.
42. Reinholt, F.P., Hultenby, K., Oldber, A., and Heinegard, D. 1990. Osteopontin: a possible anchor of osteoclasts to bone. Proc. Natl. Acad. Sci. U.S.A. 87: 4473-4475.
43. Robev, P.-G., Bianco, P., and Termine, J.D. 1992. The cellular biology and molecular biochemistry of bone formation, p. 241-263. In Core, F.L., and Marus, M.J. (eds), Disorders of mineral metabolism, Raven Press, New York.
44. Senger, D.R., Perruzzi, C.A., Cracey, C.F., Papadopoulos, A., and Tenen, D.G. 1988. Secreted phosphoproteins associated with neoplastic transformation, close homology with plasma proteins cleaved during blood coagulation. Cancer Res. 48: 5770-5774.
45. Senger, D.R., Perruzzi, C.A., Papadopoulos, A., and Tenen, D.G. 1989. Purification of a human milk protein closely similar to tumor-secreted phosphoproteins and osteopontin. Biochim. Biophys. Acta 996: 43-48.
46. Senger, D.R., Perruzzi, C.A., Papadopoulos-Sergiou, A., and Van De Water, L. 1994. Adhesive properties of osteopontin: regulation by a naturally occurring thrombin-cleavage in close proximity to the GRGDS cell-binding domain. Mol. Biol. Cell 5: 565-574.
47. Singh, K., Balligand, J.-L., Fischer, T.A., Smith, T.W., and Kelly, R.A. 1995. Glucocorticoids increase osteopontin expression in cardiac myocytes and microvascular endothelial cells. J. Biol. Chem. 270: 28471-28478.
48. Singh, R.P., Patarca, R., Schwartz, J., Singh, P., and Cantor, H. 1990. Definition of a specific interaction between the early T lymphocyte activation 1 (Eta-1) protein and murine macrophages in vitro and its effect upon macrophages in vivo. J. Exp. Med. 171: 1931-1942.
49. Shiraga, H., Min, W., VanDusen, W.J., Clayman, M.D., Miner, D., Terrell, C.H., Sherbotie, J.R., Foreman, J.W., Przysiecki, C., Neilson, E.G., and Hoyer, J.R. 1992. Inhibition of calcium oxalate crystal growth in vitro by uropontin: another member of the aspartic acid-rich protein super-family. Proc. Natl. Acad. Sci. U.S.A. 89: 426-430.
50. Slack, J.H., Hang, L., Barkely, J., Falton, R.J., D'Hoostlelaere, L., Robinson, A., and Dixon, F.J. 1984. Isotypes of spontaneous and mitogen-induced autoantibodies in SLE-prone mice. J. Immunol. 132: 1271-1275.
51. Sleemann, J.P., Arming, S., Moll, J.F., Hekele, A., Rudy, W., Sherman, L.S., Kreil, G., Ponta, H., and Herrlich, P. 1996. Hyaluronate-independent metastatic behavior of CD44 variant-expressing pancreatic carcinoma cells. Cancer Res. 56: 3134-3141.
52. Smith, L.L., Cheung, H.-K., Ling, L.E., Chen, J., Sheppard, D., Pytela, R., and Giachelli, C.M. 1996. Osteopontin N-terminal domain contains a cryptic adhesive sequence recognized by α9β1 integrin. J. Biol. Chem. 271: 28485-28491.
53. Sodek, J., Chen, J., Kasugai, S., Nagata, T., Zhang, Q., McKee, M.D., and Nanci, A. 1992. Elucidating the functions of bone sialoprotein and osteopontin in bone formation, p. 297-306. In Slavkin, H., and Price, P. (eds), Chemistry and biology of mineralized tissues, Elsevier, New York.
54. Ungureanu-Longrois, D., Balligand, J.L., Kelly, R.A., and Smith, T.W. 1995. Myocardial contractile dysfunction in the systemic inflammatory response syndrome: role of a cytokine-inducible nitric oxide synthase in cardiac myocytes. J. Mol. Cell. Cardiol. 271: 155-167.
55. Van Dijk, S., D'Errico, J.A., Somerman, M.J., Farach-Carson, M.C., and Butler, W.T. 1993. Evidence that a non-RGD domain in rat osteopontin is involved in cell attachment. J. Bone Mineral Res. 12: 1499-1505.
56. Weber, G.F., Ashkar, S., Glimcher, M.J., and Cantor, H. 1996. Receptor-ligand interaction between CD44 and osteopontin (Eta-1). Science 271: 509-512.
57. Weinreb, M., Shinar, D., and Rodan, G.A. 1990. Different pattern of alkaline phosphatase, osteopontin, and osteocalcine expression in developing bone visualized by in situ hybridization. J. Bone Mineral Res. 5: 831-842.
58. Williams, E.B., Halpert, I., Wickline, S., Davison, G., Parks, W.C., and Rottman, J.N. 1995. Osteopontin expression is increased in the heritable cardiomyopathy of syrian hamsters. Circulation 92: 705-709.
59. Xuan, J.W., Hota, C., and Chambers, A.F. 1994. Recombinant GST-human osteopontin fusion protein is functional in RGD-dependent cell adhesion. J. Cell. Biochem. 54: 247-255.
60. Yamada, K.M. 1991. Adhesive recognition sequences. J. Biol. Chem. 266: 12809-12812.
61. Yue, T.-L., Mckenna, P.J., Ohlstein, E.H., Farach-Carson, M.C., Butler, W.T., Johanson, K., McDevitt, P., Feuerstein, G.Z., and Stadel, J. 1994. Osteopontin-stimulated vascular smooth muscle migration is mediated by β3 integrin. Exp. Cell Res. 214: 459-464.