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Volumn 14, Issue 6, 1997, Pages 786-792

Role of brain tissue localized purine metabolizing enzymes in the central nervous system delivery of anti-HIV agents 2'-β-fluoro-2',3'-dideoxyinosine and 2'-β-fluoro-2',3'-dideoxyadenosine in rats

(3) Singhal, Dharmendra a Morgan, Michael E a Andersen, Bradley D a

a UNIVERSITY OF UTAH (United States)

Author keywords

Adenosine deaminase; Blood brain barrier; Dideoxyadenosine; Inhibitor; Purine nucleoside phosphorylase

Indexed keywords

2',3' DIDEOXY 2' FLUOROADENOSINE; 2',3' DIDEOXY 2' FLUOROINOSINE; 2',3' DIDEOXYADENOSINE; ADENOSINE DEAMINASE; DIDANOSINE; PENTOSTATIN; PURINE NUCLEOSIDE PHOSPHORYLASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN TISSUE; CONTROLLED STUDY; DRUG BRAIN LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG DISTRIBUTION; DRUG PENETRATION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENOSINE DEAMINASE; ANIMALS; ANTI-HIV AGENTS; BRAIN; BRAIN CHEMISTRY; DIDANOSINE; DIDEOXYADENOSINE; ENZYME INHIBITORS; INFUSIONS, INTRAVENOUS; MALE; PENTOSTATIN; PURINE-NUCLEOSIDE PHOSPHORYLASE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030929865 PISSN: 07248741 EISSN: None Source Type: Journal
DOI: 10.1023/A:1012110724604 Document Type: Article

Times cited : (27)

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