Metabolism of isomeric nitrobenzo[a]pyrenes leading to DNA adducts and mutagenesis

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 376, Issue 1-2, 1997, Pages 43-51

  Fu, Peter P ^a   Qui, Feng Yun ^b   Jung, Hyewook ^a   Von Tungeln, Linda S ^a   Zhan, De Jin ^c   Lee, Mei Jing ^d   Wu, Yu Sen ^e   Heflich, Robert H ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^c GUANGZHOU MEDICAL UNIVERSITY   (China)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^e Hungkung Jr Coll Nursing Med T   (Taiwan)

Author keywords

Chinese hamster ovary cell; DNA adduct; hprt; Metabolism; Mutation; Nitro polycyclic aromatic hydrocarbon; Nitrobenzo a pyrene; Nitroreduction; Ring oxidation; Salmonella typhimurium

Indexed keywords

AROMATIC NITRO COMPOUND; BENZO[A]PYRENE DERIVATIVE;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; FEMALE; MUTAGENESIS; MUTAGENICITY; MUTATION; NONHUMAN; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; STRUCTURE ACTIVITY RELATION; XENOBIOTIC METABOLISM;

ANIMALS; BENZOPYRENES; CHEMISTRY, PHYSICAL; DNA ADDUCTS; ISOMERISM; MICROSOMES, LIVER; MUTAGENICITY TESTS; MUTAGENS; NITRATES; POLYCYCLIC COMPOUNDS; RATS; SALMONELLA TYPHIMURIUM; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0030926118     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(97)00024-9     Document Type: Article

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