Molecular characterization of mutation and comparison of mutation profiles in the hprt gene of Chinese hamster ovary cells treated with benzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, 1-nitrobenzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, and 3-Nitrobenzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide

Environmental and Molecular Mutagenesis

Volumn 27, Issue 1, 1996, Pages 19-29

  Zhan, De Jin ^a,b   Heflich, Robert H ^a   Fu, Peter P ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

CHO cell; DNA sequencing; hprt gene; Mutation; Nitrobenzo a pyrene; RT PCR

Indexed keywords

AROMATIC NITRO COMPOUND; BENZO[A]PYRENE DERIVATIVE;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENE MUTATION; MUTAGENICITY; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANIMALS; BASE SEQUENCE; CARCINOGENS, ENVIRONMENTAL; CHO CELLS; CRICETINAE; CRICETULUS; DNA ADDUCTS; DNA DAMAGE; DNA MUTATIONAL ANALYSIS; DNA, COMPLEMENTARY; ENVIRONMENTAL POLLUTANTS; FRAMESHIFT MUTATION; GENES; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUTAGENESIS; MUTATION; POINT MUTATION; RNA, MESSENGER; SEQUENCE DELETION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029881257     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(1996)27:1<19::AID-EM3>3.0.CO;2-9     Document Type: Article

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