Cysteine residues in human lysosomal acid lipase are involved in selective cholesteryl esterase activity

Biochemical Journal

Volumn 326, Issue 1, 1997, Pages 265-269

  Pagani, Franco ^a   Pariyarath, Rajalakshmi ^a   Stuani, Cristiana ^a   Garcia, Rodolfo ^a   Baralle, Francisco E ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACID LIPASE; CHOLESTEROL ESTERASE; CHOLESTEROL OLEATE; COMPLEMENTARY DNA; CYSTEINE; LYSOSOME ENZYME; MUTANT PROTEIN; THIOL GROUP;

AMINO ACID SUBSTITUTION; ARTICLE; CLONING VECTOR; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENETIC TRANSFECTION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

HERPES; SIMPLEXVIRUS;

EID: 0030924426     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3260265     Document Type: Article

References (35)

1. Brown, M. S. and Goldstein, J. L. (1986) Science 232, 34-47
2. Assman, G. and Seedorf, U. (1995) in The Metabolic Basis of Inherited Diseases, vol. 2 (Scriver, C. R., Beaudet, A. L., Sly, W. S. and Valle, D., eds.), pp. 2563-2587, McGraw-Hill, New York
3. Coates, P. M., Langer, T. and Cortner, J. A. (1986) Atherosclerosis 62, 11-20
4. Yatsu, F. M., Hagemenas, F. C., Manaugh, L. C. and Galambos, T. (1980) Lipids 15, 1019-1022
5. Anderson, R. A. and Sando, G. N. (1991) J. Biol. Chem. 266, 22479-22484
6. Hide, W. A., Chan, L. and Li, W. H. (1992) J. Lipid Res. 33, 167-178
7. Sando, G. N. and Henke, V. L. (1982) J. Lipid Res. 23, 114-123
8. Pariyarath, R., Pagani, F., Stuani, C., Garcia, R. and Baralle, F. E. (1996) FEBS Lett. 397, 79-82
9. Nakagawa, H., Matsubara, S., Kuriyama, M., Yoshidome, H., Fujiyama, J., Yoshida, H. and Osame, M. (1995) J. Lipid Res. 36, 2212-2218
10. Langin, D., Laurell, H., Holst, L. S., Belfrage, P. and Holm, C. (1993) Proc. Natl. Acad. Sci. USA 90, 4897-4901
11. Brzozowski, A. M., Derewenda, U., Derewenda, Z. S., Dodson, G. G., Lawson, D. M., Turkenburg, J. P., Bjorkling, F., Huge-Jensen, B., Patkar, S. A. and Thim, L. (1991) Nature (London) 351, 491-494
12. Brady, L., Brzozowski, A. M., Derewenda, Z. S., Dodson, E., Dodson, G., Tolley, S., Turkenburg, J. P., Christiansen, L., Huge-Jensen, B., Norskov, L. et al. (1990) Nature (London) 343, 767-770
13. Winkler, F. K., D'Arcy, A. and Hunziker, W. (1990) Nature (London) 343, 771-774
14. Schrag, J. D., Li, Y., Wu, S. and Cygler, M. (1991) Nature (London) 351, 761-764
15. Lowe, M. E. (1992) J. Biol. Chem. 267, 17069-17073
16. Beer, H. D., Wohlfahrt, G., McCarthy, J. E. G., Schomburg, D. and Schmid, R. D. (1996) Protein Eng. 9, 507-517
17. Sando, G. N. and Rosenbaum, L. M. (1985) J. Biol. Chem. 260, 15186-15193
18. Rindler-Ludwig, R., Patsch, W., Sailer, S. and Braunsteiner, H. (1977) Biochim. Biophys. Acta 488, 294-304
19. Burton, B. K. and Mueller, H. W. (1980) Biochim. Biophys. Acta 618, 449-460
20. Sheriff, S., Du, H. and Grabowski, G. A. (1995) J. Biol. Chem. 270, 27766-27772
21. Gargouri, Y., Moreau, H., Pieroni, G. and Verger, R. (1988) J. Biol. Chem. 263, 2159-2162
22. Gargouri, Y., Moreau, H., Pieroni, G. and Verger, R. (1989) Eur. J. Biochem. 180, 367-371
23. Timmermans, M. Y. J., Reekmans, G. and Kupers, L. P. M. (1996) Biochem. J. 314, 931-936
24. Fuerst, T. R., Earl, P. L. and Moss, B. (1987) Mol. Cell. Biol. 7, 2538-2544
25. Pagani, F., Garcia, R., Pariyarath, R., Stuani, C., Gridelli, B., Paone, G. and Baralle, F. E. (1996) Hum. Mol. Genet. 10, 1611-1617
26. Higuchi, R., Krummel, B. and Saiki, R. K. (1988) Nucleic Acids Res. 16, 7351-7367
27. Pittman, R. C., Khoo, J. C. and Steinberg, D. (1975) J. Biol. Chem. 250, 4505-4511
28. Ameis, D., Merkel, M., Eckerskorn, C. and Greten, H. (1994) Eur. J. Biochem. 219, 905-914
29. Creighton, T. E. (1990) Protein Structure: A Practical Approach, pp. 155-167, IRL Press, Oxford
30. Sambrook, J., Fritsch, E. F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd edn., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
31. Dugi, K. A., Dichek, H. L., Talley, G. D., Brewer, B. H. and Santamaria-Fojo, S. (1992) J. Biol. Chem. 267, 25086-25091
32. Dugi, K. A., Dichek, H. L. and Santamaria-Fojo, S. (1995) J. Biol. Chem. 270, 25396-25401
33. Kobayashi, J., Applebaum-Bowden, D., Dugi, K. A., Brown, D. R., Kashyap, V. S., Parrott, C., Duarte, C., Maeda, N. and Santamarina-Fojo, S. (1996) J. Biol. Chem. 271, 26296-26301
34. Pawlowski, J. E. and Penning, T. M. (1994) J. Biol. Chem. 269, 13502-13510
35. Chen, D. and Stallcup, M. R. (1994) J. Biol. Chem. 269, 7914-7918