Characterization of DNA binding sites for the BvgA protein of Bordetella pertussis

Journal of Bacteriology

Volumn 179, Issue 11, 1997, Pages 3790-3792

  Karimova, Gouzel ^a   Ullmann, Agnes ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; DNA;

ARTICLE; BACTERIAL VIRULENCE; BORDETELLA PERTUSSIS; GENE EXPRESSION; GENE STRUCTURE; NONHUMAN; PLEIOTROPY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; REGULATOR GENE;

BACTERIA (MICROORGANISMS); BORDETELLA PERTUSSIS;

EID: 0030921947     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.179.11.3790-3792.1997     Document Type: Article

References (21)

1. Aricò, B., J. F. Miller, C. Roy, S. Stibitz, D. Monack, S. Falkow, R. Gross, and R. Rappuoli. 1989. Sequences required for expression of Bordetella pertussis virulence factors share homology with prokaryotic signal transducing proteins. Proc. Natl. Acad. Sci. USA 86:6671-6675.
2. Beier, D., B. Schwarz, T. M. Fuchs, and R. Gross. 1995. In vivo characterization of the unorthodox BvgS two-component sensor protein of Bordetella pertussis. J. Mol. Biol. 248:596-610.
3. Boucher, P. E., and S. Stibitz. 1995. Synergetic binding of RNA polymerase and BvgA phosphate to the pertussis toxin promoter of Bordetella pertussis. J. Bacteriol. 177:6486-6491.
4. Boucher, P. E., F. D. Menozzi, and C. Locht. 1994. The modular architecture of bacterial response regulators. Insight into the activation mechanism of the BvgA transactivator of Bordetella pertussis. J. Mol. Biol. 241:363-377.
5. Gross, R., and R. Rappuoli. 1988. Positive regulation of pertussis toxin expression. Proc. Natl. Acad. Sci. USA 85:3913-3917.
6. Ho, S., H. D. Hunt, R. M. Horton, J. K. Pullen, and L. Pease. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59.
7. Karimova, G., J. Bellalou, and A. Ullmann. 1996. Phosphorylation-dependent binding of BvgA to the upstream region of the cyaA gene of Bordetella pertussis. Mol. Microbiol. 20:489-496.
8. Knapp, S., and J. J. Mekalanos. 1988. Two trans-acting regulatory genes (vir and mod) control antigenic modulation in Bordetella pertussis. J. Bacteriol. 170:5059-5066.
9. Laoide, B. M., and A. Ullmann. 1990. Virulence dependent and independent regulation of the Bordetella pertussis cya operon. EMBO J. 9:999-1005.
10. Miller, J. F., J. J. Mekalanos, and S. Falkow. 1989. Coordinate regulation and sensory transduction in the control of bacterial virulence. Science 243: 916-922.
11. Roy, C. R., and S. Falkow. 1991. Identification of Bordetella pertussis regulatory sequences required for transcriptional activation of the fhaB gene and autoregulation of the bvgAS operon. J. Bacteriol. 173:2385-2392.
12. Roy, C. R., J. F. Miller, and S. Falkow. 1989. The bvgA gene of Bordetella pertussis encodes a transcriptional activator required for coordinate regulation of several virulence genes. J. Bacteriol. 171:6338-6344.
13. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
14. Scarlato, V., B. Aricò, A. Prugnola, and R. Rappuoli. 1991. Sequential activation and environmental regulation of virulence genes in Bordetella pertussis. EMBO J. 10:3971-3975.
15. Scarlato, V., A. Prugnola, B. Aricò, and R. Rappuoli. 1990. Positive transcriptional feedback at the bvg locus controls expression of virulence factors in Bordetella pertussis. Proc. Natl. Acad. Sci. USA 87:6753-6757.
16. Schleif, R. 1996. Two positively regulated systems, ara and mal, p. 1302. In F. C. Neidhardt et al. (ed.), Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed. AMS Press, Washington, D.C.
17. Steffen, P., S. Goyard, and A. Ullmann. 1995. Phosphorylated BvgA is sufficient for transcriptional activation of virulence-regulated genes in Bordetella pertussis. EMBO J. 15:102-109.
18. Steffen, P., S. Goyard, and A. Ullmann. 1997. The Bordetella pertussis sigma subunit of RNA polymerase confers enhanced expression of fha in Escherichia coli. Mol. Microbiol. 23:945-954.
19. Stibitz, S., A. A. Weiss, and S. Falkow. 1988. Genetic analysis of a region of the Bordetella pertussis chromosome encoding filamentous hemagglutinin and the pleiotropic regulatory locus vir. J. Bacteriol. 170:2904-2913.
20. Stibitz, S., and M.-S. Yang. 1991. Subcellular localization and immunological detection of proteins encoded by the vir locus of Bordetella pertussis. J. Bacteriol. 173:4288-4296.
21. Zu, T., R. Manetti, R. Rappuoli, and V. Scarlato. 1996. Differential binding of BvgA to two classes of virulence genes of Bordetella pertussis direct promoter selectivity by RNA polymerase. Mol. Microbiol. 21:557-565.