A structure-based approach to drug discovery; crystallography and implications for the development of antiparasite drugs

Parasitology

Volumn 114, Issue SUPPL. 1, 1997, Pages

  Hunter, W N ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Crystallography; Drug discovery; Enzyme structure; Parasitology; Trypanothione reductase

Indexed keywords

ANTIPARASITIC AGENT; GLUTATHIONE; GLUTATHIONE DISULFIDE; TRYPANOTHIONE; TRYPANOTHIONE DISULFIDE; TRYPANOTHIONE REDUCTASE; UNCLASSIFIED DRUG;

CONFERENCE PAPER; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DERIVATIZATION; DRUG DESIGN; DRUG STRUCTURE; ENZYME ANALYSIS; ENZYME STRUCTURE; PARASITOLOGY; PRIORITY JOURNAL; RECOMBINANT DNA TECHNOLOGY; X RAY DIFFRACTION;

ANTIPARASITIC AGENTS; COMPUTATIONAL BIOLOGY; COMPUTER GRAPHICS; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; DRUG INDUSTRY; HELMINTH PROTEINS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NADH, NADPH OXIDOREDUCTASES; PROTOZOAN PROTEINS;

EID: 0030921823     PISSN: 00311820     EISSN: None     Source Type: Journal    
DOI: 10.1017/s0031182097008962     Document Type: Article

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