Intestinal absorption barriers and transport mechanisms, including secretory transport, for a cyclic peptide, fibrinogen antagonist

Pharmaceutical Research

Volumn 13, Issue 1, 1996, Pages 114-119

  Aungst, Bruce J ^a   Saitoh, Hiroshi ^b  

^a DUPONT COMPANY   (United States)

^b HOKKAIDO UNIVERSITY HOSPITAL   (Japan)

Author keywords

Absorption; DMP 728; Fibrinogen antagonist; GPIIb IIIa antagonist; Intestinal transport; P glycoprotein

Indexed keywords

CYCLO(DEXTRO 2 AMINOBUTYRYL 2 N METHYLARGINYLGLYCYLASPARTYL 3 AMINOMETHYLBENZOIC ACID) METHANESULFONATE; GLYCOPROTEIN P; VERAPAMIL;

ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; DIFFUSION; DRUG METABOLISM; DRUG TRANSPORT; INTESTINE ABSORPTION; LIPOPHILICITY; MALE; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; RAT; TISSUE HOMOGENATE;

ANIMALS; ANTIBODIES, MONOCLONAL; BIOLOGICAL TRANSPORT; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FIBRINOGEN; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; MALE; MESYLATES; P-GLYCOPROTEIN; PEPTIDES, CYCLIC; PLATELET AGGREGATION INHIBITORS; PROTONS; RATS; RATS, SPRAGUE-DAWLEY; VERAPAMIL;

EID: 0029866361     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016093704095     Document Type: Article

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