Adenovirus infection enhances killing of melanoma cells by a mitotoxin

Cancer Research

Volumn 57, Issue 10, 1997, Pages 1873-1876

  Satyamoorthy, Kapaettu ^a   Soballe, Peter W ^a   Soans, Francis ^a   Herlyn, Meenhard ^a  

^a WISTAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC AGENT; PLANT TOXIN; PROTEIN SYNTHESIS INHIBITOR; RECOMBINANT BASIC FIBROBLAST GROWTH FACTOR; SAPORIN;

ADENOVIRUS; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL GROWTH; CONTROLLED STUDY; CYTOTOXICITY; INTERNALIZATION; MELANOMA; NONHUMAN; PRIORITY JOURNAL; TUMOR CELL; VIRUS INFECTION; VIRUS REPLICATION;

ADENOVIRIDAE; ADENOVIRIDAE INFECTIONS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; DRUG SYNERGISM; FIBROBLAST GROWTH FACTOR 2; HUMANS; IMMUNOTOXINS; MELANOMA; MICE; N-GLYCOSYL HYDROLASES; NEOPLASM TRANSPLANTATION; PLANT PROTEINS;

EID: 0030912507     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Nilsson, L., Asanto, K., Svensson, B., Poulsen, F. M., and Nygard, O. Reduced turnover of the elongation factor EF-1-ribosome complex after treatment with the protein synthesis inhibitor II from barley seeds. Biochim. Biophys. Acta, 868: 62-70, 1986.
2. Lappi, D. A., Ying, W., Barthelemy, I., Martineau, D., Prieto, I., Benatti, L., Soria, M., and Baird, A. Expression and activities of a recombinant basic fibroblast growth factor-saporin fusion protein. J. Biol. Chem., 269: 12552-12558, 1994.
3. Beitz, J. G., Davol, P., Clark, J. W., Kato, J., Medina, M., Frackelton, A. R., Lappi, D. A., Baird, A., and Calabresi, P. Antitumor activity of basic fibroblast growth factor saporin mitotoxin in vitro and in vivo. Cancer Res., 52: 227-230, 1992.
4. Davol, P., and Frackelton, A. R. The mitotoxin basic fibroblast growth factor-saporin effectively targets human prostatic carcinoma in an animal model. J. Urol., 156: 1174-1170, 1996.
5. Becker, D., Lee, P. L., Rodeck, U., and Herlyn, M. Inhibition of the fibroblast growth factor receptor 1 (FGFR-1) gene in human melanocytes and malignant melanomas leads to inhibition of proliferation and signs indicative of differentiation. Oncogene, 7: 2303-2313, 1992.
6. Wang, Y., Rao, U., Mascari, R., Richards, T. J., Panson, A. J., Edington, H. D., Shipe-Spotlos, J. M., Donnelly, S. S., Kirkwood, J. M., and Becker, D. Molecular analysis of melanoma precursor lesions. Cell Growth & Differ., 7: 1733-1740, 1996.
7. Sorkin, A., and Waters, C. M. Endocytosis of growth factor receptors. BioEssays, 15: 375-382, 1993.
8. Berg, T., Gjoen, T., and Bakke, O. Physiological functions of endosomal proteolysis. Biochem. J., 307: 313-326, 1995.
9. Davol, P., Beitz, J. G., and Frackelton, A. R., Jr. Autocrine down-regulation of basic fibroblast growth factor receptors causes mitotoxin resistance in a human melanoma cell line. J. Invest. Dermatol., 104: 916-921, 1995.
10. Seth, P. Mechanism of adenovirus-mediated endosome lysis: role of the intact adenovirus capsid structure. Biochem. Biophys. Res. Commun., 205: 1318-1324, 1994.
11. Carrasco, L. Entry of animal viruses and macromolecules into cells. FEBS Lett., 350: 151-154, 1994.
12. Graham, F. L., and Prevec, L. Manipulation of adenovirus vectors. In: E. J. Murrey (ed.), Methods in Molecular Biology, Vol. 7, pp. 109-128. Clifton, NJ: The Humana Press, Inc., 1991.
13. Herlyn, M., Thurin, J., Balaban, G., Bennicelli, J. L., Herlyn, D., Elder, D. E., Bondi, E., Guerry, D., IV, Nowell, P. C., Clark, W. H., Jr., and Koprowski, H. Characteristics of cultured human melanocytes isolated from different stages of tumor progression. Cancer Res., 45: 5670-5676, 1985.
14. Schmid, I., Uittenbogaart, C., and Giogi, J. Sensitive method for measuring apoptosis and cell surface phenotype in human thymocytes by flow cytometry, Cytometry, 15: 12-16, 1994.
15. Gorczyca, W., Bigman, K., Mittleman, A., Ahmed, T., Gong, J., Melamed, M., and Darzynkiewicz, Z. Induction of DNA strand breaks associated with apoptosis during treatment of leukemias. Leukemia (Baltimore), 7: 659-664, 1993.
16. Davol, P., Beitz, J. G., Mohler, M., Ying, W., Cook, J., Lappi, D. A., and Frackelton, A. R., Jr. Saporin toxins directed to basic fibroblast growth factor receptors effectively target human ovarian teratocarcinoma in an animal model. Cancer (Phila.), 76: 79-85, 1995.
17. Kochi, S. K., and Collier, R. J. DNA fragmentation and cytolysis in U937 cells treated with diphtheria toxin and other inhibitors of protein synthesis. Exp. Cell Res., 208: 296-302, 1993.
18. FitzGerald, D. J. P., Padmanabhan, R., Pastan, I., and Willingham, M. C. Adenovirus-induced release of epidermal growth factor and Pseudomonas toxin into cytosol of KB cells during receptor-mediated endocytosis. Cell, 32: 607-617, 1983.
19. Huang, S., Endo, R. I., and Nemerow, G. R. Upregulation of integrins ανβ3 and ανβ5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery. J. Virol., 69: 2257-2263, 1995.
20. Greber, U. F., Singh, I., and Helenius, A. Mechanisms of virus uncoating. Trends Microbiol., 2: 52-56, 1994.