EGF receptor activation stimulates endogenous gastrin gene expression in canine G cells and human gastric cell cultures

Journal of Clinical Investigation

Volumn 99, Issue 11, 1997, Pages 2762-2771

  Ford, Michael G ^a   Del Valle, John ^a   Soroka, Carol J ^c   Merchant, Juanita L ^a,b,d  

^a UNIVERSITY OF MICHIGAN   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MSRB I   (United States)

Author keywords

DNA element; Gene expression; Gere; Sp1; TGF

Indexed keywords

BOMBESIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GASTRIN; NEUROPEPTIDE; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; GASTRIN CELL; GASTRIN RELEASE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL;

EID: 0030911587     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119466     Document Type: Article

References (49)

1. Giraud, A.S., A.H. Soll, F. Cuttitta, and J.H. Walsh. 1987. Bombesin stimulation of gastrin release from canine gastrin cells in primary culture. Am. J. Physiol. 252:G413-G420.
2. DelValle, J., and T. Yamada. 1990. Amino acids and amines stimulate gastrin release from canine antral G-cells via different pathways. J. Clin. Invest. 85:139-143.
3. Sugano, K., J. Park, A.H. Soll, and T. Yamada. 1987. Stimulation of gastrin release by bombesin and canine gastrin-releasing peptides. J. Clin. Invest. 79:935-942.
4. Campos, R.V., A.M.J. Buchan, R.M. Meloche, R.A. Pederson, Y.N. Kwok, and D.H. Coy. 1990. Gastrin secretion from human antral G cells in culture. Gastroenterology. 99:36-44.
5. Brand, S.J., and D. Stone. 1988. Reciprocal regulation of antral gastrin and somatostatin gene expression by omeprazole-induced achlorhydria. J. Clin. Invest. 82:1059-1066.
6. Wu, S.V., A. Giraud, M. Mogard, K. Sumii, and J.H. Walsh. 1990. Effects of inhibition of gastric secretion on antral gastrin and somatostatin gene expression in rats. Am. J. Physiol. 258:G788-G793.
7. Vinter-Jensen, L., C. Orloff, J.F. Rehfeld, P.S. Seier, E.Z. Dajani, and E. Nexo. 1995. Chronic systemic treatment with epidermal growth factor induces hypergastrinaemia in Goettingen minipigs. Scand. J. Gastroenterol. 30:422-427.
8. Goodlad, R.A., M.A. Ghatei, J. Domin, S.R. Bloom, H. Gregory, and N.A. Wright. 1989. Plasma enteroglucagon, peptide YY and gastrin in rats deprived of luminal nutrition, and after urogastrone-EGF administration. A proliferative role for PYY in the intestinal epithelium? Experientia (Basel). 45:168-169.
9. Shing, Y., G. Christofori, D. Hanahan, Y. Ono, R. Sasada, K. Igarashi, and J. Folkman. 1993. Betacellulin: a mitogen from pancreatic beta cell tumors. Science (Wash. DC). 259:1604-1606.
10. Fisher, D.A., and J. Lakshmanan. 1990. Metabolism and effects of epidermal growth factor and related growth factors in mammals. Endocr. Rev. 11: 1-25.
11. Beauchamp, R.D., J.A. Barnard, C.M. McCutchen, J.A. Cherner, and R.J. Coffey, Jr. 1989. Localization of transforming growth factor α and its receptor in gastric mucosal cells. J. Clin. Invest. 84:1017-1023.
12. Murayama, Y., J.-I. Miyagawa, S. Higashiyama, S. Kondo, M. Yabu, K. Isozaki, Y. Kayanoki, S. Kanayama, Y. Shinomura, N. Taniguchi, and Y. Matsuzawa. 1995. Localization of heparin-binding epidermal growth factor-like growth factor in human gastric mucosa. Gastroenterology. 109:1051-1059.
13. Dempsey, P.J., J.R. Goldenring, C.J. Soroka, I.M. Modlin, R.W. McClure, C.D. Lind, D.A. Ahlquist, M.R. Pittelkow, D.C. Lee, E.P. Sandgren, et al. 1992. Possible role of transforming growth factor alpha in the pathogenesis of Ménétrier's disease: supportive evidence from humans and transgenic mice. Gastroenterology. 103:1950-1963.
14. Heitz, P.U., M. Kasper, S. VanNoorden, J.M. Polak, H. Gregory, and A.G.E. Pearse. 1978. Immunohistochemical localisation of urogastrone to human duodenal and submandibular glands. Gut. 19:408-413.
15. Wright, N.A., C. Pike, and G. Elia. 1990. Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in human gastrointestinal stem cells. Nature (Lond.). 343:82-85.
16. Wang, L., M.R. Lucey, A.M. Fras, E.J. Wilson, and J. Del Valle. 1993. Epidermal growth factor and transforming growth factor-alpha directly inhibit parietal cell function through a similar mechanism. J. Pharmacol. Exp. Ther. 265:308-313.
17. Massague, J. 1983. Epidermal growth factor-like transforming growth factor. II. Interaction with epidermal growth factor receptors in human placenta membranes and A431 cells. J. Biol. Chem. 258:13614-13620.
18. Kaise, M., A. Muraoka, J. Yamada, and T. Yamada. 1995. Epidermal growth factor induces H+, K+-ATPase α-subunit gene expression through an element homologous to the 3′ half-site of the c-fos serum response element. J. Biol. Chem. 270:18637-18642.
19. Godley-Merchant, J., and S.J. Brand. 1989. Regulation of the gastrin promoter by epidermal growth factor and neuropeptides. Proc. Natl. Acad. Sci. USA. 86:3036-3040.
20. Merchant, J.L., B. Demediuk, and S.J. Brand. 1991. A GC-rich element confers epidermal growth factor responsiveness to transcription from the gastrin promoter. Mol. Cell. Biol. 11:2686-2696.
21. Barranco, S.C., C.M. Townsend, Jr., C. Casartelli, B.G. Macik, N.L. Burger, W.R. Boerwinkle, and W.K. Gourley. 1983. Establishment and characterization of an in vitro model system for human adenocarcinoma of the stomach. Cancer Res. 43:1703-1709.
22. Tahara, E., H. Ito, K. Nakagami, F. Shimamoto, M. Yamamoto, and K. Sumii. 1982. Scirrhous argyrophil cell carcinoma of the stomach with multiple production of polypeptide hormones, amine, CEA, lysozyme, and HCG. Cancer. 49:1904-1915.
23. Deng, W.P., and J.A. Nickoloff. 1992. Site-directed mutagenesis of virtually any plasmid by eliminating a unique site. Anal. Biochem. 200:81-88.
24. Shiotani, A., and J.L. Merchant. 1995. cAMP regulates gastrin gene expression. Am. J. Physiol. 269:G458-G464.
25. Rosenquist, G.L., and J.H. Walsh. 1980. Radioimmunoassay of gastrin. In Gastrointestinal Hormones. G.B. Jerzy-Glass, editor. Raven Press Ltd., New York. 769-795.
26. Marshak, D.W., L.B. Aldrich, J. DelValle, and T. Yamada. 1990. Localization of immunoreactive cholecystokinin precursor to amacrine cells and bipolar cells of the macaque monkey retina. J. Neurosci. 10:3045-3055.
27. Gantz, I., T. Takeuchi, and T. Yamada. 1990. Cloning of canine gastrin cDNA's encoding variant amino acid sequences. Digestion. 46:99-104.
28. Howell, G.M., B.L. Ziober, L.E. Humphrey, J.K. Willson, L. Sun, M. Lynch, and M.G. Brattain. 1995. Regulation of autocrine gastrin expression by the TGF alpha autocrine loop. J. Cell. Physiol. 162:256-265.
29. Schreiber, E., P. Matthias, M.M. Muller, and W. Schaffner. 1989. Rapid detection of octamer binding proteins with 'mini-extracts,' prepared from a small number of cells. Nucleic Acids Res. 17:6419.
30. Zimmerman, R.P., T.S. Gates, C.G. Boehmer, and C.G. Mantyh. 1988. Epidermal growth factor receptors in the canine antrum. Peptides (Tarryt). 9: 1411-1414.
31. Koh, T.J., and T.C. Wang. 1995. Molecular cloning and sequencing of the murine gastrin gene. Biochem. Biophys. Res. Commun. 216:34-41.
32. Watson, S.A., L.G. Durrant, P.M. Wencyk, A.L. Watson, and D.L. Morris. 1991. Intracellular gastrin in human gastrointestinal tumor cells. J. Natl. Cancer Inst. 83:866-871.
33. Yoshida, K., E. Kyo, T. Tsujino, T. Sano, M. Niimoto, and E. Tahara. 1990. Expression of epidermal growth factor, transforming growth factor-alpha and their receptor genes in human gastric carcinomas; implication for autocrine growth. Jpn. J. Cancer Res. 81:43-51.
34. Merchant, J.L., G.R. Iyer, B.R. Taylor, J.R. Kitchen, E.R. Mortensen, Z. Wang, R.J. Flintoft, J. Michel, and R. Bassel-Duby. 1996. ZBP-89, a Krüppel-type zinc finger protein, inhibits EGF induction of the gastrin promoter. Mol Cell. Biol. 16:6644-6653.
35. Merchant, J.L., A. Shiotani, E. Mortensen, D. Shumaker, and D. Abraczinskas. 1995. EGF stimulation of the human gastrin promoter requires Sp1. J. Biol. Chem. 270:6314-6319.
36. Searcy, R.M., and J.-R. Malagelada. 1984. Ménétriér's disease and idiopathic hypertrophic gastropathy. Ann. Intern. Med. 100:565-570.
37. Bundgaard, J.R., T.O. Hansen, L. Friis-Hansen, I.J. Rourke, W.W. van Solinge, F.C. Nielsen, and J.F. Rehfeld. 1995. A distal Sp1-element is necessary for maximal activity of the human gastrin gene promoter. FEBS Lett. 369:225-228.
38. Polk, D.H., M.G. Ervin, J.F. Padbury, R.W. Lam, A.L. Reviczky, and D.A. Fisher. 1987. Epidermal growth factor acts as a corticotropin-releasing factor in chronically catheterized fetal lambs. J. Clin. Invest. 79:984-988.
39. Schonbrunn, A., M. Krasnoff, J.M. Westendorf, and A.H. Tashjian, Jr. 1980. Epidermal growth factor and thyrotropin-releasing hormone act similarly on a clonal pituitary cell strain. J. Cell. Biochem. 85:786-797.
40. Yajima, Y., and T. Saito. 1984. The effects of epidermal growth factor on cell proliferation and prolactin production by GH3 rat pituitary cells. J. Cell. Physiol. 120:249-256.
41. Johnson, L.K., J.D. Baxter, I. Vlodavsky, and D. Gospodarowicz. 1980. Epidermal growth factor and expression of specific genes: effects on cultured rat pituitary cells are dissociable from the mitogenic response. Proc. Natl. Acad. Sci. USA. 77:394-398.
42. Przylipiak, A., L. Kiesel, T. Rabe, K. Helm, M. Przylipiak, and B. Runnebaum. 1988. Epidermal growth factor stimulates luteinizing hormone and arachidonic acid release in rat pituitary cells. Mol. Cell. Endocrinol. 57:157-162.
43. Ikeda, H., T. Mitsuhashi, K. Kubota, N. Kuzuya, and H. Uchimura. 1984. Epidermal growth factor stimulates growth hormone secretion from superfused rat adenohypophyseal fragments. Endocrinology. 115:556-558.
44. Logsdon, C.D. 1986. Stimulation of pancreatic acinar cell growth by CCK, epidermal growth factor, and insulin in vitro. Am. J. Physiol. 251:G487-G494.
45. Bandyopadhyay, G.K., W. Imagawa, D.R. Wallace, and S. Nandi. 1988. Proliferative effects of insulin and epidermal growth factor on mouse mammary epithelial cells in primary culture. J. Biol. Chem. 263:7567-7573.
46. Logsdon, C.D., J. Moessner, J.A. Williams, and I.D. Goldfine. 1985. Glucocorticoids increase amylase mRNA levels, secretory organelles, and secretion in pancreatic acinar AR42J cells. J. Cell Biol. 100:1200-1208.
47. Singh, J. 1983. Effects of amino acids, glucagon, insulin and acetylcholine on cyclic nucleotide metabolism and amylase secretion in isolated mouse pancreatic fragments. Biochem. Pharmacol. 32:2017-2023.
48. Soling, H.D., and K.O. Unger. 1972. The role of insulin in the regulation of amylase synthesis in the rat pancreas. Eur. J. Clin. Invest. 2:199-212.
49. Singh, J. 1985. Mechanism of action on acetylcholine-evoked amylase secretion in the mouse pancreas. J. Physiol. (Lond.). 358:469-482.