Progression of renal failure after subtotal nephrectomy in transgenic rats carrying an additional renin gene [TGR(mREN2)27]

Journal of Hypertension

Volumn 15, Issue 4, 1997, Pages 441-449

  Wagner, Jürgen ^a,d   Klotz, Susanne ^a   Haufe, Christophe C ^a   Danser, Jan A H ^b   Amann, Kerstin ^a   Ganten, Detlev ^c   Ritz, Eberhard ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b University of Rotterdam   (Germany)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Gene expression; Kidney; Renal failure; Renin angiotensin system; Transgenic animals

Indexed keywords

ANGIOTENSIN; DIPEPTIDYL CARBOXYPEPTIDASE; MESSENGER RNA; PRORENIN; RENIN;

ANIMAL EXPERIMENT; ARTICLE; BLOOD LEVEL; BLOOD PRESSURE; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE; GENE CONTROL; GENE EXPRESSION; GLOMERULOSCLEROSIS; INULIN CLEARANCE; KIDNEY; KIDNEY FAILURE; NONHUMAN; OVARIECTOMY; PARTIAL NEPHRECTOMY; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SPONTANEOUSLY HYPERTENSIVE RAT; TRANSGENIC ANIMAL;

EID: 0030902168     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-199715040-00015     Document Type: Article

References (41)

1. Anderson S, Rennke HG, Brenner BM: Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat. J Clin Invest 1986, 77:1993-1999.
2. Maki DD, Ma JZ, Louis TA, Kasiske BL: Long-term effects of antihypertensive agents on proteinuria and renal function. Arch Intern Med 1995, 155:1073-1080.
3. Maschio G, Alberti D, Janin G, Locatelli F, Mann JF, Motolese M, et al.: Effect of the angiotensin-converting-enzyme inhibitor benazepril on the progression of chronic renal insufficiency. The Angiotensin Converting-Enzyme Inhibition in Progressive Renal Insufficiency Study Group. N Engl J Med 1996, 334:939-945.
4. Lafayette RA, Mayer G, Park SK, Meyer TW: Angiotensin II receptor blockade limits glomerular injury in rats with reduced renal mass. J Clin Invest 1992, 91:766-771.
5. Scholey JW, Miller PL, Rennke HG, Meyer TW: Effect of converting enzyme inhibition on the course of adriamycin-induced nephropathy. Kidney Int 1989, 36:816-822.
6. Björk S, Nyberg G, Mulec H, Granerus G, Herlitz H, Aurell M: Beneficial effects of angiotensin converting enzyme inhibition on renal function in patients with diabetic nephropathy. BMJ 1986, 293:471-474.
7. Kamper AL, Strandgaard S, Leyssac PP: Effect of enalapril on the progression of chronic renal failure. A randomized controlled trial. Am J Hypertens 1992, 5:423-430.
8. Hostetter TH: Mechanisms of diabetic nephropathy. Am J Kidney Dis 1992, 23:188-192.
9. Rosenberg ME, Kren SM, Hostetter TH: Effect of dietary protein on the renin-angiotensin system in the rat in subtotally nephrectomised rats. Kidney Int 1990, 38:240-248.
10. Wagner J, Stein G, Mann J, Ritz E: Influence of dietary factors on the renal renin-angiotensin system. Klin Wochenschr 1992, 69 (suppl 29):35-38.
11. Amann K, Irzyniec T, Mall G, Ritz E: The effect of enalapril on glomerular growth and glomerular lesions after subtotal nephrectomy in the rat: a stereological analysis. J Hypertens 1993, 11:969-975.
12. Anderson PW, Do YS, Hsueh WA: Angiotensin II causes mesangial cell hypertrophy. Hypertension 1993, 21:29-35.
13. Raij L, Shultz PJ, Tolins PJ: Possible mechanism for the renoprotective effect of angiotensin converting enzyme inhibitors. J Hypertens 1989, 7 (suppl 4):S33-S37.
14. Bachmann S, Peters J, Engler E, Ganten D, Mullins J: Transgenic rats carrying the mouse renin gene-morphological characterization of a low renin hypertension model. Kidney Int 1992, 41:24-36.
15. Mullins JJ, Peters J, Ganten D: Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene. Nature 1990, 344: 541-544.
16. Möhring J, Petri M, Szokol M, Haack D, Möhring B: Effects of saline drinking on malignant course of renal hypertension in rats. Am J Physiol 1976, 230:849-857.
17. Wagner J, Wystrychowski A, Strauss H, Ganten D, Ritz E: Decreased haemodynamic response to inhibition of nitric oxide synthase in subtotally nephrectomized rats. Europ J Physiol 1995, 426: 1001-1006.
18. Horst P, Veelken R, Unger T: A new method for collecting urine directly from the ureter in conscious unrestrained rats. Renal Physiol Biochem 1988, 11:902-908.
19. Rettig R, Folberth C, Stauss H, Kopf D, Waldherr R, Unger T: Role of the kidney in primary hypertension: a renal transplantation study in rats. Am J Physiol 1990, 258:F606-F611.
20. Irzyniec T, Greber D, Ritz E, Mall G: Beneficial effects of nifedipine and moxonidine on glomerulosclerosis in SHR - a micromorphometric study. Am J Hypertens 1992, 5:437-443.
21. Bach G: Kugelgrößenverteilung und Verteilung der Schnittkreise; ihre wechselseitigen Beziehungen und Verfahren zur Bestimmung der einen aus de anderen. In Quantitative Methods in Morphology. Edited by Weibel E, Elias H. Berlin: Springer Verlag; 1967:23-45.
22. Raij L, Azar S, Keane W: Mesangial immune injury, hypertension and progressive glomerular damage in Dahl rats. Kidney Int 1984, 26:137-143.
23. Wiest G, Gharehbaghi H, Amann K, Simon T, Mattfeldt T, Mall G: Physiological growth of arteries in the rat heart parallels the growth of capillaries, but not of myocytes. J Mol Cell Cardiol 1992, 24:1423-1431.
24. DeHoff RT. Rhines FN: Determination of the number of particles per unit volume from measurements made on random plane sections: the general cylinder and the ellipsoid. Trans AIME 1961, 221: 975-1002.
25. Weibel ER: Stereological Methods. 1. Practical Methods for Biological Morphology. London: Academic Press; 1979.
26. Bohle A, Ratschek M: The compensated and decompensated form of benign nephrosclerosis. Path Res Pract 1982, 174:357-367.
27. Auffray C, Rougeon F: Purification of mouse immunoglobulin heavy chain mRNAs from total myeloma tumor RNA. Eur J Biochem 1980, 107:303-314.
28. Goedert M, Spillantini MG, Potier MC, Ulrich J, Crowther RA: Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain. EMBO J 1989, 8:393-399.
29. Hirsch AT, Talsness CE, Schunkert H, Paul M, Dzau VJ: Tissue-specific activation of cardiac angiotensin converting enzyme in experimental heart failure. Circ Res 1991, 69:475-482.
30. Glorioso N, Maddedu P, Dessi-Fulgheri P, Fois G, Meloni F, Bandiera G, et al.: Trypsin-activatable inactive renin in rat plasma. Clin Sci (Lond) 1983, 64:137-140.
31. Schelling P, Ganten U, Sponer G, Unger T, Ganten D: Components of the renin-angiotensin system in the cerebrospinal fluid of rats and dogs with special consideration of the origin and the fate of angiotensin II. Neuroendocrinology 1980, 31:297-308.
32. Mülller DN, Hilgers KF, Bohlender J, Lippoldt A, Wagner J, Fischli W, et al.: Effects of human renin in the vasculature of rats transgenic for human angiotensinogen. Hypertension 1995, 26:272-278.
33. Danser AHJ, van Kats JP, Admiraal PJJ, Derkx FHM, Lamers JMJ, Verdouw PD: Cardiac renin and angiotensins: uptake from plasma versus in situ synthesis. Hypertension 1994, 24:37-48.
34. Nussberger J, Nicoud F, Brunner D, Evequoz D, Brunner HR: Measurement of low angiotensin II concentrations in rat hearts. Hypertension 1991, 18:384.
35. Unger Th, Ganten D, Lang RE, Schölkens BA: Persistent tissue converting enzyme inhibition following chronic treatment with Hoe 498 and MK 421 on spontaneously hypertensive rats. J Cardiovasc Pharmacol 1985, 7:36-41.
36. Bidani AK, Griffin KA, Picken M, Lansky DM: Continuous telemetric blood pressure monitoring and glomerular injury in the rat remnant kidney model. Am J Physiol 1993, 265:F391-F398.
37. Ioannou P, Loh AY, Osmond DM: Activation and measurement of plasma prorenin in the rat. Can J Physiol Pharmacol 1991, 69:1331-1340.
38. Guan S, Fox J, Mitchell KD, Navar LG: Angiotensin and angiotensin converting enzyme tissue levels in two-kidney, one clip hypertensive rats. Hypertension 1992, 20:763-767.
39. Leith R, Salgado M: Increased vascular formation of angiotensin II in one kidney, one clip hypertension. Hypertension 1992. 19:575-581
40. Correa-Rotter R, Hosteller TH, Manivel JC, Rosenberg ME: Renin expression in renal ablation. Hypertension 1992, 20:483-490.
41. Rosenberg ME, Correa-Rotter R, Inagami T, Kren SM, Hostetter TH: Glomerular renin synthesis and storage in the remnant kidney in the rat Kidney Int 1991, 40:677-683.