V170 area plays an essential role in the biological activity of human ciliary neurotrophic factor

Journal of Neurochemistry

Volumn 68, Issue 4, 1997, Pages 1436-1442

  Inoue, Makoto ^a   Karita, Hiromi ^a   Kikuchi, Kaoru ^a   Nakayama, Chikao ^a   Noguchi, Hiroshi ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

Ciliary neurotrophic factor; Cytokine; Four helix bundle; gp130; Mutagenesis; Structure function relationship

Indexed keywords

CILIARY NEUROTROPHIC FACTOR;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; HUMAN; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FOLDING; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

EID: 0030901268     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.68041436.x     Document Type: Article

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