Plant farnesyltransferase can restore yeast Ras signaling and mating

Molecular and Cellular Biology

Volumn 17, Issue 4, 1997, Pages 1986-1994

  Yalovsky, S ^a   Trueblood, C E ^b   Callan, K L ^a   Narita, J O ^a,c   Jenkins, S M ^a   Rine, J ^b   Gruissem, W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPRENOID; PROTEIN FARNESYLTRANSFERASE; RAS PROTEIN;

ARTICLE; BIOSYNTHESIS; EUKARYOTE; EVOLUTION; GENETIC CONSERVATION; MATING; NONHUMAN; ONCOGENE RAS; PLANT; PRIORITY JOURNAL; PROTEIN MODIFICATION; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TOMATO; YEAST;

EUKARYOTA; INSECTA; LYCOPERSICON ESCULENTUM; MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0030899810     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.4.1986     Document Type: Article

References (57)

1. Anant, J. S., O. C. Ong, H. Xie, S. Clarke, P. J. O'Brien, and B. K. K. Fung. 1992. In vivo differential prenylation of retinal cyclic GMP phosphodiesterase catalytic subunits. J. Biol. Chem. 267:687-690.
2. Anderegg, R. J., R. Betz, S. A. Carr, J. W. Crabb, and W. Duntze. 1988. Structure of the Saccharomyces cerevisiae mating hormone a-factor: identification of S-farnesyl cysteine as a structural component. J. Biol. Chem. 263: 18236-18240.
3. Ashby, M. N., P. R. Errada, V. L. Boyartchuk, and J. Rine. 1993. Isolation and DNA sequence of the STE14 gene encoding farnesyl cysteine:carboxyl methyltransferase. Yeast 9:907-913.
4. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1995. Current protocols in molecular biology. John Wiley & Sons, Inc., New York, N.Y.
5. Biermann, B. J., T. A. Morehead, S. E. Tate, J. R. Price, S. K. Randall, and D. N. Crowell. 1994. Novel isoprenylated proteins identified by an expression library screen. J. Biol. Chem. 269:25251-25254.
6. Boeke, J. D., F. LaCroute, and G. R. Fink. 1984. A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol. Gen. Genet. 197:345-346.
7. Boeke, J. D., J. Trueheart, G. Natsoulis, and G. R. Fink. 1987. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 154:164-175.
8. Boguski, M. S., A. W. Murray, and S. Powers. 1992. Novel repetitive sequence motifs in the α and β subunits of prenyl-protein transferases and homology of the α subunit to the MAD2 gene product of yeast. New Biol. 4:408-411.
9. Caplan, A. J., J. Tsai, P. J. Casey, and M. G. Douglas. 1992. Farnesylation of YDJ1p is required for function at elevated growth temperatures in Saccharomyces cerevisiae. J. Biol. Chem. 267:18890-18895.
10. Caplin, B. E., L. A. Hettich, and M. S. Marshall. 1994. Substrate characterization of the Saccharomyces cerevisiae protein farnesyltransferase and type-I protein geranylgeranyltransferase. Biochim. Biophys. Acta 1205:39-48.
11. 21ras is modified by a farnesyl isoprenoid. Proc. Natl. Acad. Sci. USA 86:8323-8327.
12. Chan, R. K., and C. A. Otte. 1982. Isolation and genetic analysis of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a factor and α factor pheromones. Mol. Cell. Biol. 2:11-20.
13. 21 ras farnesyltransferase, the counterpart of the yeast DPR1/RAM1. Cell 66:327-334.
14. Cutler, S., M. Ghassemian, D. Bonetta, S. Cooney, and P. McCourt. 1996. A protein farnesyl transferase involved in ABA signal transduction in Arabidopsis. Science 273:1239-1241.
15. Deschenes, R. J., J. B. Stimmel, S. Clarke, J. Stock, and J. R. Broach. 1989. RAS2 protein of Saccharomyces cerevisiae is methyl-esterified at its carboxyl terminus. J. Biol. Chem. 264:11865-11873.
16. De Smedt, F., A. Boom, X. Pesesse, S. N. Schiffmann, and C. Erneux. 1996. Post-translational modification of human brain type I inositol-1,4,5-trisphosphate 5-phosphatase by farnesylation. J. Biol. Chem. 271:10419-10424.
17. Emr, S. D., A. Vassarotti, J. Garrett, B. L. Geller, M. Takeda, and M. G. Douglas. 1986. The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal. J. Cell Biol. 102:523-533.
18. Fukada, Y., T. Takao, H. Ohguro, T. Yoshizawa, T. Akino, and Y. Shimonishi. 1990. Farnesylated γ-subunit of photoreceptor G protein indispensible for GTP binding. Nature (London) 346:658-660.
19. Gietz, R. D., and A. Sugino. 1988. New yeast and Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74:527-534.
20. Goldstein, J. L., and M. S. Brown. 1990. Regulation of the mevalonate pathway. Nature (London) 343:425-430.
21. Goodman, L. E., C. M. Perou, A. Fujiyama, and F. Tamanoi. 1988. Structure and expression of yeast DPR1, a gene essential for the processing and intracellular localization of ras proteins. Yeast 4:271-281.
22. Gutierrez, L., A. I. Magee, C. J. Marshall, and J. F. Hancock. 1989. Post-translational processing of p21ras is two-step and involves carboxyl-methylation and carboxyl-terminal proteolysis. EMBO J. 8:1093-1098.
23. Hancock, J. F., A. I. Magee, J. E. Childs, and C. J. Marshall. 1989. All ras proteins are polyisoprenylated but only some are palmitoylated. Cell 57: 1167-1177.
24. He, B., P. Chen, S.-Y. Chen, K. L. Vancura, S. Michaelis, and S. Powers. 1991. RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins. Proc. Natl. Acad. Sci. USA 88:11373-11377.
25. Inglese, J., W. J. Koch, M. G. Caron, and K. J. Lefkowitz. 1992. Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases. Nature (London) 359:147-150.
26. Inglese, J., W. J. Koch, M. G. Caron, and R. J. Lekowitz. 1992. Isoprenylation of a protein kinase: requirement of farnesylation/α-carboxyl methylation for full enzymatic activity of rhodopsin kinase. J. Biol. Chem. 267:1422-1425.
27. Ito, H., Y. Fukuda, K. Murata, and A. Kimura. 1983. Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153:163-168.
28. Kamiya, Y., A. Sakurai, S. Tamura, N. Takahashi, K. Abe, E. Tsuchiya, S. Fukui, C. Kitada, and M. Fujino. 1978. Structure of the rhodotorucine A, a novel lipopeptide, inducing mating tube formation in Rhodosporidium toruloides. Biochem. Biophys. Res. Commun. 83:1077-1083.
29. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680-685.
30. Lai, R. K., D. Perez-Sala, F. J. Canada, and R. R. Rando. 1990. The γ subunit of transducin is farnesylated. Proc. Natl. Acad. Sci. USA 87:7673-7677.
31. Mayer, M. L., B. E. Caplin, and M. S. Marshall. 1992. CDC43 and RAM2 encode the polypeptide subunits of yeast type I protein geranylgeranyltransferase. J. Biol. Chem. 267:20589-20593.
32. Moores, S. L., M. D. Schaber, S. D. Mosser, E. Rands, M. B. O'Hara, V. M. Garsky, M. S. Marshall, D. L. Pompliano, and J. B. Gibbs. 1991. Sequence dependence of protein isoprenylation. J. Biol. Chem. 266:14603-14610.
33. Morehead, T. A., B. J. Biermann, D. N. Crowell, and S. K. Randall. 1995. Changes in protein isoprenylation during growth of suspension-cultured tobacco cells. Plant Physiol. 109:277-284.
34. Narita, J. Unpublished data.
35. Omer, C. A., and J. B. Gibbs. 1994. Protein prenylation in eukaryotic microorganisms: genetics, biology and biochemistry. Mol. Microbiol. 11:219-225.
36. O'Reilly, D. R., L. K. Miller, and V. A. Luckow. 1992. Baculovirus expression vectors. A laboratory manual. W. H. Freeman and Company, New York, N.Y.
37. Otto, J. C., and P. J. Casey. 1996. The hepatitis delta virus large antigen is farnesylated both in vitro and in animal cells. J. Biol. Chem. 271:4569-4572.
38. Pompliano, D. L., M. D. Schaber, S. D. Mosser, C. A. Omer, J. A. Shafer, and J. B. Gibbs. 1993. Isoprenoid diphosphate utilization by recombinant human farnesyl:protein transferase: interactive binding between substrates and a preferred kinetic pathway. Biochemistry 32:8341-8347.
39. Randall, S. K., M. S. Marshall, and D. N. Crowell. 1993. Protein isoprenylation in suspension-cultured tobacco cells. Plant Cell 5:433-442.
40. Reiss, Y., M. S. Brown, and J. L. Goldstein. 1992. Divalent cation and prenyl pyrophosphate specificities of the protein farnesyltransferase from rat brain, a zinc metalloenzyme. J. Biol. Chem. 267:6403-6408.
41. 21 ras farnesyl transferase by Cys-AAX tetrapeptides. Cell 62:81-88.
42. H-ras farnesyltransferase. J. Biol. Chem. 266:10672-10677.
43. ras protein farnesyltransferase. Proc. Natl. Acad. Sci. USA 88:732-736.
44. Sakagami, Y., M. Yoshida, A. Isogai, and A. Suzuki. 1981. Peptidal sex hormones inducing conjugation tube formation in compatible mating-type cells of Tremella mesenterica. Science 212:1525-1527.
45. Schafer, W. R., and J. Rine. 1992. Protein prenylation: genes, enzymes, targets and functions. Annu. Rev. Genet. 30:209-237.
46. Schafer, W. R., C. E. Trueblood, C.-C. Yang, M. P. Mayer, S. Rosenberg, C. D. Poulter, S.-H. Kim, and J. Rine. 1990. Enzymatic coupling of cholesterol intermediates to a mating pheromone precursor and to the Ras protein. Science 249:1133-1139.
47. Schena, M., D. Picard, and K. R. Yamamoto. 1991. Vectors for constitutive and inducible gene expression in yeast. Methods Enzymol. 194:389-398.
48. Schmitt, D., K. Callan, S.-H. Kim, and W. Gruissem. 1996. Molecular and biochemical characterization of tomato farnesyl-protein transferase. Plant Physiol. 112:767-777.
49. Seabra, M. C., Y. Reiss, P. Casey, M. S. Brown, and J. L. Goldstein. 1991. Protein farnesyltransferase and geranylgeranyltransferase share a common α subunit. Cell 65:429-434.
50. Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
51. Stotz, A., and P. Linder. 1990. The ADE2 gene from Saccharomyces cerevisiae: sequence and new vectors. Gene 95:91-98.
52. Trueblood, C. E., Y. Ohya, and J. Rine. 1993. Genetic evidence for in vivo cross-specificity of the CaaX-box protein prenyltransferases farnesyltransferase and geranylgeranyltransferase-I in Saccharomyces cerevisiae. Mol. Cell. Biol. 13:4260-4275.
53. Wolda, S. L., and J. A. Glomset. 1988. Evidence for modification of lamin B by a product of mevalonic acid. J. Biol. Chem. 263:5997-6000.
54. Yang, Z., C. L. Cramer, and J. C. Watson. 1993. Protein farnesyltransferase in plants. Molecular cloning and expression of a homolog of the beta subunit from the garden pea. Plant Physiol. 101:667-674.
55. Yasuda, H., M. A. Lindorfer, K. A. Woodfork, J. E. Fletcher, and J. C. Garrison. 1996. Role of the prenyl group on the G protein γ subunit in coupling trimeric G proteins to A1 adenosine receptors. J. Biol. Chem. 271:18588-18595.
56. Ying, W., L. Sepp-Lorenzino, K. Cai, P. Aloise, and P. Coleman. 1994. Photoaffinity-labeling peptide substrates for farnesyl-protein transferase and the intersubunit location of the active site. J. Biol. Chem. 269:470-477.
57. Zhu, J.-K., R. A. Bressan, and P. M. Hasegawa. 1993. Isoprenylation of the plant molecular chaperone ANJ1 facilitates membrane association and function at high temperature. Proc. Natl. Acad. Sci. USA 90:8557-8561.