Frequent alterations in gene expression in colon tumor cells of the microsatellite mutator phenotype

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 374, Issue 2, 1997, Pages 153-167

  Ricote, Mercedes ^a,b   Geller, Patricia ^a,c   Perucho, Manuel ^a  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COLON TUMOR; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; SOMATIC MUTATION; TUMOR CELL;

BLOTTING, NORTHERN; BLOTTING, SOUTHERN; CLONE CELLS; CLONING, MOLECULAR; COLORECTAL NEOPLASMS; DNA PRIMERS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYBRID CELLS; MICROSATELLITE REPEATS; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RNA; TUMOR CELLS, CULTURED;

EID: 0030897989     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(97)00002-X     Document Type: Article

References (45)

1. Ionov, Y., M.A. Peinado, S. Malkhosyan, D. Shibata and M. Perucho (1993) Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis, Nature, 363, 558-561.
2. Loeb, L.A. (1994) Microsatellite instability: marker of a mutator phenotype in cancer, Cancer Res., 54, 5059-5063.
3. Kolodner, R.D. (1995) Mismatch repair: mechanisms and relationship to cancer susceptibility, Trends Biochem. Sci., 20, 397-401.
4. Marra, G. and C.R. Boland (1995) Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives, J. Natl. Cancer Inst., 87, 1114-1125.
5. Perucho, M. (1996) Cancer of the microsatellite mutator phenotype, Biol. Chem., 377, 675-684.
6. Fearon, E.R. and B. Vogelstein (1990) A genetic model for colorectal tumorigenesis, Cell, 61, 759-767.
7. Kim, H., J. Jen, B. Vogelstein and S.R. Hamilton (1994) Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences, Am. J. Pathol., 145, 148-156.
8. Markowitz, S., J. Wang, L. Myeroff, R. Parsons, L. Sun, J. Lutterbaugh, R.S. Fan, E. Zborowska, K.W. Kinzler and B. Vogelstein (1995) Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability, Science, 268, 1336-1338.
9. Perucho, M. (1996) The mutator that mutates the other mutator, Nature Med., 2, 630-631.
10. Welsh, J. and M. McClelland (1990) Fingerprinting genomes using PCR with arbitrary primers, Nucleic Acids Res., 18, 7213-7218.
11. Williams, J.G., A.R. Kubelik, K.J. Livak, J.A. Rafalski and S.V. Tingey (1990) DNA polymorphisms amplified by arbitrary primers are useful as genetic markers, Nucleic Acids Res., 18, 6531-6535.
12. Welsh, J., K. Chada, S.S. Dalal, R. Cheng, D. Ralph and M. McClelland (1992) Arbitrarily primed PCR fingerprinting of RNA, Nucleic Acids Res., 20, 4965-4970.
13. Liang, P. and A.B. Pardee (1992) Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction, Science, 257, 967-971.
14. Liang, P. and A.B. Pardee (1995) Recent advances in differential display, Curr. Opin. Immunol., 7, 274-280.
15. McClelland, M., F. Mathieu-Daude and J. Welsh (1995) RNA fingerprinting and differential display using arbitrarily primed PCR, Trends Genet., 11, 242-246.
16. Peinado, M.A., S. Malkhosyan, A. Velazquez and M. Perucho (1992) Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction, Proc. Natl. Acad. Sci. USA, 89, 10065-10069.
17. Shibata, D., M.A. Peinado, Y. Ionov, S. Malkhosyan and M. Perucho (1994) Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation, Nature Genet., 6, 273-281.
18. Casares, S., Y. lonov, H.Y. Ge, E. Stanbridge and M. Perucho (1995) The microsatellite mutator phenotype of colon cancer cells is often recessive, Oncogene, 11, 2303-2310.
19. Malkhosyan, S., A. McCarty, H. Sawai and M. Perucho (1996) Differences in the spectrum of spontaneous mutations in the HPRT gene between tumor cells of the microsatellite mutator phenotype, Mutation Res., 316, 249-259.
20. Boyer, J.C., A. Umar, J.I. Risinger, J.R. Lipford, M. Kane, S. Yin, J.C. Barrett, R.D. Kolodner and T.A. Kunkel (1995) Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines, Cancer Res., 55, 6063-6070.
21. Papadopoulos, N., N.C. Nicolaides, B. Liu, R. Parsons, C. Lengauer, F. Palombo, A. D'Arrigo, S. Markowitz, J.K. Willson and K.W. Kinzler (1995) Mutations of GTBP in genetically unstable cells, Science, 268, 1915-1917.
22. Malkhosyan, S., N. Rampino, H. Yamamoto and M. Perucho (1996) Frameshift mutator mutations, Nature, 382, 499-500.
23. Umar, A., J.C. Boyer, D.C. Thomas, D.C. Nguyen, J.I. Risinger, J. Boyd, Y. lonov, M. Perucho and T.A. Kunkel (1994) Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability, J. Biol. Chem., 269, 14367-14370.
24. + tumor cells, Cell, 75, 1227-1236.
25. Perucho, M., J. Welsh, M.A. Peinado, Y. Ionov and M. McClelland (1995) Fingerprinting of DNA and RNA by arbitrarily primed polymerase chain reaction: applications in cancer research, Methods Enzymol., 254, 275-290.
26. Chirgwin, J.M., A.E. Przybyla, R.J. MacDonald and W.J. Rutter (1979) Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease, Biochemistry, 18, 5294-5299.
27. Yasuda, J., M. Navarro, S. Malkhosyan, A. Velazquez, T. Seikya and M. Perucho (1996) Chromosomal assignment of human DNA fingerprint sequences by simultaneous hybridization to Arbitrarily Primed PCR products from human/rodent monochromosome cell hybrids, Genomics, 34, 1-7.
28. Maniatis, T., E.F. Fritsch and J. Sambrook (1982) Molecular Cloning: a Laboratory Manual, Cold Spring Harbor, New York.
29. Young, J.A. and J. Trowsdale (1985) A processed pseudogene in an intron of the HLA-DP beta 1 chain gene is a member of the ribosomal protein L32 gene family, Nucleic Acids Res., 13, 8883-8891.
30. Mager, D.L. and J.D. Freeman (1987) Human endogenous retroviruslike genome with type C pol sequences and gag sequences related to human T-cell lymphotropic viruses, J. Virol., 61, 4060-4066.
31. Hillier, L., N. Clark, T. Dubuque, K. Elliston, M. Hawkins, M. Holman, M. Hultman, T. Kucaba, M. Le, G. Lennon, M. Marra, J. Parsons, L. Rifkin, T. Rohfing, M. Soares, F. Tan, E. Trevaskis, R. Waterson, A. Williamson, P. Wohldmann and R. Wilson (1995) The Washu-Merck EST Project. Available through the GenBank Database.
32. Hirose, Y., M. Takamatsu and F. Harada (1993) Presence of env genes in members of the RTVL-H family of human endogenous retrovirus-like elements, Virology, 192, 52-61.
33. Bhattacharyya, N.P., A. Skandalis, A. Ganesh, J. Groden and M. Meuth (1994) Mutator phenotypes in human colorectal carcinoma cell lines, Proc. Natl. Acad. Sci. USA, 91, 6319-6323.
34. Eshleman, J.R., E.Z. Lang, G.K. Bowerfind, R. Parsons, B. Vogelstein, J.K. Willson, M.L. Veigl, W.D. Sedwick and S.D. Markowitz (1995) Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer, Oncogene, 10, 33-37.
35. Brattain, M.G., W.D. Fine, F.M. Khaled, J. Thompson and D.E. Brattain (1981) Heterogeneity of malignant cells from a human colonic carcinoma, Cancer Res., 41, 1751-1756.
36. Koi, M., A. Umar, D.P. Chauhan, S.P. Cherian, J.M. Carethers, T.A. Kunkel and C.R. Boland (1994) Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozy-gous hMLH1 mutation, Cancer Res., 54, 4308-4312.
37. Bodmer, W., T. Bishop and P. Karran (1994) Genetic steps in colorectal cancer, Nature Genet., 6, 217-219.
38. Leith, J.T. and D.L. Dexter (1996) Mammalian Tumor Cell Heterogeneity, CRC Press, Boca Raton, FL.
39. Harwood, J., A. Tachibana and M. Meuth (1991) Multiple dispersed spontaneous mutations: a novel pathway of mutation in a malignant human cell line, Mol. Cell. Biol., 11, 3163-3170.
40. Lower, R., J. Lower and R. Kurth (1996) The viruses in all of us: characteristics and biological significance of human endogeneous retrovirus sequences, Proc. Natl. Acad. Sci. USA, 93, 5177-5184.
41. Bouton, A.H. and J.T. Parsons (1993) Retroviruses and cancer: models for cancer in animals and humans, Cancer Invest., 11, 70-79.
42. Kaplan, M.H. (1993) Human retroviruses and neoplastic disease, Clin. Infect. Dis., 17, Suppl. 2, S400-S406.
43. Welsh, J., N. Rampino, M. McClelland and M. Perucho (1995) Nucleic acid fingerprinting PCR-based methods: applications to problems in mutagenesis and aging, Mutation Res., 338, 215-219.
44. Tuite, M. (1996) Death by decapitation for mRNA, Nature, 382, 577-579.
45. Rampino, N., H. Yamamoto, Y. Ionov, Y. Li, Sawai, J.C. Reed and M. Perucho (1997) Somatic frameshift mutations in the Bax gene in colon cancer of the microsatellite mutator phenotype, Science, in press.