Cytolytic and tumor inhibitory antibodies against UK114 protein in the sera of cancer patients

International Journal of Oncology

Volumn 10, Issue 4, 1997, Pages 779-785

  Bussolati, Gianni ^a   Geuna, Massimo ^a   Bussolati, Benedetta ^b   Millesimo, Maura ^a   Botta, Marinella ^c   Bartorelli, Alberto ^c  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Antibodies; Cytotoxicity; Immunofluorescence; Neoplasms

Indexed keywords

PROTEIN UK114; TUMOR MARKER; UK114 ANTIBODY; UNCLASSIFIED DRUG;

ANTIBODY BLOOD LEVEL; ARTICLE; CANCER PATIENT; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; PRIORITY JOURNAL;

EID: 0030897962     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.10.4.779     Document Type: Article

References (11)

1. Bartorelli A, Biancardi C, Cavalca V, Ferrara R, Botta M, Arzani C, Colombo I, Berra B, Ceciliani F, Ronchi S and Bailo M: Purification and partial characterization of proteins present in a perchloric acid extract of goat liver cross-reacting with human tumor. J Tumor Marker Oncol 11: 57-61, 1996.
2. Ceciliani F, Faotto L, Negri A, Colombo I, Berra B, Bartorelli A and Ronchi S: The primary structure of UK114 tumor antigen. FEBS Lett 393: 147-150, 1996.
3. Levy-Favatier F, Cuisset L, Nedelec B, Tichonicky L, Kruh J and Delpech M: Characterization, purification and cDNA cloning of a rat perchloric-acid-soluble 23-kDa protein present only in liver and kidney. J Biochem 212: 665-673, 1993.
4. Oka T, Tsuji H, Noda C, Sakai K, Hong Y, Suzuki I, Munoz S and Natori Y: Isolation and characterization of a novel perchloric acid-soluble protein inhibiting cell-free protein synthesis. J Biol Chem 270: 30060-30067, 1995.
5. Bartorelli A, Berra B, Ronchi S, Biancardi C, Cavalca V, Bailo M, Mor C, Ferrara R, Botta M, Arzani C and Clemente C: Immunocytochemical reactivity of mammalian liver antigen (UK101) in human tumors and non neoplastic tissues. J Tumor Marker Oncol 9: 37-47, 1994.
6. Bartorelli A, Bussolati B, Millesimo M, Gugliotta P and Bussolati G: Antibody-dependent cytotoxic activity on human cancer cells expressing UK114 tumor membrane antigen. Int J Oncol 8: 543-548, 1996.
7. Ferrarini M, Heltai S, Zocchi MR and Rugarli C: Unusual expression and localization of heat-shock proteins in human tumor cells. Int J Cancer 51: 613-619, 1992.
8. Chouchane L, Bowers FS, Sawasdikosol S, Simpson RM and Kindt TJ: Heat-shock proteins expressed on the surface of human T cell leukemia virus type I-infected cell lines induce autoantibodies in rabbits. J Infect Dis 169: 253-259, 1994.
9. Multhoff G, Botzler C, Wiesnet M, Müller E, Meier T, Wilmanns W and Issels RD: A stress-inducible 72-kDa heat-shock protein (HSP72) is expressed on the surface of human tumor cells, but not on normal cells. Int J Cancer 61: 272-279, 1995.
10. Tamura Y, Tsuboi N, Sato N and Kikuchi K: 70-kDa heat-shock cognate protein is a transformation-associated antigen and a possible target for the host's anti-tumor immunity. J Immunol 151: 5516-5524, 1993.
11. Udono H and Srivastava PK: Heat-shock protein 70-associated peptides elicit specific cancer immunity. J Exp Med 178: 1391-1396, 1993.