Pretreatment with L-kynurenine, the precursor to the excitatory amino acid antagonist kynurenic acid, suppresses epileptiform activity in combined entorhinal/hippocampal slices

Neuroscience Letters

Volumn 224, Issue 2, 1997, Pages 115-118

  Scharfman, Helen E ^a   Ofer, Adam ^a  

^a HELEN HAYES HOSPITAL   (United States)

Author keywords

anticonvulsant; epilepsy; excitatory amino acid; glia; magnesium; N methyl D aspartate; neurotox icity; seizure; tryptophan

Indexed keywords

ANTICONVULSIVE AGENT; GLUTAMATE RECEPTOR ANTAGONIST; KYNURENIC ACID; KYNURENINE; MAGNESIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ENTORHINAL CORTEX; EPILEPSY; FEMALE; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTICONVULSANTS; BUFFERS; ELECTROPHYSIOLOGY; ENTORHINAL CORTEX; EPILEPSY; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; HIPPOCAMPUS; KYNURENIC ACID; KYNURENINE; MAGNESIUM; MALE; ORGAN CULTURE TECHNIQUES; PROTEIN PRECURSORS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030893665     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(97)13472-3     Document Type: Article

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