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Volumn 62, Issue 6, 1997, Pages 1610-1616

Diyl trapping reactions to synthesize taxol analogs

Author keywords

[No Author keywords available]

Indexed keywords

TAXANE DERIVATIVE;

EID: 0030891818     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo970042e     Document Type: Article
Times cited : (17)

References (26)
  • 12
    • 84920292918 scopus 로고    scopus 로고
    • note
    • The sequence leading from 9 to 10 was originally explored and developed by Mr. Scott Meehan of UCSB. The use of DMSO allowed the chemistry to be conducted at room temperature, made the process very convenient to conduct, and led to significantly improved yields. Details concerning the general procedure will be published elsewhere.
  • 15
    • 84920292917 scopus 로고    scopus 로고
    • The dimethyl ketal analog of diazene 6 proved too labile toward conversion to the corresponding ketone and was not useful
    • The dimethyl ketal analog of diazene 6 proved too labile toward conversion to the corresponding ketone and was not useful.
  • 26
    • 84920292916 scopus 로고    scopus 로고
    • SYBYL calculations consistently placed the trans-fused isomer at a substantially lower energy than the cis (>2 kcal/mol)
    • SYBYL calculations consistently placed the trans-fused isomer at a substantially lower energy than the cis (>2 kcal/mol).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.