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1
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0029655778
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Activation of proglucagon gene transcription through a novel promoter element by the caudal-related homeodomain protein cdx-2/3
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Jin T, Drucker DJ: Activation of proglucagon gene transcription through a novel promoter element by the caudal-related homeodomain protein cdx-2/3. Mol Cell Biol 1996, 96:19-28. Analysis of the proglucagon gene promoter demonstrating islet and enteroendocrine cell-specific expression is mediated by binding of cdx-2.
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(1996)
Mol Cell Biol
, vol.96
, pp. 19-28
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Jin, T.1
Drucker, D.J.2
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2
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0029914245
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The caudal-type homeobox protein Cdx-2 binds to the colon promoter of the carbonic anhydrase 1 gene
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Drummond F, Sowden J, Morrison K, Edwards YH: The caudal-type homeobox protein Cdx-2 binds to the colon promoter of the carbonic anhydrase 1 gene. Eur J Biochem 1996, 96:670-681. Identification of cdx-2 as the colon-specific factor that mediates expression of the carbonic anhydrase 1 gene.
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(1996)
Eur J Biochem
, vol.96
, pp. 670-681
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Drummond, F.1
Sowden, J.2
Morrison, K.3
Edwards, Y.H.4
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3
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0030032310
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An intestine-specific homeobox gene regulates proliferation and differentiation
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Suh E, Traber PG: An intestine-specific homeobox gene regulates proliferation and differentiation. Mol Cell Biol 1996, 96:619-625. This study demonstrates the role of cdx-2 in the regulation of two different cellular processes, proliferation and differentiation, in intestinal epithelium.
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(1996)
Mol Cell Biol
, vol.96
, pp. 619-625
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Suh, E.1
Traber, P.G.2
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4
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0029882707
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Dependence of epithelial growth of the small intestine on T-cell activation during weaning in the rat
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Thompson FM, Mayrhofer G, Cummins AG: Dependence of epithelial growth of the small intestine on T-cell activation during weaning in the rat Gastroenterology 1996, 11:37-44. This study provides evidence for the requirement of activated T cells in intestinal development.
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(1996)
Gastroenterology
, vol.11
, pp. 37-44
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Thompson, F.M.1
Mayrhofer, G.2
Cummins, A.G.3
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5
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0030048317
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Developmental regulation of transforming growth factor beta-mediated collagen synthesis in human intestinal muscle cells
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Perr H, Oh P, Johnson D: Developmental regulation of transforming growth factor beta-mediated collagen synthesis in human intestinal muscle cells. Gastroenterology 1996, 96:92-101. Immunohistological study demonstrating the synthesis of TGF-β in the smooth muscle cells of human fetal intestine.
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(1996)
Gastroenterology
, vol.96
, pp. 92-101
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Perr, H.1
Oh, P.2
Johnson, D.3
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6
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0029970132
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Acute epithelial injury in the rat small intestine in vivo is associated with expanded expression of transforming growth factor a and b
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Dignass AU, Stow JL, Babyatsky MW: Acute epithelial injury in the rat small intestine in vivo is associated with expanded expression of transforming growth factor a and b. Gut 1996, 38:687-693. Immunohistological study demonstrating the change in TGF-α and -β synthesis in the intestinal epithelial cells during acute injury.
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(1996)
Gut
, vol.38
, pp. 687-693
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Dignass, A.U.1
Stow, J.L.2
Babyatsky, M.W.3
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7
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0030044720
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Oral trefoil peptides protect against ethanol- and indomethacin-induced gastric injury in rats
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Babyatsky MW, deBeaumont M, Thim L, Podolsky DK: Oral trefoil peptides protect against ethanol- and indomethacin-induced gastric injury in rats. Gastroenterology 1996, 96:489-497. This study demonstrates a topical protective effect of human SP and rat ITF against in vivo gastric injury.
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(1996)
Gastroenterology
, vol.96
, pp. 489-497
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Babyatsky, M.W.1
DeBeaumont, M.2
Thim, L.3
Podolsky, D.K.4
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8
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0028894436
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Human spasmolytic polypeptide is a cytoprotective agent that stimulates cell migration
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Playford RJ, Marchbank T, Chinery R, Evison R, Pignatelli M, Boulton RA, Thim L, Hanby AM: Human spasmolytic polypeptide is a cytoprotective agent that stimulates cell migration. Gastroenterology 1995, 95:108-116.
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(1995)
Gastroenterology
, vol.95
, pp. 108-116
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Playford, R.J.1
Marchbank, T.2
Chinery, R.3
Evison, R.4
Pignatelli, M.5
Boulton, R.A.6
Thim, L.7
Hanby, A.M.8
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9
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0028935754
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Experimental ulceration leads to sequential expression of spasmolytic polypeptide, intestinal trefoil factor, epidermal growth factor and transforming growth factor alpha mRNAs in rat stomach
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Alison MR, Chinery R, Poulsom R, Ashwood P, Longcroft JM, Wright NA: Experimental ulceration leads to sequential expression of spasmolytic polypeptide, intestinal trefoil factor, epidermal growth factor and transforming growth factor alpha mRNAs in rat stomach. J Pathol 1995, 95:405-414. Expression of rat SP and rat ITF mRNA is induced in vivo following gastric injury.
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(1995)
J Pathol
, vol.95
, pp. 405-414
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Alison, M.R.1
Chinery, R.2
Poulsom, R.3
Ashwood, P.4
Longcroft, J.M.5
Wright, N.A.6
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10
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0028934298
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Combined intestinal trefoil factor and epidermal growth factor is prophylactic against indomethacin-induced gastric damage in the rat
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Chinery R, Playford RJ: Combined intestinal trefoil factor and epidermal growth factor is prophylactic against indomethacin-induced gastric damage in the rat Clin Sci (Colch) 1995, 95:401-403. This study demonstrates the synergistic effect of epidermal growth factor and rat ITF in protection against gastric injury.
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(1995)
Clin Sci (Colch)
, vol.95
, pp. 401-403
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Chinery, R.1
Playford, R.J.2
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11
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0030007366
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A third P-domain peptide gene (TFF3), human intestinal trefoil factor, maps to 21q22.3
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Schmitt H, Wundrack I, Beck S, Gott P, Welter C, Shizuya H, Simon MI, Blin N: A third P-domain peptide gene (TFF3), human intestinal trefoil factor, maps to 21q22.3. Cytogenet Cell Genet 1996, 96;72:299-302.
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(1996)
Cytogenet Cell Genet
, vol.96
, Issue.72
, pp. 299-302
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Schmitt, H.1
Wundrack, I.2
Beck, S.3
Gott, P.4
Welter, C.5
Shizuya, H.6
Simon, M.I.7
Blin, N.8
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12
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0029828745
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Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor
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Mashimo H, Wu DC, Podolsky DK, Fishman MC: Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor. Science 1996, 274:262-265. The role of ITF in the maintenance of the protective mucosal barrier is demonstrated by the increased susceptibility of ITF-deficient mice to mucosal injury.
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(1996)
Science
, vol.274
, pp. 262-265
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Mashimo, H.1
Wu, D.C.2
Podolsky, D.K.3
Fishman, M.C.4
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13
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10244252625
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Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein
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Lefebvre O, Chenard MP, Masson R, Linares J, Dierich A, LeMeur M, Wendling C, Tomasetto C, Chambon P, Rio MC: Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein. Science 1996, 274:259-262. The appearance of gastric adenomas and carcinomas in transgenic mice lacking the trefoil protein pS2.
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(1996)
Science
, vol.274
, pp. 259-262
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Lefebvre, O.1
Chenard, M.P.2
Masson, R.3
Linares, J.4
Dierich, A.5
LeMeur, M.6
Wendling, C.7
Tomasetto, C.8
Chambon, P.9
Rio, M.C.10
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14
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0029559314
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Regulation of lineage-specific transcription of the sucrase-isomaltase gene in transgenic mice and cell lines
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Markowitz AJ, Wu GD, Bader A, Cui Z, Chen L, Traber PG: Regulation of lineage-specific transcription of the sucrase-isomaltase gene in transgenic mice and cell lines. Am J Physiol 1995, 95(6 pt 1):G925-G939. Analysis of the sucrase-isomaltase gene promoter using transgenic mice demonstrates the lack of lineage specific regulatory elements in regions -8500 to +54 and suggests repression of transcription occurs in nonenterocytic cells.
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(1995)
Am J Physiol
, vol.95
, Issue.6 PART 1
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Markowitz, A.J.1
Wu, G.D.2
Bader, A.3
Cui, Z.4
Chen, L.5
Traber, P.G.6
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15
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0030062178
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Congenital sucrase-isomaltase deficiency: Identification of a glutamine to proline substitution that leads to a transport block of sucrase-isomaltase in a pre-Golgi compartment
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Ouwendijk J, Moolenaar CE, Peters WJ, Hollenberg CP, Ginsel LA, Fransen JA, Naim HY: Congenital sucrase-isomaltase deficiency: identification of a glutamine to proline substitution that leads to a transport block of sucrase-isomaltase in a pre-Golgi compartment. J Clin Invest 1996, 96:633-641. This study identifies a single base pair mutation in the sucrase-isomaltase gene of a patient with congenital sucrase-isomaltase deficiency responsible for incorrect protein transport and consequent lack of sucrase-isomaltase activity.
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(1996)
J Clin Invest
, vol.96
, pp. 633-641
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Ouwendijk, J.1
Moolenaar, C.E.2
Peters, W.J.3
Hollenberg, C.P.4
Ginsel, L.A.5
Fransen, J.A.6
Naim, H.Y.7
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16
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0028825119
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Human dipeptidyl peptidase IV gene promoter: Tissue-specific regulation from a TATA-less GC-rich sequence characteristic of a housekeeping gene promoter
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Bohm SK, Gum JR Jr, Erickson RH, Hicks JW, Kim YS: Human dipeptidyl peptidase IV gene promoter: tissue-specific regulation from a TATA-less GC-rich sequence characteristic of a housekeeping gene promoter. Biochem J 1995, 95(pt 3):835-843.
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(1995)
Biochem J
, vol.95
, Issue.3 PART
, pp. 835-843
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Bohm, S.K.1
Gum Jr., J.R.2
Erickson, R.H.3
Hicks, J.W.4
Kim, Y.S.5
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17
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0028178540
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Expression of multiple gamma-glutamyltransferase genes in man
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Courtay C, Heisterkamp N, Siest G, Groffen J: Expression of multiple gamma-glutamyltransferase genes in man. Biochem J 1994, 94(pt 3):503-508.
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(1994)
Biochem J
, vol.94
, Issue.3 PART
, pp. 503-508
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Courtay, C.1
Heisterkamp, N.2
Siest, G.3
Groffen, J.4
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18
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0030070154
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The epithelial mucin MUC1 contains at least two discrete signals specifying membrane localization in cells
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Pemberton LF, Rughetti A, Taylor-Papadimitriou J, Gendler SJ: The epithelial mucin MUC1 contains at least two discrete signals specifying membrane localization in cells. J Biol Chem 1996, 96:2332-2340. Mutational analysis demonstrating the involvement of two different motifs in apical localization of MUC-1.
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(1996)
J Biol Chem
, vol.96
, pp. 2332-2340
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Pemberton, L.F.1
Rughetti, A.2
Taylor-Papadimitriou, J.3
Gendler, S.J.4
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19
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0030046992
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Anchorage mediated by integrin alpha6beta4 to laminin 5 (epiligrin) regulates tyrosine phosphorylation of a membrane-associated 80-kD protein
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Xia Y, Gil SG, Carter WG: Anchorage mediated by integrin alpha6beta4 to laminin 5 (epiligrin) regulates tyrosine phosphorylation of a membrane-associated 80-kD protein. J Cell Biol 1996, 96:727-740. This study demonstrates that a single ligand, laminin 5, activates two different effector pathways via the a6β4 and α3β1 integrins.
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(1996)
J Cell Biol
, vol.96
, pp. 727-740
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Xia, Y.1
Gil, S.G.2
Carter, W.G.3
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