Role of nuclear factor-κB in atherogenesis

Experimental Physiology

Volumn 82, Issue 2, 1997, Pages 297-304

  Brand, Korbinian ^a   Page, Sharon ^a   Walli, Autar K ^b   Neumeier, Dieter ^a   Baeuerle, Patrick A ^c  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR;

ARTERY INTIMA; ARTERY MEDIA; ATHEROGENESIS; ATHEROSCLEROSIS; CELL PROLIFERATION; FIBROMUSCULAR DYSPLASIA; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; INFLAMMATION; MACROPHAGE; PATHOGENESIS; REVIEW; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

EID: 0030889302     PISSN: 09580670     EISSN: None     Source Type: Journal    
DOI: 10.1113/expphysiol.1997.sp004025     Document Type: Review

References (26)

1. ARES, M. P. S., KALLIN, B., ERIKSSON, P. & NILSSON, J. (1995). Oxidized LDL induces transcription factor activator protein-1 but inhibits activation of nuclear factor-κB in human vascular smooth muscle cells. Arteriosclerosis, Thrombosis and Vascular Biology 15, 1585-1590.
2. AUTIERI, M. V., YUE, T. L., FEUERSTEIN, G. Z. & OHLSTEIN, E. (1995). Antisense oligonucleotides to the p65 subunit of NF-κB inhibit human vascular smooth muscle cell adherence and proliferation and prevent neointima formation in rat carotid arteries. Biochemical and Biophysical Research Communications 213, 827-836.
3. BAEUERLE, P. A. & HENKEL, T. (1994). Function and activation of NF-κB in the immune system. Annual Review of Immunology 12, 141-179.
4. BALDWIN, A. S. JR (1996). The NF-κB and IκB proteins: New discoveries and insights. Annual Review of Immunology 14, 649-681.
5. BARATH, P., FISHBEIN, M. C., LAO, J., BERNSON, J., HELFAUT, R. H. & FORRESTER, J. S. (1990). Tumor necrosis factor gene expression in human vascular smooth muscle cells detected by in vitro hybridization. American Journal of Pathology 137, 503-509.
6. BELLAS, R. E., LEE, J. S. & SONENSHEIN, G. E. (1995). Expression of a constitutive NF-κB-like activity is essential for proliferation of cultured bovine vascular smooth muscle cells. Journal of Clinical Investigation 96, 2521-2527.
7. BERLINER, J. A., NAVAB, M., FOGELMAN, A. M., FRANK, J. S., DEMER, L. L., EDWARDS, P. A., WATSON, A. D. & LUSIS, A. J. (1995). Atherosclerosis: Basic mechanisms - oxidation, inflammation, and genetics. Circulation 91, 2488-2496.
8. BRAND, K., BANKA, C. L., MACKMAN, N., TERKELTAUB, R. A., FAN, S. T. & CURTISS, L. K. (1994). Oxidized low density lipoprotein enhances lipopolysaccharide-induced tissue factor expression in human adherent monocytes. Arteriosclerosis and Thrombosis 14, 790-797.
9. BRAND, K., FOWLER, B. J., EDGINGTON, T. S. & MACKMAN, N. (1991). Tissue factor mRNA in THP-1 monocytic cells is regulated at both transcriptional and post-transcriptional levels in response to lipopolysaccharide. Molecular and Cellular Biology 11, 4732-4738.
10. BRAND, K., MACKMAN, N. & CURTISS, L. K. (1993). Interferon-γ inhibits macrophage apolipoprotein E production by posttranslational mechanisms. Journal of Clinical Investigation 91, 2031-2039.
11. BRAND, K., PAGE, S., ROGLER, G., BARTSCH, A., BRANDL, R., KNUECHEL, R., PAGE, M., KALTSCHMIDT, C., BAEUERLE, P. A. & NEUMEIER, D. (1996). Activated transcription factor NF-kappa B is present in the atherosclerotic lesion. Journal of Clinical Investigation 97, 1715-1722.
12. COLLINS, T. (1993). Endothelial nuclear factor-κB and the initiation of the atherosclerotic lesion. Laboratory Investigation 68, 499-508.
13. CYBULSKY, M. I. & GIMBRONE, M. A. JR (1991). Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science 251, 788-791.
14. KALTSCHMIDT, C., KALTSCHMIDT, B., LANNES-VIEIRA, J., KREUTZBERG, G. W., WEKERLE, H., BAEUERLE, P. A. & GEHRMANN, J. (1994). Transcription factor NF-κB is activated in microglia during experimental autoimmune encephalomyelitis. Journal of Neuroimmunology 55, 99-106.
15. MACKMAN, N., BRAND, K. & EDGINGTON, T. S. (1991). Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor κB binding sites. Journal of Experimental Medicine 174, 1517-1526.
16. PARHAMI, F., FANG, Z. T., FOGELMAN, A. M., ANDALIBI, A., TERRITO, M. C. & BERLINER, J. A. (1993). Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate. Journal of Clinical Investigation 92, 471-478.
17. PENG, H. P., RAJAVASHISTH, T. B., LIBBY, P. & LIAO, J. K. (1995). Nitric oxide inhibits macrophage-colony stimulating factor gene transcription in vascular endothelial cells. Journal of Biological Chemistry 270, 17050-17055.
18. QWARNSTRÖM, E. E., OSTBERG, C. O., TURK, G. L., RICHARDSON, C. A. & BOMSZTYK, K. (1994). Fibronectin attachment activates the NF-κB p50/p65 heterodimer in fibroblasts and smooth muscle cells. Journal of Biological Chemistry 269, 30765-30768.
19. RAJAVASHISTH, T. B., YAMADA, H. & MISHRA, N. K. (1995). Transcriptional activation of the macrophage-colony stimulating factor gene by minimally modified LDL. Arteriosclerosis, Thrombosis and Vascular Biology 15, 1591-1598.
20. Ross, R. (1993). The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362, 801-809.
21. SHACKELFORD, R. E., MISRA, U. K., FLORINE-CASTEEL, K., THAI, S.-F., PIZZO, S. V. & ADAMS, D. O. (1995). Oxidized low density lipoprotein suppresses activation of NFκB in macrophages via a pertussis toxin-sensitive signaling mechanism. Journal of Biological Chemistry 270, 3475-3478.
22. TERKELTAUB, R., BANKA, C. L., SOLAN, J., SANTORO, D., BRAND, K. & CURTISS, L. K. (1994). Oxidized LDL induces monocytic cell expression of interleukin-8, a chemokine with T-lymphocyte chemotactic activity. Arteriosclerosis and Thrombosis 14, 47-53.
23. THANOS, D. & MANIATIS, T. (1995). NF-κB: A lesson in family values. Cell 80, 529-532.
24. WILCOX, J. N., SMITH, K. M., SCHWARTZ, S. M. & GORDON, D. (1989). Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque. Proceedings of the National Academy of Sciences of the USA 86, 2839-2843.
25. WITZTUM, J. L. & STEINBERG, D. (1991). Role of oxidized low density lipoprotein in atherogenesis. Journal of Clinical Investigation 88, 1785-1792.
26. YLÄ-HERTTUALA, S., LIPTON, B. A., ROSENFELD, M. E., SÄRKIOJA, T., YOSHIMURA, T., LEONARD, E. J., WITZTUM, J. L. & STEINBERG, D. (1991). Expression of monocyte chemoattractant protein-1 in macrophage-rich areas of human and rabbit atherosclerotic lesions. Proceedings of the National Academy of Sciences of the USA 88, 5252-5256.