-
1
-
-
0029041749
-
UK Medical Research Council randomised, multicentre trial of interferon-αn1 for chronic myeloid leukaemia: Improved survival irrespective of cytogenetic response
-
Allan, N.C., Richards, S.M. & Shepherd, P.C.A. (1995) UK Medical Research Council randomised, multicentre trial of interferon-αn1 for chronic myeloid leukaemia: improved survival irrespective of cytogenetic response. Lancet, 345, 1392-1397.
-
(1995)
Lancet
, vol.345
, pp. 1392-1397
-
-
Allan, N.C.1
Richards, S.M.2
Shepherd, P.C.A.3
-
2
-
-
0025032025
-
Bcr/abl recombinant DNA analysis versus karyotype in the diagnosis and therapeutic monitoring of chronic myeloid leukemia
-
Asycue, L.H., Ross, D.W., Ozer, H., Rao, K., Gulley, M.L. & Dent, G.A. (1990) Bcr/abl recombinant DNA analysis versus karyotype in the diagnosis and therapeutic monitoring of chronic myeloid leukemia. American Journal of Clinical Pathology, 94, 404-409.
-
(1990)
American Journal of Clinical Pathology
, vol.94
, pp. 404-409
-
-
Asycue, L.H.1
Ross, D.W.2
Ozer, H.3
Rao, K.4
Gulley, M.L.5
Dent, G.A.6
-
4
-
-
0023255851
-
T lymphocytes lack rearrangement of the bcr gene in Philadelphia chromosome-positive chronic myelocytic leukemia
-
Bartram, C.R., Raghavachar, A., Anger, B., Stain, C. & Bettelheim, P. (1987) T lymphocytes lack rearrangement of the bcr gene in Philadelphia chromosome-positive chronic myelocytic leukemia. Blood, 69, 1682-1685.
-
(1987)
Blood
, vol.69
, pp. 1682-1685
-
-
Bartram, C.R.1
Raghavachar, A.2
Anger, B.3
Stain, C.4
Bettelheim, P.5
-
5
-
-
0023615339
-
Utility of molecular genetic analysis of bcr rearrangement in the diagnosis of chronic myeloid leukemia
-
Benn, P., Soper, L., Eisenberg, A., Silver, R., Coleman, M., Cacciapaglia, B., Bennett, L., Baird, M., Silverstein, M., Berger, C. & Bernhardt, B. (1987) Utility of molecular genetic analysis of bcr rearrangement in the diagnosis of chronic myeloid leukemia. Cancer Genetics and Cytogenetics, 29, 1-7.
-
(1987)
Cancer Genetics and Cytogenetics
, vol.29
, pp. 1-7
-
-
Benn, P.1
Soper, L.2
Eisenberg, A.3
Silver, R.4
Coleman, M.5
Cacciapaglia, B.6
Bennett, L.7
Baird, M.8
Silverstein, M.9
Berger, C.10
Bernhardt, B.11
-
6
-
-
0023680713
-
Clinical evaluation of a DNA probe assay for the Philadelphia (Ph1) translocation in chronic myelogenous leukemia
-
Blennerhasset, G.T., Furth, M.E., Anderson, A., Burns, J.P., Chaganti, R.S.K., Blick, M., Talpaz, M., Dev, V.G., Chan, L.C., Wiedemann, L.M., Greaves, M.F., Hagemeijer, A., van der Plas, D., Skuse, G., Wang, N. & Stam, K. (1988) Clinical evaluation of a DNA probe assay for the Philadelphia (Ph1) translocation in chronic myelogenous leukemia. Leukemia, 2, 648-657.
-
(1988)
Leukemia
, vol.2
, pp. 648-657
-
-
Blennerhasset, G.T.1
Furth, M.E.2
Anderson, A.3
Burns, J.P.4
Chaganti, R.S.K.5
Blick, M.6
Talpaz, M.7
Dev, V.G.8
Chan, L.C.9
Wiedemann, L.M.10
Greaves, M.F.11
Hagemeijer, A.12
Van Der Plas, D.13
Skuse, G.14
Wang, N.15
Stam, K.16
-
7
-
-
0028153771
-
An optimized multiplex polymerase chain reaction (PCR) for detection of BCR-ABL fusion mRNAs in hematological disorders
-
Cross, N.C., Melo, J.V. Lin, F. & Goldman, J.M. (1994) An optimized multiplex polymerase chain reaction (PCR) for detection of BCR-ABL fusion mRNAs in hematological disorders. Leukemia, 8, 186-189.
-
(1994)
Leukemia
, vol.8
, pp. 186-189
-
-
Cross, N.C.1
Melo, J.V.2
Lin, F.3
Goldman, J.M.4
-
8
-
-
0020333906
-
A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia
-
de Klein, A., van Kessel, A.G., Grosveld, G., Bartram, C.R., Hagemeijer, A., Bootsma, D., Spurr, N.K., Heisterkamp, N., Groffen, J. & Stephenson, J.R. (1982) A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia. Nature, 300, 765-767.
-
(1982)
Nature
, vol.300
, pp. 765-767
-
-
De Klein, A.1
Van Kessel, A.G.2
Grosveld, G.3
Bartram, C.R.4
Hagemeijer, A.5
Bootsma, D.6
Spurr, N.K.7
Heisterkamp, N.8
Groffen, J.9
Stephenson, J.R.10
-
9
-
-
0024447857
-
Bcr rearrangement: Potential false positive secondary to an EcoRI restriction length polymorphism
-
Fishleder, A.J., Shadrach, B. & Tuttle, C. (1989) Bcr rearrangement: potential false positive secondary to an EcoRI restriction length polymorphism. Leukemia, 10, 746-748.
-
(1989)
Leukemia
, vol.10
, pp. 746-748
-
-
Fishleder, A.J.1
Shadrach, B.2
Tuttle, C.3
-
10
-
-
0028233960
-
T lymphocytes in chronic myelogenous leukemia (CML): No evidence of the BCR/ABL fusion gene detected by fluorescence in situ hybridization in 14 patients
-
Garicochea, B., Chase, A., Lazaridou, A. & Goldman, J.M. (1994) T lymphocytes in chronic myelogenous leukemia (CML): no evidence of the BCR/ABL fusion gene detected by fluorescence in situ hybridization in 14 patients. Leukemia, 8, 1197-1201.
-
(1994)
Leukemia
, vol.8
, pp. 1197-1201
-
-
Garicochea, B.1
Chase, A.2
Lazaridou, A.3
Goldman, J.M.4
-
11
-
-
0021346853
-
Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22
-
Groffen, J., Stephenson, J.R., Heisterkamp, N., de Klein, A., Bartram, C.R. & Grosveld, C. (1984) Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22. Cell, 36, 93-99.
-
(1984)
Cell
, vol.36
, pp. 93-99
-
-
Groffen, J.1
Stephenson, J.R.2
Heisterkamp, N.3
De Klein, A.4
Bartram, C.R.5
Grosveld, C.6
-
12
-
-
0025105067
-
Multiple restriction enzyme digests are required to rule out polymorphism in the molecular diagnosis of chronic myeloid leukemia
-
Grossman, A., Mathew, A., O'Connell, M.P., Tiso, P., Distenfeld, A. & Benn, P. (1990) Multiple restriction enzyme digests are required to rule out polymorphism in the molecular diagnosis of chronic myeloid leukemia. Leukemia, 4, 63-64.
-
(1990)
Leukemia
, vol.4
, pp. 63-64
-
-
Grossman, A.1
Mathew, A.2
O'Connell, M.P.3
Tiso, P.4
Distenfeld, A.5
Benn, P.6
-
13
-
-
0025827426
-
Densitometric analysis of Southern blot autoradiographs and its application to monitoring patients with chronic myeloid leukemia
-
Grossman, A., Silver, R., Szatrowski, T., Gutfriend, A., Verma, R. & Benn, P. (1991) Densitometric analysis of Southern blot autoradiographs and its application to monitoring patients with chronic myeloid leukemia. Leukemia, 5, 540-547.
-
(1991)
Leukemia
, vol.5
, pp. 540-547
-
-
Grossman, A.1
Silver, R.2
Szatrowski, T.3
Gutfriend, A.4
Verma, R.5
Benn, P.6
-
14
-
-
1842298964
-
BCR-ABL protein expression in peripheral blood cells of chronic myelogenous leukemia patients undergoing therapy
-
Guo, J.Q., Lian, J.Y., Xian, Y.M., Lee, M.S., Deisseroth, A.B., Stass, S.A., Champlin, R.E., Talpaz, M., Wang, Y.J. & Arlinghaus, R.B. (1994) BCR-ABL protein expression in peripheral blood cells of chronic myelogenous leukemia patients undergoing therapy. Blood, 83, 3629-3637.
-
(1994)
Blood
, vol.83
, pp. 3629-3637
-
-
Guo, J.Q.1
Lian, J.Y.2
Xian, Y.M.3
Lee, M.S.4
Deisseroth, A.B.5
Stass, S.A.6
Champlin, R.E.7
Talpaz, M.8
Wang, Y.J.9
Arlinghaus, R.B.10
-
15
-
-
0028170517
-
Randomized comparison of interferon-alpha with busulfan and hydroxyurea in chronic myelogenous leukemia (CML)
-
Hehlmann, R., Heimpel, H., Hasford, J., Kolb, H.J., Pralle, H., Hossfeld, D.K., Queißer, W., Löffler, H., Hochhaus, A., Heinze, B., Georgii, A., Bartram, C.R., Grießhammer, M., Bergmann, L., Essers, U., Falge, C., Queisser, U., Meyer, P., Schmitz, N., Eimermacher, H., Walther, F., Fett, W., Kleeberg, U.R., Käbisch, A., Nerl, C., Zimmermann, R., Meuret, G., Tichelli, A., Kann, L., Tigges, F.J., Schmid, L., Brockhaus, W., Tobler, A., Reiter, A., Perker, M., Emmerich, B., Verpoort, K., Zankovich, R., von Wussow, P., Prümmer, O., Thiele, J., Buhr, T., Carbonell, F., Ansari, H., and the German CML Study Group (1994) Randomized comparison of interferon-alpha with busulfan and hydroxyurea in chronic myelogenous leukemia (CML). Blood, 84, 4064-4077.
-
(1994)
Blood
, vol.84
, pp. 4064-4077
-
-
Hehlmann, R.1
Heimpel, H.2
Hasford, J.3
Kolb, H.J.4
Pralle, H.5
Hossfeld, D.K.6
Queißer, W.7
Löffler, H.8
Hochhaus, A.9
Heinze, B.10
Georgii, A.11
Bartram, C.R.12
Grießhammer, M.13
Bergmann, L.14
Essers, U.15
Falge, C.16
Queisser, U.17
Meyer, P.18
Schmitz, N.19
Eimermacher, H.20
Walther, F.21
Fett, W.22
Kleeberg, U.R.23
Käbisch, A.24
Nerl, C.25
Zimmermann, R.26
Meuret, G.27
Tichelli, A.28
Kann, L.29
Tigges, F.J.30
Schmid, L.31
Brockhaus, W.32
Tobler, A.33
Reiter, A.34
Perker, M.35
Emmerich, B.36
Verpoort, K.37
Zankovich, R.38
Von Wussow, P.39
Prümmer, O.40
Thiele, J.41
Buhr, T.42
Carbonell, F.43
Ansari, H.44
more..
-
16
-
-
13344250478
-
Quantification of residual disease in chronic myelogenous leukemia patients on interferon-α therapy by competitive polymerase chain reaction
-
Hochhaus, A., Lin, F., Reiter, A., Skladny, H., Mason, P.J., van Rhee, F., Shepherd, P.C.A., Allan, N.C., Hehlmann, R., Goldman, J.M. & Cross, N.C.P. (1996a) Quantification of residual disease in chronic myelogenous leukemia patients on interferon-α therapy by competitive polymerase chain reaction. Blood, 87, 1549-1555.
-
(1996)
Blood
, vol.87
, pp. 1549-1555
-
-
Hochhaus, A.1
Lin, F.2
Reiter, A.3
Skladny, H.4
Mason, P.J.5
Van Rhee, F.6
Shepherd, P.C.A.7
Allan, N.C.8
Hehlmann, R.9
Goldman, J.M.10
Cross, N.C.P.11
-
17
-
-
0029133984
-
Variable numbers of BCR-ABL transcripts persist in CML patients who achieve complete cytogenetic remission with interferon-α
-
Hochhaus, A., Lin, F., Reiter, A., Skladny, H., van Rhee, F. Shepherd, P.C.A., Allan, N.C. Hehlmann, R., Goldman, J.M. & Cross, N.C.P. (1995) Variable numbers of BCR-ABL transcripts persist in CML patients who achieve complete cytogenetic remission with interferon-α. British Journal of Haematology, 91, 126-131.
-
(1995)
British Journal of Haematology
, vol.91
, pp. 126-131
-
-
Hochhaus, A.1
Lin, F.2
Reiter, A.3
Skladny, H.4
Van Rhee, F.5
Shepherd, P.C.A.6
Allan, N.C.7
Hehlmann, R.8
Goldman, J.M.9
Cross, N.C.P.10
-
18
-
-
9544227358
-
A novel BCR-ABL fusion gene (e6a2) in a patient with Philadelphia chromosome negative chronic myelogenous leukemia
-
Hochhaus, A., Reiter, A., Skladny, H., Melo, J.V., Sick, C., Berger, U., Guo, J.Q., Arlinghaus, R.B., Hehlmann, R., Goldman, J.M. & Cross, N.C.P. (1996b) A novel BCR-ABL fusion gene (e6a2) in a patient with Philadelphia chromosome negative chronic myelogenous leukemia. Blood, 88, 2236-2240.
-
(1996)
Blood
, vol.88
, pp. 2236-2240
-
-
Hochhaus, A.1
Reiter, A.2
Skladny, H.3
Melo, J.V.4
Sick, C.5
Berger, U.6
Guo, J.Q.7
Arlinghaus, R.B.8
Hehlmann, R.9
Goldman, J.M.10
Cross, N.C.P.11
-
19
-
-
0028813711
-
Prolonged survival in chronic myelogenous leukemia after cytogenetic response to interferon-α therapy
-
Kantarjian, H.M., Smith, T.L., O'Brien, S., Beran, M., Pierce, S. & Talpaz, M. (1995) Prolonged survival in chronic myelogenous leukemia after cytogenetic response to interferon-α therapy. Annals of Internal Medicine, 122, 254-261.
-
(1995)
Annals of Internal Medicine
, vol.122
, pp. 254-261
-
-
Kantarjian, H.M.1
Smith, T.L.2
O'Brien, S.3
Beran, M.4
Pierce, S.5
Talpaz, M.6
-
20
-
-
0023730047
-
Restriction fragment length polymorphism of bcr in Japanese patients with hematological malignancies
-
Kato, Y., Sawada, H., Tashima, M., Yumoto, Y., Okuda, T., Ueda, T., Uchino, H., Hotta, T., Mitutani, S., Ono, T. & Ogawa, K. (1988) Restriction fragment length polymorphism of bcr in Japanese patients with hematological malignancies. Leukemia, 2, 701-703.
-
(1988)
Leukemia
, vol.2
, pp. 701-703
-
-
Kato, Y.1
Sawada, H.2
Tashima, M.3
Yumoto, Y.4
Okuda, T.5
Ueda, T.6
Uchino, H.7
Hotta, T.8
Mitutani, S.9
Ono, T.10
Ogawa, K.11
-
21
-
-
0023753576
-
The molecular genetics of Philadelphia chromosome-positive leukemias
-
Kurzrock, R., Gutterman, J.U. & Talpaz, M. (1988) The molecular genetics of Philadelphia chromosome-positive leukemias. New England Journal of Medicine, 319, 990-998.
-
(1988)
New England Journal of Medicine
, vol.319
, pp. 990-998
-
-
Kurzrock, R.1
Gutterman, J.U.2
Talpaz, M.3
-
22
-
-
0028181636
-
BCR-ABL chronic myeloid leukemia: The missing link with chronic myelomonocytic leukemia?
-
BCR-ABL chronic myeloid leukemia: the missing link with chronic myelomonocytic leukemia? Leukemia, 8, 208-211.
-
(1994)
Leukemia
, vol.8
, pp. 208-211
-
-
Melo, J.V.1
Myint, H.2
Galton, D.A.G.3
Goldman, J.M.4
-
23
-
-
0026068188
-
Minimal residual disease in patients with chronic myelogenous leukemia undergoing long-term treatment with recombinant interferon-α2b alone or in combination with interferon γ
-
Opalka, B., Wandlm U.B., Becher, R., Kloke, O., Nagel-Hiemke, M., Moritz, T., Beer, U., Seeber, S., Niederle, N. (1991) Minimal residual disease in patients with chronic myelogenous leukemia undergoing long-term treatment with recombinant interferon-α2b alone or in combination with interferon γ. Blood, 78, 2188-2193.
-
(1991)
Blood
, vol.78
, pp. 2188-2193
-
-
Opalka, B.1
Wandlm, U.B.2
Becher, R.3
Kloke, O.4
Nagel-Hiemke, M.5
Moritz, T.6
Beer, U.7
Seeber, S.8
Niederle, N.9
-
24
-
-
0027361154
-
Prolonged subcutaneous administration of recombinant α2b interferon in patients with previously untreated Philadelphia chromosome-positive chronic-phase chronic myelogenous leukemia: Effect on remission duration and survival: Cancer and Leukemia Group B study 8583
-
Ozer, H., George, S.L., Schiffer, C.A., Rao, K., Rao, P.N., Wurster-Hill, D.H., Arthur, D.D., Powell, B., Gottlieb, A., Peterson, B.A., Rai, K., Testa, J.R., Le Beau, M., Tantravahi, R. & Bloomfield, C.D. (1993) Prolonged subcutaneous administration of recombinant α2b interferon in patients with previously untreated Philadelphia chromosome-positive chronic-phase chronic myelogenous leukemia: effect on remission duration and survival: Cancer and Leukemia Group B study 8583. Blood, 82, 2975-2984.
-
(1993)
Blood
, vol.82
, pp. 2975-2984
-
-
Ozer, H.1
George, S.L.2
Schiffer, C.A.3
Rao, K.4
Rao, P.N.5
Wurster-Hill, D.H.6
Arthur, D.D.7
Powell, B.8
Gottlieb, A.9
Peterson, B.A.10
Rai, K.11
Testa, J.R.12
Le Beau, M.13
Tantravahi, R.14
Bloomfield, C.D.15
-
26
-
-
4244149421
-
Molecular monitoring of bcr/abl fusion gene in chronic myelogenous leukemia: Peripheral blood analysis is comparable to a bone marrrow examination
-
Stock, W., Westbrook, C., Peterson, B., Szatrowski, T., Silver, R., Schiffer, C. & Bloomfield, C. (1993) Molecular monitoring of bcr/abl fusion gene in chronic myelogenous leukemia: peripheral blood analysis is comparable to a bone marrrow examination. Blood, 82, 331a.
-
(1993)
Blood
, vol.82
-
-
Stock, W.1
Westbrook, C.2
Peterson, B.3
Szatrowski, T.4
Silver, R.5
Schiffer, C.6
Bloomfield, C.7
-
27
-
-
0025854383
-
Interferon-alpha produces sustained cytogenetic responses in chronic myelogenous leukemia: Philadelphia chromosome-positive patients
-
Talpaz, M., Kantarjian, H.M., Kurzrock, R., Trujillo, J.M. & Gutterman, J.U. (1991) Interferon-alpha produces sustained cytogenetic responses in chronic myelogenous leukemia: Philadelphia chromosome-positive patients. Annals of Internal Medicine, 114, 532-538.
-
(1991)
Annals of Internal Medicine
, vol.114
, pp. 532-538
-
-
Talpaz, M.1
Kantarjian, H.M.2
Kurzrock, R.3
Trujillo, J.M.4
Gutterman, J.U.5
-
28
-
-
23444462074
-
Interferon alfa-2a as compared with convential chemotherapy for the treatment of chronic myeloid leukemia
-
The Italian Cooperative Study Group on Chronic Myeloid Leukemia (1994) Interferon alfa-2a as compared with convential chemotherapy for the treatment of chronic myeloid leukemia. New England Journal of Medicine, 330, 820-825.
-
(1994)
New England Journal of Medicine
, vol.330
, pp. 820-825
-
-
-
29
-
-
0029944705
-
The majority of T-lymphocytes are polyclonal during the chronic phase of chronic myelogenous leukemia
-
Tsukamoto, N., Karasawa, M., Maehara, T., Okamoto, K., Sakai, H., Naruse, T., Morita, K., Tsuchiya, J. & Omine, M. (1996) The majority of T-lymphocytes are polyclonal during the chronic phase of chronic myelogenous leukemia. Annals of Haematology, 72, 61-65.
-
(1996)
Annals of Haematology
, vol.72
, pp. 61-65
-
-
Tsukamoto, N.1
Karasawa, M.2
Maehara, T.3
Okamoto, K.4
Sakai, H.5
Naruse, T.6
Morita, K.7
Tsuchiya, J.8
Omine, M.9
-
30
-
-
0029005051
-
Quantification of the breakpoint cluster region rearrangement for clinical monitoring in Philadelphia chromosome-positive chronic myeloid leukemia
-
Verschraegen, C.F., Talpaz, M., Hirsch-Ginsberg, C.F., Pherwani, R., Rios, M.B., Stass, S.A. & Kantarjian, H.M. (1995) Quantification of the breakpoint cluster region rearrangement for clinical monitoring in Philadelphia chromosome-positive chronic myeloid leukemia. Blood, 85, 2705-2710.
-
(1995)
Blood
, vol.85
, pp. 2705-2710
-
-
Verschraegen, C.F.1
Talpaz, M.2
Hirsch-Ginsberg, C.F.3
Pherwani, R.4
Rios, M.B.5
Stass, S.A.6
Kantarjian, H.M.7
-
31
-
-
0027474736
-
Detection of residual proliferating leukemic cells by fluorescence in situ hybridization in CML patients in complete remission after interferon treatment
-
Zhao L., Kantarjian, H.M., van Oort, J., Cork, A., Trujilio, J.M. & Liang, J.C. (1993) Detection of residual proliferating leukemic cells by fluorescence in situ hybridization in CML patients in complete remission after interferon treatment. Leukemia, 7, 168-174.
-
(1993)
Leukemia
, vol.7
, pp. 168-174
-
-
Zhao, L.1
Kantarjian, H.M.2
Van Oort, J.3
Cork, A.4
Trujilio, J.M.5
Liang, J.C.6
|