Intracerebral microdialysis study of glutamate reuptake in awake, behaving rats

Brain Research

Volumn 766, Issue 1-2, 1997, Pages 1-10

  Alexander, Guillermo M ^a   Grothusen, John R ^a   Gordon, Sharon W ^a   Schwartzman, Robert J ^a  

^a Broad Vine MS 423 Allegheny U ^*  (United States)

Author keywords

Awake; Frontoparietal cortex; Glutamate reuptake; Microdialysis; Phenylephrine; Rat

Indexed keywords

3 HYDROXYASPARTIC ACID; ALPHA ADRENERGIC RECEPTOR; AMINO ACID RECEPTOR AFFECTING AGENT; GLUTAMIC ACID; PHENTOLAMINE; PHENYLEPHRINE;

AMINO ACID METABOLISM; AMINO ACID TRANSPORT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; FRONTAL CORTEX; MALE; MICRODIALYSIS; NERVE CELL; NONHUMAN; PARIETAL LOBE; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; WAKEFULNESS;

3,4-DIHYDROXYPHENYLACETIC ACID; ANIMALS; ANTI-BACTERIAL AGENTS; ASPARTIC ACID; BEHAVIOR, ANIMAL; CARBON RADIOISOTOPES; CONSCIOUSNESS; FRONTAL LOBE; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; GLUTAMINE; HOMOVANILLIC ACID; HYDROXYINDOLEACETIC ACID; MALE; MANNITOL; MICRODIALYSIS; NOREPINEPHRINE; PARIETAL LOBE; PHENTOLAMINE; PHENYLEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; SYMPATHOLYTICS; SYMPATHOMIMETICS; SYNAPTIC TRANSMISSION; TRITIUM;

EID: 0030886112     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00519-2     Document Type: Article

References (55)

1. Arriza J.L., Fairman W.A., Wadiche J.I., Murdoch G.H., Kavanaugh M.P., Amara S.G. Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J. Neurosci. 14:1994;5559-5569.
2. +-dependent high affinity uptake of L-glutamate in primary cultures of human fibroblasts isolated from three different types of tissue. FEBS Lett. 339:1994;50-54.
3. Begley D.J., Reichel A., Ermisch A. Simple high-performance liquid chromatographic analysis of free primary amino acid concentrations in rat plasma and cisternal cerebrospinal fluid. J. Chromatogr. B - Biomed. Appl. 657:1994;185-191.
4. Bruhn T., Christensen T., Diemer N.H. Microdialysis as a tool for in vivo investigation of glutamate transport capacity in rat brain. J. Neurosci. Methods. 59:1995;169-174.
5. Bungay P.M., Morrison P.F., Dedrick R.L. Steady-state theory for quantitative microdialysis of solutes and water in vivo and in vitro. Life Sci. 46:1990;105-119.
6. Crone C. The permeability of capillaries in various organs as determined by use of the 'indicator diffusion' method. Acta Physiol. Scand. 58:1963;292-305.
7. Dalley J.W., Stanford S.C. Incremental changes in extracellular noradrenaline availability in the frontal cortex induced by naturalistic environmental stimuli: a microdialysis study in the freely moving rat. J. Neurochem. 65:1995;2644-2651.
8. Derouiche A. Possible role of the Müller cell in uptake and metabolism of glutamate in the mammalian outer retina. Vision Res. 36:1996;3875-3878.
9. Donzanti B.A., Yamamoto B.K. An improved and rapid HPLC-EC method for the isocratic separation of amino acid neurotransmitters from brain tissue and microdialysis perfusates. Life Sci. 43:1988;913-922.
10. Dugan L.L., Bruno V.M.G., Amagasu S.M., Giffard R.G. Glia modulate the response of murine cortical neurons to excitotoxicity: glia exacerbate AMPA neurotoxicity. J. Neurosci. 15:1995;4545-4555.
11. Fahrig T. Receptor subtype involved and mechanism of norepinephrine-induced stimulation of glutamate uptake into primary cultures of rat brain astrocytes. Glia. 7:1993;212-218.
12. Fairman W.A., Vandenberg R.J., Arriza J.L., Kavanaugh M.P., Amara S.G. An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature. 375:1995;599-603.
13. Fonnum F. Glutamate: a neurotransmitter in mammalian brain. J. Neurochem. 42:1984;1-11.
14. 3H]glutamate transport in glial cultures. J. Neurochem. 64:1995;2572-2580.
15. Gundersen V., Danbolt N.C., Ottersen O.P., Storm-Mathisen J. Demonstration of glutamate/aspartate uptake activity in nerve endings by use of antibodies recognizing exogenous D-aspartate. Neuroscience. 57:1993;97-111.
16. Hansson E., Ronnback L. Regulation of glutamate and GABA transport by adrenoceptors in primary astroglial cell cultures. Life Sci. 44:1989;27-34.
17. Hansson E., Ronnback L. Receptor regulation of the glutamate, GABA and taurine high-affinity uptake into astrocytes in primary culture. Brain Res. 548:1991;215-221.
18. Hansson E., Ronnback L. Adrenergic receptor regulation of amino acid neurotransmitter uptake in astrocytes. Brain Res. Bull. 29:1992;297-301.
19. Hansson E., Ronnback L. Astrocytes in glutamate neurotransmission. FASEB J. 9:1995;343-350.
20. Herrera-Marschitz M., You Z.-B., Goiny M., Meana J.J., Silveira R., Godukhin O.V., Chen Y., Espinoza S., Pettersson E., Loidl C.F., Lubec G., Andersson K., Nylander I., Terenius L., Ungerstedt U. On the origin of extracellular glutamate levels monitored in the basal ganglia of the rat by in vivo microdialysis. J. Neurochem. 66:1996;1726-1735.
21. Hertz L. Autonomic control of neuronal-astrocytic interactions, regulating metabolic activities, and ion fluxes in the CNS. Brain Res. Bull. 29:1992;303-313.
22. 3H]dopamine and dopamine-antagonists on cultured astrocytes of rat striatum and spinal cord: an autoradiographic study. Neurosci. Lett. 65:1986;177-182.
23. Hosli E., Hosli L. Receptors for neurotransmitters on astrocytes in the mammalian central nervous system. Prog. Neurobiol. 40:1993;477-506.
24. Jacobson I., Sandberg M., Hamberger A. Mass transfer in brain dialysis devices - a new method for the estimation of extracellular amino acids concentration. J. Neurosci. Methods. 15:1985;263-268.
25. Justice J.B. Jr. Quantitative microdialysis of neurotransmitters. J. Neurosci. Methods. 48:1993;263-276.
26. Kanai Y., Bhide P.G., Difiglia M., Hediger M.A. Neuronal high-affinity glutamate transport in the rat central nervous system. NeuroReport. 6:1995;2357-2362.
27. Kanai Y., Hediger M.A. Primary structure and functional characterization of a high-affinity glutamate transporter. Nature. 360:1992;467-471.
28. Kanai Y., Smith C.P., Hediger M.A. A new family of neurotransmitter transporters: the high-affinity glutamate transporters. FASEB J. 8:1994;1450-1459.
29. Kehr J. A survey on quantitative microdialysis: theoretical models and practical implications. J. Neurosci. Methods. 48:1993;251-261.
30. Kerkerian L., Dusticier N., Nieoullon A. Modulatory effect of dopamine on high-affinity glutamate uptake in the rat striatum. J. Neurochem. 48:1987;1301-1306.
31. Meldrum B., Garthwaite J. Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmacol. Sci. 11:1990;379-387.
32. Miele M., Berners M., Boutelle M.G., Kusakabe H., Fillenz M. The determination of the extracellular concentration of brain glutamate using quantitative microdialysis. Brain Res. 707:1996;131-133.
33. Mori F., Cuadra G., Giacobini E. Metrifonate effects on acetylcholine and biogenic amines in rat cortex. Neurochem. Res. 20:1995;1081-1088.
34. Morrison P.F., Bungay P.M., Hsiao J.K., Ball B.A., Mefford I.N., Dedrick R.L. Quantitative microdialysis: analysis of transients and application to pharmacokinetics in brain. J. Neurochem. 57:1991;103-119.
35. 3H]D-aspartate in the rat striatum in-vitro. J. Pharm. Pharmacol. 40:1988;307-308.
36. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, Academic Press, New York, 1986.
37. Peng L., Hertz L., Huang R., Sonnewald U., Petersen S.B., Westergaard N., Larsson O., Schousboe A. Utilization of glutamine and of TCA cycle constituents as precursors for transmitter glutamate and GABA. Dev. Neurosci. 15:1993;367-377.
38. Pines G., Danbolt N.C., Bjoras M., Zhang Y., Bendahan A., Eide L., Koepsell H., Storm-Mathisen J., Seeberg E., Kanner B.I. Cloning and expression of a rat brain L-glutamate transporter. Nature. 360:1992;464-467.
39. Rocher C., Bert L., Robert F., Trouvin J.H., Renaud B., Jacquot C., Gardier A.M. Microdialysis monitoring of variations in extracellular levels of serotonin, GABA and excitatory amino acids in the frontal cortex of awake rats in response to a single peripheral or central administration of dexfenfluramine. Brain Res. 737:1996;221-230.
40. Rollema H., Alexander G.M., Grothusen J.R., Matos F.F., Castagnoli N. Jr. Comparison of the effects of intracerebrally administered MPP+ (1-methyl-4-phenylpyridinium) in three species: microdialysis of dopamine and metabolites in mouse, rat and monkey striatum. Neurosci. Lett. 106:1989;275-281.
41. Rothstein J.D., Martin L., Levey A.I., Dykes-Hoberg M., Jin L., Wu D., Nash N., Kuncl R.W. Localization of neuronal and glial glutamate transporters. Neuron. 13:1994;713-725.
42. Rothstein J.D., Martin L.J., Kuncl R.W. Decreased glutamate transport by brain and spinal cord in amyotrophic lateral sclerosis. N. Engl. J. Med. 326:1992;1464-1468.
43. Rothstein J.D., Van Kammen M., Levey A.I., Martin L.J., Kuncl R.W. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann. Neurol. 38:1995;73-84.
44. Schousboe A. Transport and metabolism of glutamate and GABA in neurons and glial cells. Int. Rev. Neurobiol. 22:1981;1-45.
45. Sharp T., Maidment N.T., Brazell M.P., Zetterstrom T., Ungerstedt U., Bennett G.W., Marsden C.A. Changes in monoamine metabolites measured by simultaneous in vivo differential pulse voltammetry and intracerebral dialysis. Neuroscience. 12:1984;1213-1221.
46. Smith A.D., Justice J.B. The effect of inhibition of synthesis, release, metabolism and uptake on the microdialysis extraction fraction of dopamine. J. Neurosci. Methods. 54:1994;75-82.
47. +-dependent glutamate/aspartate transporter from rat brain. Proc. Natl. Acad. Sci. USA. 89:1992;10955-10959.
48. Summers K.L., Giacobini E. Effects of local and repeated systemic administration of (-)nicotine on extracellular levels of acetylcholine, norepinephrine, dopamine, and serotonin in rat cortex. Neurochem. Res. 20:1995;753-759.
49. Swanson R.A., Miller J.W., Rothstein J.D., Farrell K., Stein B.A., Longuemare M.C. Neuronal regulation of glutamate transporter subtype expression in astrocytes. J. Neurosci. 17:1997;932-940.
50. Tsumoto T. Excitatory amino acid transmitters and their receptors in neural circuits of the cerebral neocortex. Neurosci. Res. 9:1990;79-102.
51. Velaz-Faircloth M., McGraw T.S., Malandro M.S., Fremeau R.T. Jr., Kilberg M.S., Anderson K.J. Characterization and distribution of the neuronal glutamate transporter EAAC1 in rat brain. Am. J. Physiol. Cell Physiol. 270:1996;C67-C75.
52. Volterra A., Bezzi P., Rizzini B.L., Trotti D., Ullensvang K., Danbolt N.C., Racagni G. The competitive transport inhibitor L-trans-pyrrolidine-2,4-dicarboxylate triggers excitotoxicity in rat cortical neuron-astrocyte co-cultures via glutamate release rather than uptake inhibition. Eur. J. Neurosci. 8:1996;2019-2028.
53. Westerink B.H.C. Brain microdialysis and its application for the study of animal behaviour. Behav. Brain Res. 70:1995;103-124.
54. Zetterstrom T., Sharp T., Marsden C.A., Ungerstedt U. In vivo measurement of dopamine and its metabolites by intracerebral dialysis: changes after D-amphetamine. J. Neurochem. 41:1983;1769-1773.
55. Zhu X., Giacobini E., Hornsperger J.-M. Effect of MDL 73,745 on acetylcholine and biogenic amine levels in rat cortex. Eur. J. Pharmacol. 276:1995;93-99.