Taxol induces apoptosis in human colon carcinoma cell lines arrested in G2/M phase

Oncology Reports

Volumn 4, Issue 6, 1997, Pages 1151-1156

  Tatebe, Shigeru ^a   Osaki, Mitsuhiko ^a   Goto, Akira ^a   Ito, Hisao ^a  

^a TOTTORI UNIVERSITY   (Japan)

Author keywords

Apoptosis; Bcl 2; Human colon carcinoma cells; Taxol

Indexed keywords

GENISTEIN; PACLITAXEL; PROTEIN BCL 2; PROTEIN TYROSINE KINASE INHIBITOR;

APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL CYCLE G2 PHASE; COLON CARCINOMA; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; METAPHASE; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0030884976     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: 10.3892/or.4.6.1151     Document Type: Article

References (39)

1. Wani MC, Taylor HL, Wall ME, et al: The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. J Am Chem Soc 93: 2325-2327, 1971.
2. Straubinger RM, Sharma A, Murray M and Mayhew E: Novel taxol formations: taxol-containing liposomes. J Natl Cancer Inst Monogr 15: 69-78, 1993.
3. Liebmann JE, Cook JA, Lipschultz C, Teague D, Fisher J and Mitchell JB: Cytotoxic studies of paclitaxel (taxol) in human tumour cell lines. Br J Cancer 68: 1104-1109, 1993.
4. Manfredi JJ and Horwitz SB: Taxol: an antimitotic agent with a new mechanism of action. Pharmacol Ther 25: 83-125, 1984.
5. Horwitz SB: Mechanism of action of taxol. Trends Pharmacol Sci 13: 134-136, 1992.
6. Donaldson KL, Goolsby GL and Wahl AF: Cytotoxicity of the anticancer agents cisplatin and taxol during cell proliferation and the cell cycle. Int J Cancer 57: 847-855, 1994.
7. Bhalla K, Ibrado AM, Tourkina E, Tang C, Mahoney ME and Huang Y: Taxol induces internucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cells. Leukemia 4: 563-568, 1993.
8. Chang YF, Li LL, Wu CW, Liu TY, Lui WY, P'eng FK and Chi CW: Paclitaxel-induced apoptosis in human gastric carcinoma cell lines. Cancer 77: 14-18, 1996.
9. Nishio K, Arioka H, Ishida T, Fukumoto H, Kurokawa H, Sata M, Ohata M and Saijo N: Enhanced interaction between tubulin and microtubule-associated protein 2 via inhibition of MAP kinase and cdc2 kinase by paclitaxel. Int J Cancer 63: 688-693, 1995.
10. Liu Y, Bhalla K, Hill C and Priest DG: Evidence for involvement of tyrosine phosphorylation in taxol-induced apoptosis in a human ovarian tumor cell line. Biochem Pharmacol 48: 1265-1272, 1994.
11. cdc2 coincident with taxol-induced apoptosis. Cell Growth Differ 5: 1041-1050, 1994.
12. Tang C, Willingham MC, Reed JC, Miyashita T, Ray S, Ponnathpur V, Huang Y, Mahoney ME, Bullock G and Bhalla K: High levels of p26BCL-2 oncoprotein retard taxol-induced apoptosis in human pre-B leukemia cells. Leukemia 8: 1960-1969, 1994.
13. Zhan Q, Fan S, Bae I, Guillouf C, Liebermann DA, O'Connor PM, et al: Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis. Oncogene 9: 3743-3751, 1994.
14. Lowe SW, Schmitt EM, Smith SW, Osborne BA and Jacks T: p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847-849, 1993.
15. Tone S, Tanaka S and Kato K: The cell-cycle and cell-population kinetics on the programmed cell death in the limb-buds of normal and 5-bromo deoxyuridine-trcated chick embryos. Dev Growth Differ 30: 261-270, 1988.
16. 1 arrest and apoptosis. Cancer Res 54: 1169-1174, 1994.
17. Miyashita T, Krajewski S, Krajewska M, Wang HG, Lin HK, Liebermann DA, Hoffman B and Reed JC: Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 9: 1799-1805, 1994.
18. Miyashita T and Reed JC: Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80: 293-299, 1995.
19. 2/M transitions of the cell cycle: identification of major phosphorylation sites. EMBO J 10: 305-316, 1991.
20. Ohsumi K, Katagiri C and Kishimoto T: Chromosome condensation in Xenopus mitotic extracts without histone H1. Science 262: 2033-2035, 1993.
21. cdc2 kinase to microtubules and is a potential regulator of M-phase microtubule dynamics. J Cell Biol 128: 849-862, 1995.
22. cdc2 activation required for apoptosis. Science 263: 1143-1145, 1994.
23. Shimizu T, O'Conner PM, Kohn KW and Pommier Y: Unscheduled activation of cyclin B1/cdc2 kinase in human promyelocytic leukemia cell line HL60 cells undergoing apoptosis induced by DNA damage. Cancer Res 55: 228-231, 1995.
24. Quinn LA, Moore GE, Morgan RT and Woods LK: Cell lines from human colon carcinoma with unusual cell products, double minutes, and homogeneously staining regions. Cancer Res 39: 4914-4929, 1979.
25. Tibbetts LM, Chu MY, Hager JC, Dexter DL and Calabresi P: Chemotherapy of cell-line-derived human colon carcinomas in mice immunosuppressed with antithymocyte serum. Cancer 40: 2651-2659, 1977.
26. Drewinko B, Romsdahl MM, Tang LY, Ahearn MJ and Trujillo JM: Establishment of a human carcinoembryonic antigen-producing colon adenocarcinoma cell line. Cancer Res 36: 467-475, 1976.
27. S sensitizes MCF-7 cells to chemotherapy-induced apoptosis. Cancer Res 55: 2507-2510, 1995.
28. Gorczyca W, Gong J, Ardelt B, Traganous F and Darzynkiewicz Z: The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. Cancer Res 53: 3186-3192, 1993.
29. Pickard M, Dive C and Kinsella AR: Differences in resistance to 5-fluorouracil as a function of cell cycle delay and not apoptosis. Br J Cancer 72: 1389-1396, 1995.
30. Willingham MC and Bhalla K: Transient mitotic phase localization of bcl-2 oncoprotein in human carcinoma cells and its possible role in prevention of apoptosis. J Histochem Cytochem 42: 441-450, 1994.
31. Vaux D, Cory S and Adams J: Bcl-2 gene promotes hematopoietic cell survival and co-operates with c-myc to immortalize pre-B-cells. Nature 335: 440-442, 1988.
32. Alnemri ES, Fernandez TF, Haldar S, Croce CM and Litwack G: Involvement of bcl-2 in glucocorticoid-induced apoptosis of human pre B-leukemias. Cancer Res 52: 491-495, 1992.
33. Sentman CL, Slatter JR, Hockenberry D, Kanagawa O and Korsmeyer SJ: Bcl-2 inhibits multiple form of apoptosis but not negative selection in thymocytes. Cell 67: 879-888, 1992.
34. Kamesaki S, Kamesaki H, Jorgensen TJ, Tanizawa A, Pommier Y and Cossman J: bcl-2 protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair. Cancer Res 53: 4251-4256, 1993.
35. Miyashita T and Reed JC: bcl-2 gene transfer increases relative resistance of S49.1 and EHI17.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs. Cancer Res 52: 5407-5411, 1992.
36. Lacronique V, Mignon A, Fabre M, Viollet B, Rouquet N, Molina T, Porteu A, Henrion A, Bouscary D, Varlet P, Joulin V and Kahn A: Bcl-2 protects from lethal hepatic apoptosis induced by an anti-Fas antibody in mice. Nature Med 2: 80-86, 1996.
37. Haldar S, Jena N and Croce CM: Antiapoptosis potential of bcl-2 oncogene by dephosphorylation. Biochem Cell Biol 72: 455-462, 1994.
38. Haldar S, Jena N and Croce CM: Inactivation of Bcl-2 by phosphorylation. Proc Natl Acad Sci USA 92: 4507-4511, 1995.
39. Haldar S, Chintapalli J and Croce CM: Taxol induces bcl-2 phosphorylation and death of prostate cancer cells. Cancer Res 56: 1253-1255, 1996.