Peroxisomal localization of α-oxidation in human liver

Journal of Inherited Metabolic Disease

Volumn 20, Issue 5, 1997, Pages 665-673

  Casteels, M ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; ADENOSINE TRIPHOSPHATE; ASCORBIC ACID; COENZYME A; MAGNESIUM ION;

ARTICLE; CELLULAR DISTRIBUTION; FATTY ACID OXIDATION; HUMAN; HUMAN TISSUE; LIVER HOMOGENATE; LIVER METABOLISM; PEROXISOME;

HUMANS; LIVER; MICROBODIES; OXIDATION-REDUCTION;

EID: 0030882145     PISSN: 01418955     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005370325260     Document Type: Article

References (12)

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2. Casteels M, Croes K, Van Veldhoven PP, Mannaerts GP (1996) α-Oxidation of 3-methyl-substituted fatty acids in liver of rat and man. Formation of a 2-OH-3-methylacyl-CoA intermediate. J Inher Metab Dis 19 (supplement 1): 81 (abstract).
3. Croes K, Casteels M, Van Veldhoven PP, Mannaerts GP (1995) Evidence for the importance of iron in the α-oxidation of 3-methyl-substituted fatty acids in the intact cell. Biochim Biophys Acta 1255: 63-67.
4. 2, cofactor requirements, subcellular localization and formation of a 2-hydroxy-3-methylacyl-CoA intermediate. Eur J Biochem 240: 674-683.
5. Declercq PE, Haagsman HP, Van Veldhoven PP, Debeer LJ, Van Golde LMG, Mannaerts GP (1984) Rat liver dihydroxyacetone-phosphate acyltransferases and their contribution to glycerolipid synthesis. J Biol Chem 259: 9064-9075.
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7. Jakobs BS, van den Bogert C, Dacremont G, Wanders RJA (1994) β-Oxidation of fatty acids in cultured human skin fibroblasts devoid of the capacity for oxidative phosphorylation. Biochim Biophys Acta 1211: 37-43.
8. Jansen GA, Wanders RJA, de Groot CJ, Moser HW, Mihalik SJ, Watkins PAJ (1996) Phytanoyl-CoA hydroxylase deficiency: discovery of the long-sought enzyme defect in Refsum disease. J Inher Metab Dis 19 (supplement 1): 5 (abstract).
9. Mihalik SJ, Rainville AM, Watkins PA (1995) Phytanic acid α-oxidation in rat liver peroxisomes. Production of α-hydroxyphytanoyl-CoA and formate is enhanced by dioxygenase cofactors. Eur J Biochem 232: 545-551.
10. Pahan K, Khan M, Singh I (1996) Phytanic acid oxidation:normal activation and transport yet defective α-hydroxylation of phytanic acid in peroxisomes from Refsum disease and rhizomelic chondrodysplasia punctata. J Lipid Res 37: 1137-1143.
11. Pahan K, Singh I (1993) Intraorganellar localization of CoASH-independent phytanic acid oxidation in human liver peroxisomes. FEBS Lett 333: 154-158.
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