Inhibition of DNA topoisomerase II by azaelliptitoxins functionalized in the variable substituent domain

Journal of Medicinal Chemistry

Volumn 39, Issue 11, 1996, Pages 2188-2196

  Tepe, Jetze J ^a   Madalengoitia, Jose S ^a   Slunt, Kelli M ^a   Werbovetz, Karl W ^a   Spoors, P Grant ^a   Macdonald, Timothy L ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

11 (4 CYANOANILINO)AZATOXIN; AZATOXIN; GYRASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG CONFORMATION; DRUG DNA BINDING; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME ACTIVITY; INHIBITION KINETICS; STRUCTURE ACTIVITY RELATION;

ANILINE COMPOUNDS; DNA; DNA TOPOISOMERASES, TYPE II; ENZYME INHIBITORS; HUMANS; INDICATORS AND REAGENTS; INDOLES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030008968     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9508806     Document Type: Article

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