Dopaminergic modulation of sodium current in hippocampal neurons via cAMP-dependent phosphorylation of specific sites in the sodium channel α subunit

Journal of Neuroscience

Volumn 17, Issue 19, 1997, Pages 7330-7338

  Cantrell, Angela R ^a   Smith, Raymond D ^b   Goldin, Alan L ^b   Scheuer, Todd ^a   Catterall, William A ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CAMP dependent protein kinase; Dopamine receptors; Hippocampus; Na+ current; Neuromodulation; Phosphorylation

Indexed keywords

2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 5,6 DICHLOROBENZIMIDAZOLE RIBOSIDE; 6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DOPAMINE 1 RECEPTOR STIMULATING AGENT; PHOSPHOROTHIOIC ACID DERIVATIVE; SODIUM CHANNEL; SODIUM ION;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; HIPPOCAMPUS; MALE; NERVE CELL EXCITABILITY; NEUROMODULATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SODIUM CURRENT; VOLTAGE CLAMP;

EID: 0030880487     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-19-07330.1997     Document Type: Article

References (41)

1. Arnt J, Hyttel J, Sánchcz C (1992) Partial and full dopamine D1 receptor agonists in mice and rats: relation between behavioral effects and stimulation of adenylate cyclase activity in vitro. Eur J Pharmacol 213:259-267.
2. 2+ currents in acutely-isolated, adult rat neostriatal neurons. J Neurosci 14:6667-6686.
3. 2+ activated potassium conductance in mammalian hippocampal pyramidal cells. Nature 297:76-79.
4. Berretta N, Berton F, Bianchi R, Capogna M, Francesconi W, Brunelli M (1990) Effects of dopamine, D-l and D-2 dopaminergic agonists on the excitability of hippocampal CA1 pyramidal cells in guinea pig. Exp Brain Res 83:124-130.
5. Biscoc TJ, Straughan DW (1966) Microiontophorctic studies of neurones in the cat hippocampus. J Physiol (Lond) 183:341-359.
6. Brussaard AB, Lodder JC, Maat AT, De Vliegcr TA, Kits KS (1991) Inhibitory modulation by FMRFamide of the voltage-gated sodium current in identified neurons in Lymnaea stagnalis. J Physiol (Lond) 441:385-404.
7. Cantrell AR, Ma JY, Scheuer T, Catterall WA (1996a) Muscarinic modulation of sodium current by activation of protein kinase C in rat hippocampal neurons. Neuron 16:1019-1026.
8. Cantrcll AR, Scheuer T, Catterall WA (1996h) Dopamine modulates sodium current via PKA activation in rat hippocampal neurons. Soc Neurosci Abstr 22:57.
9. + current by activation of Dl-like dopamine receptors is potentiated by depolarization and activation of protein kinase C. Soc Neurosci Abstr, in press.
10. Cheng HC, Kemp BE, Pearson RB, Smith AJ, Misconi L, VanPatten SM, Walsh DA (1986) A potent inhibitor of the cAMP-dependent protein kinase. J Biol Chem 261:989-992.
11. Civelli O, Bunzow JR, Grandy DK (1993) Molecular diversity of the dopamine receptors. Annu Rev Pharmacol Toxicol 32:281-307.
12. Costa MR, Catterall WA (1984) Cyclic AMP-dependent phosphorylation of the α subunit of the sodium channel in synaptic nerve ending particles. J Biol Chem 259:8210-8218.
13. Costa MR, Casnellie JE, Catterall WA (1982) Selective phosphorylation of the α subunit of the sodium channel by cAMP-dependcnt protein kinase. J Biol Chem 257:7918-7921.
14. + current in Xenopus oocytes. J Neurosci 12:3743-3752.
15. Hamill OP, Marty A, Neher E, Sakman B, Sigworth EC (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 391:85-100.
16. Hass HL, Konnerth A (1983) Histamine and noradrenaline decrease calcium-activated potassium conductance in hippocampal pyramidal cells. Nature 302:432-434.
17. Herrling PL (1981) The membrane potential of cat hippocampal neurons recorded in vivo displays four different reaction mechanisms to iontophoretically applied transmitter agonists. Brain Res 212:331-343.
18. House C, Kemp BE (1987) Protein kinase C contains a pseudosubstrate prototype in its regulatory subunit. Science 238:1726-1728.
19. Howe AR, Surmeier DJ (1995) Muscarinic receptors modulate N-, P-, and L-type calcium currents in rat striatal neurons through parallel pathways. J Neurosci 15:458-469.
20. Jurman ME, Boland LM, Liu Y, Yellen G (1994) Visual identification of individual transfected cells for electrophysiological recording. Biotechniques 17:876-881.
21. Li M, West JW, Lai Y, Scheuer T, Catterall WA (1992) Functional modulation of brain sodium channels by cAMP-dependent phosphorylation. Neuron 8:1151-1159.
22. Li M, West JW, Numann R, Murphy BJ, Scheuer T, Catterall WA (1993) Convergent regulation of sodium channels by protein kinasc C and cAMP-dependent protein kinase. Science 261:1439-1442.
23. Malenka RC, Nicoll RA (1986) Dopamine decreases the calcium-activated afterhyperpolarization in hippocampal CA1 pyramidal neurons. Brain Res 379:210-215.
24. Margolskee RF, McHendry-Rinde B, Horn R (1993) Panning transfected cells for electrophysiological studies. Biotechniques 15:906-911.
25. Meador-Woodruff JH, Grandy DK, Van Tol HHM, Damask SP, Little KY, Civelli O, Watson SJ (1994) Dopamine receptor gene expression in the human medial temporal lobe. Neuropsychopharmacology 10:239-248.
26. Murphy BJ, Rossie S, De Jongh KS, Catterall WA (1993) Identification of the sites of selective phosphorylation and dephosphorylation of the rat brain sodium channel α subunit by cAMP-dependent protein kinase and phosphoprotein phosphatases. J Biol Chem 268:27355-27362.
27. O'Dowd BF (1993) Structures of dopamine receptors. J Neurochem 60:804-816.
28. Pockett S (1985) Dopamine changes the shape of action potentials in hippocampal pyramidal cells. Brain Res 342:386-390.
29. Rossie S, Catterall WA (1987) Cyclic AMP-dependent phosphorylation of voltage-sensitive sodium channels in primary cultures of rat brain neurons. J Biol Chem 262:12735-12744.
30. Rossie S, Catterall WA (1989) Phosphorylation of the α subunit of rat brain sodium channels by cAMP-dependent protein kinase at a new site containing Ser686 and Ser687. J Biol Chem 264:14220-14224.
31. Rossie S, Gordon D, Catterall WA (1987) Identification of an intracellular domain of the sodium channel having multiple cAMP-dependent phosphorylation sites. J Biol Chem 262:17530-17535.
32. Sandberg M, Butt E, Nolte C, Fischer L, Halbrugge M, Beltman J, Jahnsen T, Genieser HG, Jastorff B, Walter U (1991) Characterization of Sp-5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole-3′,5′- monophosphorothioate (Sp-5,6-DC1-cBiMPS) as a potent and specific activator of cyclic-AMP-dependent protein kinase in cell extracts and intact cells. Biochem J 279:521-527.
33. Schiffmann SN, Lledo PM, Vincent JD (1995) Dopamine D1 receptor modulates the voltage-gated sodium current in rat striatal neurones through a protein kinase A. J Physiol (Lond) 483.1:95-107.
34. Sibley DR, Monsma FJ (1992) Molecular biology of dopamine receptors. Trends Pharmacol Sci 13:61-75.
35. Smith RD, Goldin AL (1996) Phosphorylation of brain sodium channels in the I-II linker modulates channel function in Xenopus oocytes. J Neurosci 16:1965-1974.
36. Smith RD, Goldin AL (1997) Phosphorylation at a single site in the brain sodium channel is necessary and sufficient for current reduction by protein kinase A. J Neurosci 17:6086-6093.
37. Stanzione P, Calabresi P, Mercuri N, Bernardi G (1984) Dopamine modulates CA1 hippocampal neurons by elevating the threshold for spike generation: an in vitro study. J Neurosci 13:1105-1116.
38. Stoof JC, Kebabian JW (1981) Opposing roles for D1 and D2 dopamine receptors in the efflux of cyclic AMP from rat neostriatum. Nature 294:366-368.
39. Stoof JC, Kebabian JW (1984) Two dopamine receptors: biochemistry, physiology and pharmacology. Life Sci 35:2281-2296.
40. Surmeier DJ, Eberwine J, Wilson CJ, Stefani A, Kitai ST (1992) Dopamine receptor subtypes co-localize in rat striatonigral neurons. Proc Natl Acad Sci USA 89:10178-10182.
41. Tukey JW (1977) Exploratory data analysis. Menlo Park, CA: Addison-Wesley.