-
1
-
-
0031048319
-
Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: Design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity
-
Kim, C.U., et al., & Stevens, R.C. (1997). Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity. J. Am. Chem. Soc. 119, 681-690.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 681-690
-
-
Kim, C.U.1
Stevens, R.C.2
-
2
-
-
0020633096
-
Structure of the catalytic and antigenic sites in influenza virus neuraminidase
-
Colman, P.M., Varghese, J.N. & Laver, W.G. (1983). Structure of the catalytic and antigenic sites in influenza virus neuraminidase. Nature 303, 41-44.
-
(1983)
Nature
, vol.303
, pp. 41-44
-
-
Colman, P.M.1
Varghese, J.N.2
Laver, W.G.3
-
3
-
-
0030050255
-
Neuraminidase inhibitors as potential anti-influenza drugs
-
Bamford, M.J. (1995). Neuraminidase inhibitors as potential anti-influenza drugs. J. Enzyme Inhibition 10, 1-16.
-
(1995)
J. Enzyme Inhibition
, vol.10
, pp. 1-16
-
-
Bamford, M.J.1
-
4
-
-
0028113435
-
Influenza virus neuraminidase: Structure, antibodies, and inhibitors
-
Colman, P.M. (1994). Influenza virus neuraminidase: structure, antibodies, and inhibitors. Protein Sci. 3, 1687-1696.
-
(1994)
Protein Sci.
, vol.3
, pp. 1687-1696
-
-
Colman, P.M.1
-
5
-
-
0028813628
-
Influenza type A virus neuraminidase does not play a role in viral entry, replication, assembly, or budding
-
Liu, C., Eichelberger, M.C., Compans, R.W. & Air, G.M. (1995). Influenza type A virus neuraminidase does not play a role in viral entry, replication, assembly, or budding. J. Virol. 69, 1099-1006.
-
(1995)
J. Virol.
, vol.69
, pp. 1099-11006
-
-
Liu, C.1
Eichelberger, M.C.2
Compans, R.W.3
Air, G.M.4
-
6
-
-
0013936514
-
The inhibition of neuraminidase and antiviral action
-
Edmond, J.D., Johnstone, R.G., Kidd, D., Rylance, H.J. & Sommerville, R.G. (1966). The inhibition of neuraminidase and antiviral action. Br. J. Pharmacol. Chemother. 27, 415-426.
-
(1966)
Br. J. Pharmacol. Chemother.
, vol.27
, pp. 415-426
-
-
Edmond, J.D.1
Johnstone, R.G.2
Kidd, D.3
Rylance, H.J.4
Sommerville, R.G.5
-
7
-
-
84945736084
-
2-Deoxy-2,3-dehydrosialic acids II. Competitive inhibition of Vibrio cholerae neuraminidase by 2-deoxy-2,3, dehydroneuraminic acids
-
Meindl, P. & Tuppy, H. (1969). 2-Deoxy-2,3-dehydrosialic acids II. Competitive inhibition of Vibrio cholerae neuraminidase by 2-deoxy-2,3, dehydroneuraminic acids. Hoppe-Seyler's Z. Physiol. Chem. 350, 1088-1092.
-
(1969)
Hoppe-Seyler's Z. Physiol. Chem.
, vol.350
, pp. 1088-1092
-
-
Meindl, P.1
Tuppy, H.2
-
8
-
-
0015959249
-
Inhibition of neuraminidase activity by derivatives of 2-deoxy-2,3-dehydro-N-acetylneuraminic acid
-
Meindl, P., Bodo, G., Palese, P., Schulman, J. & Tuppy, H. (1974). Inhibition of neuraminidase activity by derivatives of 2-deoxy-2,3-dehydro-N-acetylneuraminic acid. Virology 58, 457-463.
-
(1974)
Virology
, vol.58
, pp. 457-463
-
-
Meindl, P.1
Bodo, G.2
Palese, P.3
Schulman, J.4
Tuppy, H.5
-
9
-
-
0020629047
-
Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 Å resolution
-
Varghese, J.N., Laver, W.G. & Colman, P.M. (1983). Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 Å resolution. Nature 303, 35-40.
-
(1983)
Nature
, vol.303
, pp. 35-40
-
-
Varghese, J.N.1
Laver, W.G.2
Colman, P.M.3
-
10
-
-
0027287506
-
Rational design of potent sialidase-based inhibitors of influenza virus replication
-
von Itzstein, M., et al., & Penn, C.R. (1993). Rational design of potent sialidase-based inhibitors of influenza virus replication. Nature 363, 418-423.
-
(1993)
Nature
, vol.363
, pp. 418-423
-
-
Von Itzstein, M.1
Penn, C.R.2
-
11
-
-
0030044141
-
A study of the active site of influenza virus sialidase: An approach to the rational design of novel anti-influenza drugs
-
von Itzstein, M., et al., & Pegg, M.S. (1996). A study of the active site of influenza virus sialidase: an approach to the rational design of novel anti-influenza drugs. J. Med. Chem. 39, 388-391.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 388-391
-
-
Von Itzstein, M.1
Pegg, M.S.2
-
12
-
-
0021871375
-
A computational procedure for determining energetically favorable binding sites on biologically important macromolecules
-
Goodford, P.J. (1985). A computational procedure for determining energetically favorable binding sites on biologically important macromolecules. J. Med. Chem. 28, 849-857.
-
(1985)
J. Med. Chem.
, vol.28
, pp. 849-857
-
-
Goodford, P.J.1
-
13
-
-
0027510004
-
Further development of hydrogen-bond functions for use in determining energetically favourable binding sites on molecules of known structure. 2. Ligand probe groups with the ability to form more than two hydrogen bonds
-
Wade, R.C. & Goodford, P.J. (1993). Further development of hydrogen-bond functions for use in determining energetically favourable binding sites on molecules of known structure. 2. Ligand probe groups with the ability to form more than two hydrogen bonds. J. Med. Chem. 36, 148-156.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 148-156
-
-
Wade, R.C.1
Goodford, P.J.2
-
14
-
-
0030296267
-
Mutation in the influenza virus neuraminidase gene resulting in decreased sensitivity to the neuraminidase inhibitor 4-guanidino-Neu5Ac2en leads to instability of the enzyme
-
McKimm-Breschkin, J.L., McDonald, M., Blick, T.J. & Colman, P.M. (1996). Mutation in the influenza virus neuraminidase gene resulting in decreased sensitivity to the neuraminidase inhibitor 4-guanidino-Neu5Ac2en leads to instability of the enzyme. Virology 225, 240-242.
-
(1996)
Virology
, vol.225
, pp. 240-242
-
-
McKimm-Breschkin, J.L.1
McDonald, M.2
Blick, T.J.3
Colman, P.M.4
-
15
-
-
0029003145
-
Three-dimensional structure of the complex of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase
-
Varghese, J.N., Epa, V.C. & Colman, P.M. (1995). Three-dimensional structure of the complex of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase. Protein Sci. 4, 1081-1087.
-
(1995)
Protein Sci.
, vol.4
, pp. 1081-1087
-
-
Varghese, J.N.1
Epa, V.C.2
Colman, P.M.3
-
16
-
-
0028325249
-
Molecular modeling studies on ligand binding to sialidase from influenza virus and the mechanism of catalysis
-
Taylor, N.R. & von Itzstein, M. (1994). Molecular modeling studies on ligand binding to sialidase from influenza virus and the mechanism of catalysis. J. Med. Chem. 37, 616-624.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 616-624
-
-
Taylor, N.R.1
Von Itzstein, M.2
-
17
-
-
0030157593
-
A structural and energetics analysis of the binding of a series of N-acetylneuraminic-acid-based inhibitors to influenza virus sialidase
-
Taylor, N.R. & von Itzstein, M. (1996). A structural and energetics analysis of the binding of a series of N-acetylneuraminic-acid-based inhibitors to influenza virus sialidase. J. Comput Aided Mol. Des. 10, 233-246.
-
(1996)
J. Comput Aided Mol. Des.
, vol.10
, pp. 233-246
-
-
Taylor, N.R.1
Von Itzstein, M.2
-
18
-
-
0028925854
-
A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies
-
White, C.L., et al., & Luo, M. (1995). A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies. J. Mol. Biol. 245, 623-634.
-
(1995)
J. Mol. Biol.
, vol.245
, pp. 623-634
-
-
White, C.L.1
Luo, M.2
-
19
-
-
0028940702
-
Structures of aromatic inhibitors of influenza virus neuraminidase
-
Jedrzejas, M.J., et al., & Luo, M. (1995). Structures of aromatic inhibitors of influenza virus neuraminidase. Biochemistry 34, 3144-3151.
-
(1995)
Biochemistry
, vol.34
, pp. 3144-3151
-
-
Jedrzejas, M.J.1
Luo, M.2
-
20
-
-
0029099621
-
Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction
-
Singh, S., et al., & Brouillette, W.J. (1995). Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction. J. Med. Chem. 38, 3217-3225.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 3217-3225
-
-
Singh, S.1
Brouillette, W.J.2
-
21
-
-
0028805201
-
A strategy for theoretical binding constant, Ki, calculations for neuraminidase aromatic inhibitors designed on the basis of the active site structure of influenza virus neuraminidase
-
Jedrzejas, M.J., Singh, S., Brouillette, W.J., Air, G.M. & Luo, M. (1995). A strategy for theoretical binding constant, Ki, calculations for neuraminidase aromatic inhibitors designed on the basis of the active site structure of influenza virus neuraminidase. Proteins 23, 264-277.
-
(1995)
Proteins
, vol.23
, pp. 264-277
-
-
Jedrzejas, M.J.1
Singh, S.2
Brouillette, W.J.3
Air, G.M.4
Luo, M.5
-
22
-
-
0031552380
-
Guanidinobenzoic acid inhibitors of influenza virus neuraminidase
-
Sudbeck, E.A., et al., & Luo, M. (1997). Guanidinobenzoic acid inhibitors of influenza virus neuraminidase. J. Mol. Biol. 267, 584-594.
-
(1997)
J. Mol. Biol.
, vol.267
, pp. 584-594
-
-
Sudbeck, E.A.1
Luo, M.2
-
23
-
-
5444248415
-
Synthesis of a carbocyclic analogue of N-acetylneuraminic acid (pseudo-N-acetylneuraminic acid)
-
Ogawa, S., Yoshikawa, M. & Taki, T. (1992). Synthesis of a carbocyclic analogue of N-acetylneuraminic acid (pseudo-N-acetylneuraminic acid). J. Chem. Soc. Chem. Commun., 406-408.
-
(1992)
J. Chem. Soc. Chem. Commun.
, pp. 406-408
-
-
Ogawa, S.1
Yoshikawa, M.2
Taki, T.3
-
24
-
-
0019890491
-
Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution
-
Wilson, I.A., Skehel, J.J. & Wiley, D.C. (1981). Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution. Nature 289, 366-373.
-
(1981)
Nature
, vol.289
, pp. 366-373
-
-
Wilson, I.A.1
Skehel, J.J.2
Wiley, D.C.3
-
25
-
-
0027523625
-
Inhibition of the fusion-inducing conformational change of influenza hemagglutinin by benzoquinones and hydroquinones
-
Bodian, D.L., et al., & Kuntz, I.D. (1993). Inhibition of the fusion-inducing conformational change of influenza hemagglutinin by benzoquinones and hydroquinones. Biochemistry 32, 2967-2978.
-
(1993)
Biochemistry
, vol.32
, pp. 2967-2978
-
-
Bodian, D.L.1
Kuntz, I.D.2
-
26
-
-
12644259779
-
An approach to the design of anti-influenza agents
-
(Laver, W.G. & Air, G.M., eds), Academic Press, San Diego, USA
-
Wade, R.C. (1990). An approach to the design of anti-influenza agents. In Use of X-ray Crystallography in the Design of Antiviral Agents. (Laver, W.G. & Air, G.M., eds), pp. 61-74, Academic Press, San Diego, USA.
-
(1990)
Use of X-ray Crystallography in the Design of Antiviral Agents
, pp. 61-74
-
-
Wade, R.C.1
-
27
-
-
0026570977
-
CLIX: A search algorithm for finding novel ligands capable of binding proteins of known three-dimensional structure
-
Lawrence, M.C. & Davis, P.C. (1992). CLIX: a search algorithm for finding novel ligands capable of binding proteins of known three-dimensional structure. Proteins 12, 31-41.
-
(1992)
Proteins
, vol.12
, pp. 31-41
-
-
Lawrence, M.C.1
Davis, P.C.2
-
28
-
-
0028282687
-
HOOK: A program for finding novel molecular architectures that satisfy the chemical and steric requirements of a macromolecule binding site
-
Eisen, M.B., Wiley, D.C., Karplus, M. & Hubbard, R.E. (1994). HOOK: a program for finding novel molecular architectures that satisfy the chemical and steric requirements of a macromolecule binding site. Proteins 19, 199-221.
-
(1994)
Proteins
, vol.19
, pp. 199-221
-
-
Eisen, M.B.1
Wiley, D.C.2
Karplus, M.3
Hubbard, R.E.4
-
29
-
-
0026665418
-
The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor
-
Varghese, J.N., McKimm-Breschkin, J.L., Caldwell, J.B., Kortt, A.A. & Colman, P.M. (1992). The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor. Proteins 14, 327-332.
-
(1992)
Proteins
, vol.14
, pp. 327-332
-
-
Varghese, J.N.1
McKimm-Breschkin, J.L.2
Caldwell, J.B.3
Kortt, A.A.4
Colman, P.M.5
-
30
-
-
0027930960
-
Structure of influenza virus neuraminidase B/Lee/40 complexed with sialic acid and a dehydro analog at 1.8-Å resolution: Implications for the catalytic mechanism
-
Janakiraman, M.N., White, C.L., Laver, W.G., Air, G.M. & Luo, M. (1994). Structure of influenza virus neuraminidase B/Lee/40 complexed with sialic acid and a dehydro analog at 1.8-Å resolution: implications for the catalytic mechanism. Biochemistry 33, 8172-8179.
-
(1994)
Biochemistry
, vol.33
, pp. 8172-8179
-
-
Janakiraman, M.N.1
White, C.L.2
Laver, W.G.3
Air, G.M.4
Luo, M.5
-
31
-
-
0026508847
-
The 2.2 Å resolution crystal structure of influenza B neuraminidase and its complex with sialic acid
-
Burmeister, W.P., Ruigrok, R.W. & Cusack, S. (1992). The 2.2 Å resolution crystal structure of influenza B neuraminidase and its complex with sialic acid. EMBO J. 11, 49-56.
-
(1992)
EMBO J.
, vol.11
, pp. 49-56
-
-
Burmeister, W.P.1
Ruigrok, R.W.2
Cusack, S.3
-
32
-
-
0023915219
-
Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid
-
Weis, W., et al., & Wiley, D.C. (1988). Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid. Nature 333, 426-431.
-
(1988)
Nature
, vol.333
, pp. 426-431
-
-
Weis, W.1
Wiley, D.C.2
-
33
-
-
0026799307
-
Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: Analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography
-
Sauter, N.K., et al., & Wiley, D.C. (1992). Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography. Biochemistry 31, 9609-9621.
-
(1992)
Biochemistry
, vol.31
, pp. 9609-9621
-
-
Sauter, N.K.1
Wiley, D.C.2
-
34
-
-
0026515091
-
Use of sialic acid analogues to define functional groups involved in binding to the influenza virus hemagglutinin
-
Kelm, S., et al., & Zbiral, E. (1992). Use of sialic acid analogues to define functional groups involved in binding to the influenza virus hemagglutinin. Eur. J. Biochem. 205, 147-153.
-
(1992)
Eur. J. Biochem.
, vol.205
, pp. 147-153
-
-
Kelm, S.1
Zbiral, E.2
-
35
-
-
0000016640
-
Design and evaluation of a tightly binding fluorescent ligand for influenza A hemagglutinin
-
Weinhold, E.G. & Knowles, J.R. (1992). Design and evaluation of a tightly binding fluorescent ligand for influenza A hemagglutinin. J. Am. Chem. Soc. 114, 9270-9275.
-
(1992)
J. Am. Chem. Soc.
, vol.114
, pp. 9270-9275
-
-
Weinhold, E.G.1
Knowles, J.R.2
-
36
-
-
0028774043
-
Crystal structures of influenza virus hemagglutinin in complex with high-affinity receptor analogs
-
Watowich, S.J., Skehel, J.J. & Wiley, D.C. (1994). Crystal structures of influenza virus hemagglutinin in complex with high-affinity receptor analogs. Structure 2, 719-731.
-
(1994)
Structure
, vol.2
, pp. 719-731
-
-
Watowich, S.J.1
Skehel, J.J.2
Wiley, D.C.3
-
37
-
-
0028805760
-
Effective inhibitors of haemagglutination by influenza virus synthesized from polymers having active ester groups. Insight into mechanism of inhibition
-
Mammen, M., Dahmann, G. & Whitesides, G.M. (1995). Effective inhibitors of haemagglutination by influenza virus synthesized from polymers having active ester groups. Insight into mechanism of inhibition. J. Med. Chem. 38, 4179-4190.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 4179-4190
-
-
Mammen, M.1
Dahmann, G.2
Whitesides, G.M.3
-
38
-
-
0030250628
-
Optically controlled collisions of biological objects to evaluate potent polyvalent inhibitors of virus-cell adhesion
-
Mammen, M., Helmerson, K., Kishore, R., Choi, S.K., Phillips, W.D. & Whitesides, G.M. (1996). Optically controlled collisions of biological objects to evaluate potent polyvalent inhibitors of virus-cell adhesion. Chem. Biol. 3, 757-763.
-
(1996)
Chem. Biol.
, vol.3
, pp. 757-763
-
-
Mammen, M.1
Helmerson, K.2
Kishore, R.3
Choi, S.K.4
Phillips, W.D.5
Whitesides, G.M.6
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