Metastatic lesions from prostate cancer do not express oestrogen and progesterone receptors

Journal of Pathology

Volumn 182, Issue 3, 1997, Pages 356-361

  Hobisch, Alfred ^a   Hittmair, Anton ^b   Daxenbichler, Günter ^b   Wille, Stefan ^a   Radmayr, Christian ^a   Hobisch Hagen, Petra ^b   Bartsch, Georg ^a   Klocker, Helmut ^a   Culig, Zoran ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Androgen receptor; Cell lines; Endocrine therapy; Metastatic specimens; Oestrogen receptor; Progesterone receptor; Prostatic carcinoma; Tumour progression

Indexed keywords

ANDROGEN RECEPTOR; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIGAND BINDING; MALE; METASTASIS; PRIORITY JOURNAL; PROSTATE CARCINOMA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BONE NEOPLASMS; CASE-CONTROL STUDIES; EPIDURAL NEOPLASMS; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; MALE; POLYMERASE CHAIN REACTION; PROSTATIC NEOPLASMS; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; SOFT TISSUE NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0030875693     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199707)182:3<356::AID-PATH863>3.0.CO;2-U     Document Type: Article

References (39)

1. Ekman P, Barrack ER, Greene GL, Jensen EV, Walsh PC. Estrogen receptors in human prostate: evidence for multiple binding sites. J Clin Endocrinol Metab 1983; 54: 166-176.
2. Wolf RM, Schneider SL, Edson Pontes J, et al. Estrogen and progestin receptors in human prostatic carcinoma. Cancer 1985; 55: 2477-2481.
3. Brolin J, Ekman P. Microassays for androgen and progesterone receptor quantitation as compared with standard saturation analyses in human prostatic tissues. Urol Res 1991; 19: 333-336.
4. Green S, Walter P, Kumar V, et al. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature 1986; 320: 134-139.
5. Misrahi M, Atger M, d'Auriol L, et al. Complete amino acid sequence of the human progesterone receptor deduced from cloned cDNA. Biochem Biophys Res Commun 1987; 143: 740-748.
6. West NB, Roselli CE, Resko JA, Greene GL, Brenner RM. Estrogen and progestin receptors and aromatase activity in rhesus monkey prostate. Endocrinology 1988; 123: 2312-2322.
7. Brenner RM, West NB, McClellan MC. Estrogen and progestin receptors in the reproductive tract of male and female primates. Biol Reprod 1990; 42: 11-19.
8. Wernert N, Gerdes J, Loy V, Seitz G, Scherr O, Dhom G. Investigations of the estrogen (ER-ICA-test) and the progesterone receptor in the prostate and prostatic carcinoma on immunohistochemical basis. Virchows Arch A [Pathol Anat Histopathol] 1987; 412: 387-391.
9. Schulze H, Claus S. Histological localization of estrogen receptors in normal and diseased human prostates by immunocytochemistry. Prostate 1990; 16: 331-343.
10. Mobbs BG, Liu Y. Immunohistochemical localization of progesterone receptor in benign and malignant human prostate. Prostate 1990; 16: 245-251.
11. Berns EMJJ, de Boer W, Mulder E. Androgen-dependent growth regulation of and release of specific protein(s) by the androgen receptor containing human prostate tumor cell line LNCaP. Prostate 1986; 9: 247-259.
12. Sonnenschein C, Olea N, Pasanen ME, Soto AM. Negative controls of cell proliferation: human prostate and cancer cells and androgens. Cancer Res 1989; 49: 3474-3481.
13. Brolin J, Skoog L, Ekman P. Immunohistochemistry and biochemistry in detection of androgen, progesterone, and estrogen receptors in benign and malignant human prostatic tissue. Prostate 1992; 20: 281-295.
14. Veldscholte J, Ris-Stalpers CA, Kuiper GGJM, et al. A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens. Biochem Biophys Res Commun 1990; 173: 534-540.
15. Castagnetta LA, Miceli MD, Sorci CMG, et al. Growth of LNCaP human prostate cancer cells is stimulated by estradiol via its own receptor. Endocrinology 1995; 136: 2309-2319.
16. Carruba G, Pfeffer U, Fecarotta E, et al. Estradiol inhibits growth of hormone non-responsive PC3 human prostate cancer cells. Cancer Res 1994; 54: 1190-1193.
17. Aronica SM, Katzenellenbogen BS. Stimulation of estrogen receptor-mediated transcription and alteration in the phosphorylation state of the rat uterine estrogen receptor by estrogen, cyclic adenosine monophosphate, and insulin-like growth factor-I. Mol Endocrinol 1993; 7: 743-752.
18. Ignar-Trowbridge DM, Teng CT, Ross KA, Parker MG, Korach KS, McLahlan JA. Peptide growth factors elicit estrogen receptor-dependent transcriptional activation of an estrogen-responsive element. Mol Endocrinol 1993; 7: 992-998.
19. Beck CA, Weigel NL, Moyer ML, Nordeen SK, Edwards DP. The progesterone antagonist RU 486 acquires agonist activity upon stimulation of cAMP signalling pathways. Proc Natl Acad Sci USA 1993; 90: 4441-4445.
20. Kaighn ME, Shankar Narayan K, Ohnuki Y, Lechner JF, Jones LW. Establishment and characterization of a human prostatic cell line (PC-3). Int J Cancer 1978; 21: 274-281.
21. Stone KR, Mickey DD, Wunderli H, Mickey GH, Paulson DF. Isolation of a human prostate carcinoma cell line (DU 145). Int J Cancer 1978; 21: 274-281.
22. Horoszewicz JS, Leoung SS, Kawinski E, et al. LNCaP model of human prostatic carcinoma. Cancer Res 1983; 43: 1809-1818.
23. Mostofi FK, Sesterhenn IA, Sobin LH. Histological typing of prostate tumors. In: WHO Monograph Series No. 22. Geneva: WHO, 1980.
24. Culig Z, Klocker H, Eberle J, et al. DNA sequence of the androgen receptor in prostatic tumor cell lines and tissue specimens assessed by means of the polymerase chain reaction. Prostate 1993; 22: 11-22.
25. EORTC Breast Cancer Cooperative Group. Revision of the standard for the assessment of hormone receptors in human breast cancer. Eur J Cancer 1980; 16: 1513-1515.
26. Koenders A, Thorpe SM on behalf of the EORTC Receptor Group. Standardization of steroid receptor assays in human breast cancer. II. Samples with low receptor content. Eur J Cancer 1983; 19: 1467-1472.
27. Berthoid Y, Katzenellenbogen JA, Katzenellenbogen BS. Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture. Proc Natl Acad Sci USA 1990; 83: 2496-2500.
28. Viljoen TC, van Aswegen CH, du Plessis DJ. Binding of estradiol to whole prostatic DU-145 cells in the presence and absence of tamoxifen and acetylsalicylic acid. Prostate 1995; 27: 160-165.
29. Hobisch A, Culig Z, Radmayr C, Bartsch G, Klocker H, Hittmair A. Distant metastases from prostatic carcinoma express androgen receptor protein. Cancer Res 1995; 55: 3068-3072.
30. Hobisch A, Culig Z, Radmayr C, Bartsch G, Klocker H, Hittmair A. Androgen receptor status of lymph node metastates from prostatic carcinoma. Prostate 1996; 28: 129-135.
31. Taplin ME, Bubley GJ, Shuster TD, et al Mutation of the androgen receptor gene in metastatic androgen-independent prostate cancer. N Engl J Med 1995; 332: 1393-1398.
32. Culig Z, Hobisch A, Cronauer MV, et al. Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. Cancer Res 1994; 54: 5474-5478.
33. Ikonen T, Palvimo JJ, Kallio PJ, Reinikainen P, Jänne OA. Stimulation of androgen-regulated transactivation by modulators of protein phosphorylation. Endocrinology 1994; 135: 1359-1366.
34. Cooke PS, Young P, Hess RA, Cunha GR. Estrogen receptor expression in developing epididymis, efferent ductules, and other male reproductive organs. Endocrinology 1991; 128: 2874-2879.
35. Ehara H, Koji T, Deguchi T, et al. Expression of estrogen receptor in diseased human prostate assessed by non-radioactive in situ hybridization and immunohistochemistry. Prostate 1995; 27: 304-313.
36. Kirschenbaum A, Ren M, Erenburg I, Scachter B, Levine AC. Estrogen receptor messenger RNA in benign prostatic hyperplasia: detection, localization, and modulation with a long-acting gonadotropin-releasing hormone agonist. J Androl 1994; 15: 528-533.
37. Kruithof-Dekker IG, Tetu B, Janssen PJA, van der Kwast TH. Elevated estrogen receptor expression in human prostatic stromal cells by androgen ablation therapy. J Urol 1996; 156: 1194-1197.
38. Kemppainen JA, Lane MV, Sar M, Wilson EM. Androgen receptor phosphorylation, turnover, nuclear transport, and transcriptional activation. J Biol Chem 1992; 267: 968-974.
39. Klocker H, Culig Z, Hobisch A, Cato ACB, Bartsch G. Androgen receptor alterations in prostatic carcinoma. Prostate 1994; 25: 266-273.