Structure and expression of aminopeptidase N

Advances in Experimental Medicine and Biology

Volumn 421, Issue , 1997, Pages 47-57

  Olsen, Jørgen ^a   Kokholm, Klaus ^a   Norén, Ove ^a   Sjöström, Hans ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MEMBRANE PROTEIN; MICROSOMAL AMINOPEPTIDASE;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; COVALENT BOND; DNA SEQUENCE; ELECTRON MICROSCOPY; ENZYME STRUCTURE; INTESTINE ABSORPTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION;

ANIMALIA;

EID: 0030873817     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4757-9613-1_7     Document Type: Article

References (72)

1. Norén O, Sjöström H, Danielsen EM, et al. Desnuelle P, Sjöström H, Norén O, editors.Molecular and cellular basis of digestion. Elsevier Science Publishers B.V. 1986; 19. The enzymes of the enterocyle plasma membrane, p. 335-65.
2. Kenny AJ, Stephenson LS, Turner AJ. ; Kenny AJ, Turner AJ, editors.Mammalian ectoenzymes. Amsterdam: Elsevier Science Publishers B.V. 1987; 7, Cell surface peptidases. p. 169-210.
3. Classen-Linke I, Denker H-W, Winterhager E. Apical plasma membrane-bound enzymes of rabbit uterine epithelium. Pattern changes during the periimplantation phase. Histochemistry 1987;87;517-29.
4. Larsen SL, Pedersen LO, Buus S, Stryhn A. T cell responses affected by aminopeptidase N (CD13)-mediated trimming of major histocompatibility complex class II-bound peptides. J Exp Med 1996; 184: 183-9.
5. Danielsen EM, Cowell GM, Noren O, et al. Kenny AJ, Turner AJ, editors.Mammalian ectoenzymes. Amsterdam: Elsevier Science Pbulishers B.V. 1987; 3. Biosynthesis, p. 47-85.
6. Danielsen EM, Cowell GM, Norën O, Sjöström H. Biosynthesis of microvillar proteins. Biochem J 1984;221:1-14.
7. Hussain MM, Tranum-Jensen J, Norén O, Sjöström H, Christiansen K. Reconstitution of purified amphiphilic pig intestinal microvillus aminopeptidase. Mode of membrane insertion and morphology. Biochem J 1981;199:179-86.
8. Olsen J, Cowel GM, Knigshfer E, Danielsen EM, Muller J, Laustsen L, Hansen OC, Welinder KG, Engberg J, Hunziker W, Spies M, Sjöström H, Norén O. Complete amino acid sequence of human intestinal aminopeptidase N as deduced from cloned cDNA. FEBS Lett 1988;238:307-14.
9. Look AT, Ashmun RA, Shapiro LH, Peiper SC. Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N. J Clin Invest 1989;83:1299-307.
10. Danielsen EM. Tyrosine sulfation, a post-translational modification of microvillar enzymes in the small intestinal enterocyte. EMBO J 1987;6:2891-6.
11. Hooper NM. Families of zinc metalloproteases. [Review]. FEBS Letters 1994:354:1-6.
12. McCaman MT, Gabe JD. The nucleotide sequence of the pepN gene and its over-expression in Escherichia coli. Gene 1986;48:145-53.
13. Foglino M, Gharbi S, Lazdunski A. Nucleotide sequence of the pepN gene encoding aminopeptidase N of Escherichia coli. Gene 1986;49:303-9.
14. Delmas B, Gelfi J, L'Haridon R, Vogel LK, Sjöströ.m H, Norén O, Laude, H, Aminopeptidase N is a major receptor for the entero-pathogenic coronavirus TGEV. Nature 1992;357:417-20.
15. Yeager CL, Ashmun RA, Williams RK, Cardellichio CB, Shapiro LH, Look. AT, Holmes KV. Human aminopeptidase N is a receptor for human coronavirus 229E. Nature 1992;357:420-2.
16. Gordon JI. Intestinal epithelial differentiation: new insights from chimeric and transgenic mice. J Cell Biol 1989;108:1187-94.
17. Simon TC, Gordon JI. Intestinal epithelial cell differentiation: new insights from mice, flies and nematodes. Curr Opin Genet Develop 1995;5:557-86.
18. Hansen GH, Niels-Christiansen LL, Poulsen MD, Norén O, Sjöström H. Distribution of three microvillar enzymes along the small intestinal crypt-villus axis. J Submicrosc Cytol Pathol 1994;26:453-60.
19. Norén O, Dabelsteen E, Høyer PE, Olsen J, Sjöström H, Hansen GH. Onset of transcription of the aminopeptidase N (leukemia antigen CD13) gene at the crypt/villus transition zone during rabbit enterocyte differentiation. FEBS Lett 1989;259:107-12.
20. Hansen GH, Sjöström H, Norén O, Dabelsteen E. Immunomiscroscopic localization of aminopeptidase N in pig enterocyte. Implications for the route of intercellular transport. Eur J Cell Biol 1987;43:253-9.
21. Wessels HP, Hansen GH, Fuhrer C, Look AT, Sjöström H, Norén O, Spiess M. Aminopeptidase N is directly sorted to the apical domain in MDCK. cells. J Cell Biol 1990;111:2923-30.
22. Vogel LK, Spiess M, Sjöström H, Norén O. Evidence for an apical sorting signal on the ectodomain of human aminopeptidase N. J Biol Chem 1992:267:2794-7.
23. Vogel LK, Norén O, Sjöström H. Transcytosis of aminopeptidase N in Caco-2 cells is mediated by a noncytoplasmic signal. J Biol Chem 1995;270:22933-8.
24. Look AT, Peiper SC, Rebentisch MB, Ashmun RA, Roussel MF, Lemons RS, Le Beau MM, Rubin CM, Sherr CJ. Molecular cloning, expression, and chromosomal localization of the gene encoding a human myeloid membrane antigen (gp150). J Clin Invest 1986;78:914-21.
25. Olsen J, Sjöström H, Norén O. Cloning of the pig aminopeptidase N gene. Identification of possible regulatory elements and the exon distribution in relation to the membrane-spanning region. FEBS Letters 1989;251:275-81.
26. Kruse TA, Bolund L, Grzeschik KH, Ropers HH, Olsen J, Sjöström H, Norén O. Assignment of the human aminopeptidase N (peptidase E) gene to chromosome 15q13-qter. FEBS Letters 1988:239:305-8.
27. Poulsen PH, Thomsen PD, Olsen J. Assignment of the porcine aminopeptidase N (PEPN) gene to chromosome 7cenq21. Cytogenet Cell Genet 1991;57:44-6.
28. Lerche C, Vogel LK, Shapiro LH, Norén O. Sjöström H. Human aminopeptidase N is encoded by 20 exons. Mamm Genome 1996;7 In Press.
29. Olsen J, Laustsen L, Kärnström U, Sjöström H, Norén O. Tissue-specific interactions between nuclear proteins and the aminopeptidase N promoter. J Biol Chem 1991;266:18089-96.
30. Shapiro LH, Ashmun RA, Roberts WM, Look T. Separate promoters control transcription of the human aminopeptidase N gene in myeloid and intestinal epithelial cells. J Biol Chem 1991;266:11999-2007
31. Olsen J, Classen-Linke I, Sjöström H, Norén O. Pseudopregnancy induces the expression of hepatocyte nuclear factor-1 beta and its target gene aminopeptidase N in rabbit endometrium via the epithelial promoter. Biochem J 1995;312:31-7.
32. Olsen J, Kokholm K, Troelsen JT, Laustsen L. An enhancer with cell-type specific activity is located between the myeloid and epithelial aminipeptidase N (CD13) promoters. Manuscript 1996
33. Olsen J, Laustsen L, Troelsen J. HNF1a activates the aminopeptidase N promoter in intestinal (Caco-2) cells. FEBS Lett 1994;342:325-8.
34. Courey AJ, Tjian R. Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell 1988;55:887-98.
35. Kadonaga JT, Courey AJ, Ladika J, Tjian R. Distinct regions of Sp1 modulate DNA binding and transcriptional activation. Science 1988;242:1566-70.
36. Kadonaga JT, Carner KR, Masiarz FR, Tjian R. Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. Cell 1987;51:1079-90.
37. Briggs MR, Kadonaga JT, Bell SP, Tjian R. Purification and biochemical characterization of the promoter-specific transcription factor, Spl. Science 1986;234:47-52.
38. Kadonaga JT, Katherine A, Tjian R. Promoter-specific activation of RNA polymerase II transcription by Sp1. Trends Biochem Sci 1986;11:20-3.
39. Hagen G, Dennig J, Preiss A, Beato M, Suske G. Functional analyses of the transcription factor Sp4 reveal properties distinct from Sp1 and Sp3. J Biol Chem 1995;270:24989-94.
40. Hagen G, Muller S, Beato M, Suske G. Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes. Nucleic Acids Res 1992;20:5519-25.
41. Hagen G, Muller S, Beato M, Suske G. Sp1-mediated transcriptional activation is repressed by Sp3-EMBO J 1994;13:3843-51.
42. Tronche F, Yaniv M. HNF1, a homeoprotein member of the hepatic transcription regulatory network. BioEssays 1992;14:579-87.
43. Mendel DB, Crabtree GR. HNF-1, a member of a novel class of dimerizing homeodomain proteins. J Biol Chem 1991;266:677-80.
44. Lai E, Darnell JEJ Transcriptional control in hepatocytes: a window on development. Trends Biochem Sci 1991;16:427-9.
45. De Simone V, Cortese R. Transcription factors and liver-specific genes. Biochim Biophys Acta 1992;1132:119-26.
46. Nicosia A, Monaci P, Tomei L, De Francesco R, Nuzzo M, Stunnenberg H, Cortese R. A myosin-like dimerization helix and an extra-large homeodomain are essential elements of the tripartite DNA binding structure of LFB1. Cell 1990;61:1225-36.
47. Mendel DB, Hansen LP, Graves MK, Conley PB, Crabtree GR. HNF-1α and HNF1 (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro. Genes & Dev 1991;5:1042-56.
48. Rey-Campos J, Chouard T, Yaniv M, Cereghini S. vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1. EMBO J 1991;10:1445-57.
49. De Simone V, De Magistris L, Lazzaro D, Gerstner J, Monaci P, Nicossia A, Cortese R. LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia. EMBO J 1991;10:1435-43.
50. Bach I, Yaniv M. More potent transcriptional activators or a transdominant inhibitor of the HNF1 homeoprotein family are generated by alternative RNA processing. EMBO J 1993;12:4229-42.
51. Cereghini S, Ott M-O, Power S, Maury M. Expression patterns of vHNF1 and HNF1 homeoproteins in early postimplantation embryos suggest distinct and sequential developmental roles. Development 1992;116:783-97.
52. Blumenfeld M, Maury M, Chouard T, Yaniv M, Condamine H. Hepatic nuclear factor 1 (HNF1) shows a wider distribution than products of its known target genes in developing mouse. Development 1991;113:589-99.
53. Wang LH, Tsai SY, Cook RG, Beattie WG, Tsai MJ, O'Malley BW. COUP transcription factor is a member of the steroid receptor superfamily. Nature 1989;340:163-6.
54. Riemann D, Gohring B, Langner J. Expression of aminopeptidase N/CD13 in tumour-infiltrating lymphocytes from human renal cell carcinoma. Immunol Lett 1994;42:19-23.
55. Wex T, Lendeckel U, Wex H, Frank K, Ansorge S. Quantification of aminopeptidase N mRNA in T cells by competitive PCR. FEBS Lett 1995;374:341-1.
56. Lendeckel U, Wex T, Kahne T, Frank K, Reinhold D, Ansorge S. Expression of the aminopeptidase N (CD13) gene in the human T cell lines HuT78 and H9. Cell Immunol 1994;153:214-26.
57. Shapiro LH. Myb and Ets proteins cooperate to transactivate an early myeloid gene. J Biol Chem 1995;270:8763-71.
58. Mucenski ML, McLain K, Kier AB, Swerdlow SH, Schreiner CM, Miller TA, Pietryga DW, Scott WJ, Jr., Potter SS. A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell 1991;65:677-89.
59. Metz T, Graf T. v-myb and v-ets transform chicken erythroid cells and cooperate both in trans and in cis to induce distinct differentiation phenotypes. Genes & Dev 1991;5:369-80.
60. Melotti P, Calabretta B. Ets-2 and c-Myb act independently in regulating expression of the hematopoietic stem cell antigen CD34. J Biol Chem 1994;269:25303-9.
61. Dudek H, Tantravahi RV, Rao VN, Reddy ES, Reddy EP. Myb and Ets proteins cooperate in transcriptional activation of the mim-1 promoter. Proc Natl Acad Sci USA 1992;89:1291-5.
62. Nunn MF, Seeburg PH, Moscovici C, Duesberg PH. Tripartite structure of the avian erythroblastosis virus E26 transforming gene. Nature 1983;306:391-5.
63. Leprince D, Gegonne A, Coll J, de Taisne C, Schneeberger A, Lagrou C, Stehelin D. A putative second cell-derived oncogene of the avian leukaemia retrovirus E26. Nature 1983;306:395-7.
64. Wasylyk B, Hahn SL, Giovane A. The Ets family of transcription factors [published erratum appears in Eur J Biochem 1993 Aug 1;215(3):907]. [Review]. Eur J Biochem 1993;211:7-18.
65. Lozzio CB, Lozzio BB. Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. Blood 1975;45:321-34.
66. Hay R, Caputo J, Chen TR, et al. American Type Culture Collection. Catalogue of Cell Lines and Hybridomas. 7th ed. Rockville, Maryland: American Type Culture Collection; 1992.
67. Treisman R. Ternary complex factors: growth factor regulated transcriptional activators. Curr Opin Genet Develop 1994;4:96-101.
68. Treisman R. The serum response element. Trends Biochem Sci 1992;17:423-6.
69. Riemann D, Kehlen A, Langner J. Stimulation of the expression and the enzyme activity of aminopeptidase N/CD13 and dipeptidylpeptidase IV/CD26 on human renal cell carcinoma cells and renal tubular epithelial cells by T cell-derived cytokines, such as IL-4 and IL-13. Clin Exp Immunol 1995;100:277-83.
70. Foltzer-Jourdainne C, Raul F. Effect of epidermal growth factor on the expression of digestive hydrolases in the jejunum and colon of newborn rats. Endocrinology 1990;127:1763-9.
71. Xin JH, Cowie A, Lachance P, Hassell JA. Molecular cloning and characterization of PE A3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells. Genes & Dev 1992;6:481-96.
72. Rehfeld N, Peters JE, Giesecke H, Haschen RJ. Untersuchungen über aminosaüre-arylamidasen. I Verteilung und isoenzyme der aryl-amidase im menschlichen Organismus. Acta Biologica et Medica Germanica 1967;19:819-30.