p53 is involved in the inhibition of cell proliferation mediated by activin A in cultured human prostate cancer LNCaP cells

International Journal of Oncology

Volumn 11, Issue 3, 1997, Pages 591-595

  Ying, Shao Yao ^a   Zhang, Zhong ^a   Batres, Yasir ^a   Zhao, Yanle ^a   Lin, Shih Lung ^a   Li, Guangwu ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Activin receptors; Autocrine; Cell proliferation; DU 145; PC3; Prostate cancer

Indexed keywords

ACTIVIN A; ANDROGEN; MESSENGER RNA; PROTEIN P53;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; GROWTH INHIBITION; HORMONE SENSITIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CANCER;

EID: 0030872853     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.11.3.591     Document Type: Article

References (33)

1. Ying S-Y: Inhibins, activins, and follistatins: gonadal proteins modulating the secretion of follicle-stimulating hormone. Endocrinol Rev 9: 267-293, 1988.
2. Ying S-Y, Becker A, Ling N, Ueno N and Guillemin R: Inhibin and beta type transforming growth factor (TGFB) have opposite modulating effects on the follicle stimulating hormone (FSH)-induced aromatase activity of cultured rat granulosa cells. Biochem Biophys Res Commun 136: 969-975, 1986.
3. Meunier H, Rivier C, Evans RM and Vale W: Gonadal and extra-gonadal expression of inhibin α-, βA-, and βB-subunits in various tissues predicts diverse functions. Proc Natl Acad Sci USA 85: 247-251, 1988.
4. Tuuri T, Eramaa M, Hilden K and Ritvos O: The tissue distribution of activin βA- and βB-subunit and follistatin messenger ribonucleic acids suggests multiple sites of action for the activin-follistatin system during human development. J Clin Endocrinol Metab 78: 1521-1524, 1994.
5. Gonzalez-Manchon C and Vale W: Activin A, inhibin and transforming growth factor-β modulate growth of two gonadal cell lines. Endocrinology 125: 1666-1672, 1989.
6. Kojima I and Ogata E: Dual effect of activin A on cell growth .in Balb/c 3T3 cells. Biochem Biophys Res Commun 159: 1107-1113, 1989.
7. Ying S-Y, Zhang Z and Huang G: Expressiom and localization of inhibin/activin subunits and activin receptors in the normal rat prostate. Life Sci 60: 397-401, 1997.
8. Ying S-Y, Zhang Z and Xing W: Expression of activin and activin receptors in PC3 human prostatic cancer cells. Int J Oncol 6: 601-606, 1995.
9. Berta Y, Zhang Z and Ying S-Y: Expression of activins and activin receptors messenger RNAs in LNCaP cells, a human prostatic adenocarcinoma cell line. Int J Oncol 6: 1185-1188, 1995.
10. Furst BA, Zhang Z and Ying S-Y: Expression of activins and activin receptors in human prostate carcinoma cell line DU145. Int J Oncol 7: 239-243, 1995.
11. Wang QF, Tilly KI, Tilly JL, Preffer F, Schneyer AL, Crowley WF Jr and Sluss PF: Activin inhibits basal and androgen-stimulated proliferation and induces apoptosis in the human prostatic cancer cell line, LNCaP. Endocrinology 137: 5476-5483, 1996.
12. Dalkin AC, Gilrain JT, Bradshaw D and Myers CE: Activin inhibition of prostate cancer cell growth: selective actions on androgen-responsive LNCaP cells. Endocrinology 137: 5235-5330, 1996.
13. Ying SY, Zhang Z, Furst B, Batres Y, Huang G and Li G: Activins and activin receptors in cell growth. Proc Soc Exp Biol Med 214: 114-122, 1997.
14. Zhang Z, Zhao Y, Batres Y, Lin MF and Ying S-Y: Regulation of growth and prostatic marker expression by activin A in an androgen-sensitive prostate cancer cell line LNCaP. Biochem Biophys Res Commun 234: 362-365, 1997.
15. Elwart E and Dormer P: Effect of 5-fluoro-2′-deoxyuridine (FdUrd) on 5-bromo-2′-deoxyuridine (BrdUrd) incorporation into DNA measured with monoclonal BrdUrd antibody and by the BrdUrd/Hoechst quenching effect. Cytometry 6: 513-520, 1985.
16. Roberts AR, Flanders KC, Heine UI, Jakowlew S, Komdaiah P, Kim SJ and Sporn MB: Transforming growth factor-β: multifunctional regulator of differentiation and development. Philos Trans R Soc Lond (B) 327: 145-154, 1990.
17. Story MT, Livingston B, Baeton L, Swartz SJ, Jacobs SC, Begun FP and Lawson RK: Cultured human prostate derived fibroblasts produce a factor that stimulates their growth with properties indistiguishable from basic fibroblast growth factor. Prostate 15: 355-365, 1989.
18. Begun FP, Story MT, Hopp KA, Shapiro E and Lawson RK: Regional concentration of basic fibroblast growth factor in normal and benign hyperplastic human prostates. J Urol 153: 839-843, 1995.
19. Muller WJ, Lee FS, Dickson C, Petters G, Pattengale P and Leder P: The int-2 gene product acts as an epithelia growth factor in transgenic mice. EMBO J 9: 907-913, 1990.
20. Nakamoto T, Chang C, Li A and Chodak GW: Basic fibroblast growth factor in human prostate cancer cells. Cancer Res 52: 571-577, 1992.
21. Perkel VS, Mohan S, Herning SJ, Baylins DJ and Linkhart TA: Human prostatic cancer cells, PC-3 elaborate mitogenic activity which selectively stimulates human bones cells. Cancer Res 50: 6902-6907, 1990.
22. Pietrzkowski Z, Mulholland G, Comella L, Hameson BA, Weinike D and Baserga R: Inhibition of growth of prostatic cancer cell lines by peptides of insulin-like growth factor I. Cancer Res 53: 1102-1106, 1993.
23. Connolly JM and Rose DP: Regulation of DU145 human prostate cancer cell proliferation by insulin-like growth factors and its interaction with the epidermal growth factor autocrine loop. Prostate 24: 167-175, 1994.
24. Wilding G, Zugmeier G, Knabbe C, Flanders K, Gelmann E: Differential effects of transforming growth factor beta on human prostate cancer cells in vitro. Mol Cell Endocrinol 62: 79-87, 1989.
25. Schurrmans ALG, Bolt J and Mulder E: Androgens and transforming growth factor β modulate the grow response to epidermal grow factor in human prostatic tumor cells (LNCaP). Mol Cell Endocrinol 60: 101-104, 1988.
26. Watts RG and Ware JL: Isolation and characterization of transforming growth factor beta response variants from human prostatic tumor cell lines. Prostate 21: 223-237, 1992.
27. Sehy DW, Shao LE, Yu AL, Tsai WM and Yu J: Activin A-induced differentiation in K563 cells is associated with a transient hypophosphorylation of RB protein and the concomitant block of cell cycle at G, phase. J Cell Biochem 50: 255-265, 1992.
28. 3H]thymidine uptake by rat thymocytes and 3T3 cells in vitro. Mol Cell Endocrinol 61: 133-138, 1989.
29. Ying S-Y and Becker A: Inhibin and activin modulate transforming growth factor-β (TGFβ)-induced immunosuppression. J Biomed Sci 2: 237-241, 1996.
30. Yasuda H, Mine T, Shibata H, Eto Y, Hasegawa Y, Takeuchi T, Asano S and Kojima I: Activin A: an autocrine inhibitor of initiation of DNA synthesis in rat hepatocytes. J Clin Invest 92: 1491-1496, 1994.
31. McCarthy S and Bicknell R: Inhibition of vascular endothelial cell growth by activin-A. J Biol Chem 268: 23066-23071, 1993.
32. Wang T, Danielson PD, Li B, Shah PC, Kim SD and Donahoe PK: The p21 (RAS) farnesyltransferase alpha subunit in TGF-β and activin signaling. Science 271: 1120-1122, 1996.
33. Carcamo J, Weiss FM, Ventura F, Wieser R, Wrana JL, Attisano L and Massague J: Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor β and activin. Mol Cell Biol 14: 3810-3821, 1994.