Characterization of a specific region in the hepatitis B virus enhancer I for the efficient expression of X gene in the hepatic cell

Virology

Volumn 236, Issue 2, 1997, Pages 279-287

  Fukai, Kenichi ^a,b   Takada, Shinako ^a   Yokosuka, Osamu ^b   Saisho, Hiromitsu ^b   Omata, Masao ^c   Koike, Katsuro ^a  

^a CANCER INSTITUTE   (Japan)

^b CHIBA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONTROLLED STUDY; ENHANCER REGION; GENE EXPRESSION; GENETIC TRANSFECTION; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; VIRUS TRANSCRIPTION;

HEPATITIS B VIRUS;

EID: 0030865699     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1997.8750     Document Type: Article

References (61)

1. Antonucci T. K., Rutter W. J. Hepatitis B virus (HBV) promoters are regulated by the HBV enhancer in a tissue-specific manner. J. Virol. 63:1989;579-583.
2. Auge-Gouillou C., Petropoulos I., Zakin M. M. Liver-enriched HNF-3-alpha and ubiquitous factors interact with the human transferrin gene enhancer. FEBS Lett. 323:1993;4-10.
3. Beasley R. P., Lin C. C., Hwang L. Y., Chien C. S. Hepatocellular carcinoma and hepatitis B virus: A prospective study of 22,707 men in Taiwan. Lancet. ii:1981;1129-1133.
4. Ben-Levy R., Faktor O., Berger I., Shaul Y. Cellular factors that interact with the hepatitis B virus enhancer. Mol. Cell. Biol. 9:1989;1804-1809.
5. Ben-Shushan E., Sharir H., Pikarsky E., Bergman Y. A dynamic balance between APR-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor: Retinoid X receptor heterodimers regulates oct-3/4 expression in embryonal carcinoma cells. Mol. Cell. Biol. 15:1995;1034-1048.
6. Chen M., Hieng S., Qian X., Costa R., Ou J. H. Regulation of hepatitis B virus ENI enhancer activity by hepatocyte-enriched transcription factor HNF3. Virology. 205:1994;127-132.
7. Costa H. R., Grayson D. R., Darnell J. E. Jr. Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and α1-antitrypsin gene. Mol. Cell. Biol. 9:1989;1415-1425.
8. Dignam J. D., Lebowitz R. M., Roeder R. G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1983;1475-1489.
9. Dikstein R., Faktor O., Ben-Levy R., Shaul Y. Functional organization of the hepatitis B virus enhancer. Mol. Cell. Biol. 10:1990;3683-3689.
10. Faktor O., Budlovsky S., Ben-Levy R., Shaul Y. A single element within the hepatitis B virus enhancer binds multiple proteins and responds to multiple stimuli. J. Virol. 64:1990;1861-1863.
11. Fuernkranz H. A., Wang Y., Karathanasis S. K., Mak P. Transcriptional regulation of the apoAI gene by hepatic nuclear factor 4 in yeast. Nucleic Acids Res. 22:1994;5665-5671.
12. Ganem D., Varmus H. E. The molecular biology of the hepatitis B virus. Annu. Rev. Biochem. 56:1987;651-693.
13. Garcia A. D., Ostapchuk P., Hearing P. Functional interaction of nuclear factors EF-C, HNF-4, and RXRα with hepatitis B virus enhancer I. J. Virol. 67:1993;3940-3950.
14. Gorman C. M., Moffat L. F., Howard B. H. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1982;1044-1051.
15. Graham F. L., Van-Der-Eb A. J. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology. 52:1973;456-467.
16. Gregori C., Kahn A., Pichard A. L. Competition between transcription factors HNF1 and HNF3, and alternative cell-specific activation by DBP and C/EBP contribute to the regulation of the liver-specific aldolase B promoter. Nucleic Acids Res. 21:1993;897-903.
17. Herbomel P., Bourachot B., Yaniv M. Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma. Cell. 39:1984;653-662.
18. Huan B., Kosovsky M. J., Siddiqui A. Retinoid X receptor α transactivates the hepatitis B virus enhancer I element by forming a heterodimeric complex with the peroxisome proliferator-activated receptor. J. Virol. 69:1995;547-551.
19. Huan B., Siddiqui A. Retinoid X receptor RXRα binds to and trans-activates the hepatitis B virus enhancer. Proc. Natl. Acad. Sci. USA. 89:1992;9059-9063.
20. Ip Y. T., Poon D., Stone D., Granner D. K., Chalkley R. Interaction of a liver-specific factor with an enhancer 4.8 kilobases upstream of the phosphoenolpyruvate carboxykinase gene. Mol. Cell. Biol. 10:1990;3770-3781.
21. Jackson D. A., Rowader K. E., Steven K., Jiang C. Y., Milos P., Zaret K. S. Modulation of liver-specific transcription by interactions between hepatocyte nuclear factor 3 and nuclear factor 1 binding DNA in close apposition. Mol. Cell. Biol. 13:1993;2401-2410.
22. Jameel S., Siddiqui A. The human hepatitis B virus enhancer requires trans-acting cellular factor(s) for activity. Mol. Cell. Biol. 6:1986;710-715.
23. Jiang G., Nepomuceno L., Hopkins K., Sladek F. M. Exclusive homodimerization of the orphan receptor hepatocyte nuclear factor 4 defines a new subclass of nuclear receptors. Mol. Cell. Biol. 15:1995;5131-5143.
24. Kliewer S. A., Umesono K., Heyman R. A., Mangelsdorf D. J., Dyck J. A., Evans R. M. Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling. Proc. Natl. Acad. Sci. USA. 89:1992a;1448-1452.
25. Kliewer S. A., Umesono K., Noonan D. J., Heyman R. A., Evans R. M. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature. 358:1992b;771-774.
26. Kobayashi M., Koike K. Complete nucleotide sequence of hepatitis B virus DNA of subtype adr and its conserved gene organization. Gene. 30:1984;227-232.
27. Lai E., Prezioso V. R., Smith E., Levin O., Costa R. H., Darnell J. E. Jr. HNF3-A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally. Genes Dev. 4:1990;1427-1436.
28. Lai E., Prezioso V. R., Tao W., Chen W. S., Darnell J. E. Jr. Hepatocyte nuclear factor 3α belongs to a gene family in mammals that is homologous to the drosophila homeotic gene fork head. Genes Dev. 5:1991;416-427.
29. Liu C., Mason W. S., Burch J. B. E. Identification of factor-binding sites in the duck hepatitis B virus enhancer and in vivo effects of enhancer mutations. J. Virol. 68:1994;2286-2296.
30. Lopez-Cabrera M., Letovsky J., Hu K. Q., Siddiqui A. Multiple liver-specific factors bind to the hepatitis B virus core/pregenomic promoter: Trans-activation and repression by CCAAT/enhancer binding protein. Proc. Natl. Acad. Sci. USA. 87:1990;5069-5073.
31. Mangelsdorf D. J., Borgmeyer U., Heyman R. A., Zhou J. Y., Ong E. S., Oro A. E., Kakizuka A., Evans R. M. Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes Dev. 6:1992;329-344.
32. Mangelsdorf D. J., Umesono K., Kliewer S. A., Borgmeyer U., Ong E. S., Evans R. M. A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR. Cell. 66:1991;555-561.
33. Metzger S., Halaas J. L., Breslow J. L., Sladek F. M. Orphan receptor HNF-4 and bZIP protein C/EBPα bind to overlapping regions of the apolipoprotein B gene promoter and synergistically activate transcription. J. Biol. Chem. 268:1993;16831-16838.
34. Mietus-Snyder M., Sladek F. M., Ginsburg G. S., Kuo C. F., Ladias J. A. A., Darnell J. E., Karathanasis S. K. Antagonism between apolipoprotein AI regulatory protein 1, EAR/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells. Mol. Cell. Biol. 12:1992;1708-1718.
35. Monaci P., Nicosia A., Cortese R. Two different liver-specific factors stimulate in vitro transcription from the human α1-antitrypsin promoter. EMBO J. 7:1988;2075-2087.
36. Nakamura I., Koike K. Identification of a binding protein to the X gene promoter region of hepatitis B virus. Virology. 191:1992;533-540.
37. Nishiyori A., Tashiro H., Kimura A., Akagi K., Yamamura K., Mori M., Takiguchi M. Determination of tissue specificity of the enhancer by combinatorial operation of tissue-enriched transcription factors; Both HNF-4 and C/EBPβ are required for liver-specific activity of the ornithine transcarbamylase enhancer. J. Biol. Chem. 269:1994;1323-1331.
38. Ori A., Atzmony D., Haviv I., Shaul Y. An NF1 motif plays a central role in hepatitis B virus enhancer. Virology. 204:1994;600-608.
39. Ori A., Shaul Y. Hepatitis B virus enhancer binds and is activated by the hepatocyte nuclear factor 3. Virology. 207:1995;98-106.
40. Ostapchuk P., Scheirle G., Hearing P. Binding of nuclear factor EF-C to a functional domain of the hepatitis B virus enhancer region. Mol. Cell. Biol. 9:1989;2787-2797.
41. Patel N. U., Jameel S., Isom H., Siddiqui A. Interaction between nuclear factors and the hepatitis B virus enhancer. J. Virol. 63:1989;5293-5301.
42. Raymondjean M., Pichard A. L., Gregori C., Ginot F., Kahn A. Interplay of an original combination of factors: C/EBP, NFY, HNF3 and HNF1 in the rat aldolase B gene promoter. Nucleic Acids Res. 19:1991;6145-6153.
43. Reith W., Ucla C., Barras E., Gaud A., Durand B., Herrero-Sanchez C., Kobr M., Mach B. RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins. Mol. Cell. Biol. 14:1994;1230-1244.
44. Roossinck M. J., Jameel S., Loukin S. H., Siddiqui A. Expression of hepatitis B viral core region in mammalian cells. Mol. Cell. Biol. 6:1986;1393-1400.
45. Sauer F., Hansen S. K., Tjian R. Multiple TAFs directing synergistic activation of transcription. Science. 270:1995;1783-1788.
46. Schaller H., Fischer M. Transcriptional control of hepadnavirus gene expression. Curr. Top. Microbiol. Immunol. 168:1991;21-39.
47. Shaul Y., Rutter W. J., Laub O. A human hepatitis B viral enhancer element. EMBO J. 4:1985;427-430.
48. Sladek F. M., Zhong W., Lai E., Darnell J. E. Jr. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev. 4:1990;2353-2365.
49. Su H., Yee J. K. Regulation of hepatitis B virus gene expression by its two enhancer. Proc. Natl. Acad. Sci. USA. 89:1992;2708-2712.
50. Takada S., Kaneniwa N., Tsuchida N., Koike K. Hepatitis B virus X gene expression is activated by X protein but repressed by p53 tumor suppressor gene product in the transient expression system. Virology. 216:1996;80-89.
51. Tiollais P., Charnay P., Vyas G. N. Biology of hepatitis B virus. Science. 213:1981;406-411.
52. Tognoni A., Cattaneo R., Serfling E., Schaffner W. A novel expression selection approach allows precise mapping of the hepatitis B virus enhancer. Nucleic Acids Res. 13:1985;7457-7472.
53. Trujillo M. A., Letovsky J., Maguire H. F., Lopez-Cabrera M., Siddiqui A. Functional analysis of a liver-specific enhancer of the hepatitis B virus. Proc. Natl. Acad. Sci. USA. 88:1991;3797-3801.
54. Wu C., Wilson S., Walker B., Dawid I., Paisley T., Zimarino V., Ueda H. Purification and properties of Drosophila heat shock activator protein. Science. 238:1987;1247-1253.
55. Yaginuma K., Nakamura I., Takada S., Koike K. A transcription initiation site for the hepatitis B virus X gene is directed by the promoter-binding protein. J. Virol. 67:1993;2559-2565.
56. Yaginuma K., Shirakata Y., Kobayashi M., Koike K. Hepatitis B virus (HBV) particles are produced in a cell culture system by transient expression of transfected HBV DNA. Proc. Natl. Acad. Sci. USA. 84:1987;2678-2682.
57. Yanuka-Kashles O., Cohen H., Trus M., Aran A., Benvenisty N., Reshef L. Transcriptional regulation of the phosphoenolpyruvate carboxykinase gene by cooperation between hepatic nuclear factors. Mol. Cell. Biol. 14:1994;7124-7133.
58. Yee J. K. A liver-specific enhancer in the core promoter region of human hepatitis B virus. Science. 246:1989;658-661.
59. Yuh C. H., Chang Y. L., Ting L. P. Transcriptional regulation of precore and pregenomic RNAs of hepatitis B virus. J. Virol. 66:1992;4073-4084.
60. Yuh C. H., Ting L. P. The genome of hepatitis B virus contains a second enhancer: cooperation of two elements within this enhancer is required for its function. J. Virol. 64:1990;4281-4287.
61. Yuh C. H., Ting L. P. Differentiated liver cell specificity of the second enhancer of hepatitis B virus. J. Virol. 67:1993;142-149.