Expression of the transcription factor slug correlates with growth of the limb bud and is regulated by FGF-4 and retinoic acid

International Journal of Developmental Biology

Volumn 41, Issue 4, 1997, Pages 559-568

  Buxton, Paul G ^a   Kostakopoulou, Konstadina ^a,b   Brickell, Paul ^a   Thorogood, Peter ^a   Ferretti, Patrizia ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Development; FGF 4; Limb; Progress zone; Retinoic acid; Slug

Indexed keywords

FIBROBLAST GROWTH FACTOR 4; GENE PRODUCT; RETINOIC ACID; TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CHICK EMBRYO; GENE EXPRESSION; LIMB BUD; LIMB DEVELOPMENT; MESODERM; NEURAL CREST CELL; NONHUMAN; PRIORITY JOURNAL; SCLEROTOME;

ANIMALS; CELL DIFFERENTIATION; CHICK EMBRYO; ECTODERM; FIBROBLAST GROWTH FACTOR 4; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION; LIMB BUD; PROTO-ONCOGENE PROTEINS; TRANSCRIPTION FACTORS; TRETINOIN; ZINC FINGERS;

ANIMALIA; GASTROPODA;

EID: 0030863424     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. BUXTON, P.G., HUNT, P., FERRETTI, P and THOROGOOD, P. (1997) A role for midline closure in the reestablishment of dorsoventral pattern following dorsal hindbrain ablation. Dev. biol. 183: 150-165
2. COHN, M.J. and TICKLE, C. (1996). Limbs: a model for pattern formation within the vertebrate body plan. Trends Genet. 12: 253-257.
3. COHN, M.J., IZPISUA-BELMONTE, J.C , ABUD, H , HEATH, J.K. and TICKLE, C. (1995). Fibroblast growth factors induce additional limb development from the flank of chick embryos. Cell 80: 739-746.
4. CROSSLEY, P.M., MINOWADA, G , MACARTHUR, C.A and MARTIN, G.R. (1996). Roles for FGF8 in the induction, initiation, and maintenance of chick limb development Cell 84: 127-136.
5. DAVIDSON, D.R., CRAWLEY, A., HILL, R.E and TICKLE, C. (1991). Position-dependent expression of two related homeobox genes in developing vertebrate limbs. Nature 352: 429-31.
6. DUPREZ, D M., KOSTAKOPOULOU, K., FRANCIS-WEST, P.H., TICKLE, C. and BRICKELL, P.M. (1996). Activation of Fgf-4 and HoxD gene expression by BMP-2 expressing cells in the developing chick limb Development 122. 1821-1828.
7. FALLON, J.F , LÓPEZ, A , ROS, M.A., SAVAGE, M P., OLWIN, B.B. and SIMANDL, B.K. (1994). FGF-2: apical ectodermal ridge growth signal for chick limb development. Science 264: 104-107.
8. GOULDING, M.D., LUMSDEN, A. and GRUSS, P. (1993) Signals from the notochord and floorplate regulate the region-specific of two Pax genes in the developing spinal cord. Development 117: 1001-1016.
9. HAMBURGER, V. and HAMILTON, H.L. (1951). A senes of normal stages in the development of the chick embryo. J. Morphol. 88: 49-92
10. HELMS, J A., KIM, C.H., EICHELE, G. and THALLER, C. (1996). Retinoic acid signalling is required during early chick limb development. Development 122: 1385-1394.
11. HILL, R.E , JONES, P.F., REES, A.R., SIME, C.M., JUSTICE, M.J., COPELAND, N G., JENKINS, N A., GRAHAM, E. and DAVIDSON, D.R. (1989). A new family of mouse homeobox containing genes: molecular structure, chromosomal location and developmental expression of Hox-7.1. Genes Dev. 3: 26-37.
12. HINCHLIFFE, J.R. and JOHNSON, D.R (1980). The Development of the Vertebrate Limb. Oxford Science Publications, Clarendon Press, Oxford
13. KOSTAKOPOULOU, K., VOGEL, A., BRICKELL, P. and TICKLE, C. (1996). 'Regeneration' of wing bud stumps of chick embryos and reactivation of Msx-1 and Shh expression in response to FGF-4 and ndge signals. Mech. Dev. 55: 119-131.
14. LAUFER, E., NELSON, C.E., JOHNSON, R.L., MORGAN, B.A. and TABIN, C. (1994). Sonic hedgehog and FGF-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79: 993-1003.
15. LEE, J. and TICKLE, C. (1985). Retinoic acid and pattern formation in the developing chick wing: SEM and quantitative studies of early effects on the apical ectodermal ridge and bud outgrowth. J Embryol. Exp Morphol. 90: 139-169.
16. Li, S., ANDERSON, R., REGINELLI, A.D. and MUNEOKA, K. (1996). FGF-2 influences cell movement and gene expression during limb development. J. Exp. Zool. 274: 234-247.
17. MacCABE, J.A, SAUNDERS, J.W. and PICKETT, M. (1973). The control of the anteroposterior and dorsoventral axes in embryonic chick limbs constructed of dissociated and reaggregated limb-bud mesoderm. Dev. Biol. 31: 323-335.
18. MAHMOOD, R., BRESNICK, J., HORNBRUCH, A., MAHONY, C., MORTON, N., COLQUHOUN, K , MARTIN, P ., LUMSDEN, A., DICKSON, C. and MASON, I. (1995). A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth. Curr. Biol. 5: 797-806.
19. MANGELSDORF, D.J., UMESONO, K. and EVANS, R.M. (1994). The retinoid receptors. In The Retinoids. Biology, Chemistry and Medicine (Eds. M.B. Sporn, A B. Roberts and D S. Goodman). Raven Press, New York, pp. 319-349.
20. MAYOR, R., MORGAN, R. and SARGENT, M.G. (1995) Induction of the prospective neural crest of Xenopus. Development 121: 767-777.
21. NIETO, M.A., SARGENT, M G , WILKINSON, D.G. and COOKE, J. (1994). Control of cell behaviour during vertebrate development by Slug, a zinc finger gene. Science 264: 835-839.
22. NISWANDER, L., JEFFREY, S., MARTIN, G. and TICKLE, C. (1994). A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371. 609-612
23. NISWANDER, L., TICKLE, C., VOGEL, A., BOOTH, I. and MARTIN, G R. (1993). FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 75 579-87.
24. OSTER, G F., SHUBIN, N., MURRAY, J.D. and ALBRECH, P. (1988) Evolution and morphogenetic rules: the shape of the vertebrate limb in ontogeny and phylogeny. Evolution 42: 862-884.
25. PATEL, K , NITTENBERG, R., DSOUZA, D., IRVING, C., BURT, D , WILKINSON, D.G. and TICKLE, C. (1996) Expression and regulation of Cek-8, a cell to cell signalling receptor in developing chick limb buds. Development 122. 1147-1155.
26. PECORINO, L T., ENTWISTLE, A. and BROCKES, J.P (1996). Activation of a single retinoic acid receptor isoform mediates proximodistal respecification. Curr Biol. 6: 563-569.
27. PECORINO, LT., LO, D.C. and BROCKES, J.P. (1994). Isoform-specific induction of a retinoid-responsive antigen after biolistic transfection of chimaenc retinoic acid/ thyroid hormone receptors into a regenerating limb. Development 120: 325-333.
28. RIDDLE, R., JOHNSON, R., LAUFER, E. and TABIN, C. (1993). Sonic Hedgehog mediates the polarizing activity of the ZPA. Cell 75: 1401-1416.
29. ROBERT, B., LYONS, G., SIMANDL, B.K., KUROIWA, A. and BUCKINGHAM, M. (1991). The apical ectodermal ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds. Genes Dev 5: 2363-74.
30. ROBERT, B., SASSOON, D., JACQ, B., GEHRING, W and BUCKINGHAM, M. (1989). Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis. EMBO J 8: 91-100.
31. RUBIN, L. and SAUNDERS Jr, J.W (1972). Ectodermal-mesodermal interactions in the growth of limb buds in the chick embryo: constancy and temporal limits of the ectodermal induction. Dev. Biol. 28: 94-112.
32. SAUNDERS Jr, J W. (1948). The proximo-distal sequence of the origin of the parts of the chick wing and the role of the ectoderm J. Exp. Zool. 108: 363-404
33. SAUNDERS Jr, J.W. and GASSELING. M.T. (1968). Ectodermal-mesodermal interactions in the origin of limb symmetry. In Epithelial-mesenchymal Interactions (Eds. R. Fleishmajer and R.E. Billingham). Williams and Wilkins, Baltimore, pp. 78-97.
34. SAUNDERS Jr, J W., GASSELING, M W and CAIRNS, J.M (1959). The differentiation of prospective thigh mesoderm grafted beneath the apical ectodermal ridge of the wing bud in the chick embryo. Dev. Biol 1: 281-301
35. SAUNDERS, J.W.J. (1977). The experimental analysis of chick limb bud development In Vertebrate Limb and Somite Morphogenesis (Eds. D.A Ede, J.R. Hinchliffe and M Balls). University Press, Cambridge, pp. 1-24.
36. SCHILTHUIS, J.G., GANN, A.A. and BROCKES, J.P. (1993). Chimeric retinoic acid/ thyroid hormone receptors implicate RAR-alpha 1 as mediating growth inhibition by retinoic acid. EMBO J. 12: 3459-66.
37. SECHRIST, J , NIETO, M A , ZAMANIAN, R T. and BRONNER-FRASER, M (1995). Regulative response of the cranial neural tube after neural fold ablation: spatiotemporal nature of neural crest regeneration and up-regulation of slug. Development 121. 4103-4115.
38. STRATFORD, T., HORTON, C and MADEN, M (1996) Retinoic acid is required for the initiation of outgrowth in the chick limb bud. Curr. Biol. 6 1124-1133.
39. SUMMERBELL, D. (1974). A quantitative analysis of the effect of excision of the AER from the chick limb bud. J Embryol Exp. Morphol. 35: 241-260
40. SUMMERBELL, D., LEWIS, J. and WOLPERT, L. (1973). Positional information in chick limb morphogenesis. Nature 244. 492-496.
41. TABIN, C. (1995). The initiation of the limb bud: growth factors, Hox genes, and retinoids. Cell 80: 671-4.
42. TAYLOR, G.P. ANDERSON, R., REGINELLI, A.D. and MUNEOKA, K (1994) FGF-2 induces regeneration of the chick limb bud. Dev. Biol. 163: 282-4.
43. THOROGOOD, P.V. and HINCHLIFFE, J.R (1975). An analysis of the condensation process during chondrogenesis in the embryonic chick hind limb J. Embryol. Exp Morphol. 33: 581-606.
44. TICKLE, C. and EICHELE, G. (1994) Vertebrate limb development. Annu Rev Cell Biol. 10: 121 -152.
45. TICKLE, C , ALBERTS, B.M , WOLPERT, L. and LEE, J (1982). Local application of retinoic acid to the limb bud mimics the action of the polarizing region Nature 296 564-565.
46. TICKLE, C., CRAWLEY, A. and FARRAR, J. (1989) Retinoid acid application to the chick wing buds lead to a dose-dependent reorganization of the apical ectodermal ridge that is mediated by the mesenchyme. Development 106: 691 -705.
47. TICKLE, C., LEE, J. and EICHELE, G. (1985). A quantitative analysis of the effect of all-trans-retinoic acid on the pattern of chick wing development. Dev. Biol. 109: 82-95.
48. VARGESSON, N , CLARKE, J.D.W., VINCENT, K., COLES, C., WOLPERT, L. and TICKLE, C. (1997) Cell fate in the chick limb bud and relationship to gene expression. Development 124: 1909-1918
49. VOGEL, A. and TICKLE, C. (1993). FGF-4 maintains polarizing activity of posterior limb bud cells in vivo and in vitro. Development 119: 199-206.
50. VOGEL, A., RODRIGUEZ, C. and IZPISUA-BELMONTE, J.C (1996). Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb. Development 122. 1737-1750.
51. WILKINSON, D. G. (1992). Whole mount in situ hybridization of vertebrate embryos. In In Situ Hybridization: A Practical Approach (Ed D.G. Wilkinson). IRL Press, Oxford, pp. 75-83.
52. WOLPERT, L, LEWIS, J. and SUMMERBELL, D. (1975). Morphogenesis of the vertebrate limb In Cell Patterning, Vol. 29, new series. Associated Scientific Publishers. Amsterdam, pp. 95-119.