High incidence of Down's syndrome in infants of diabetic mothers

Archives of Disease in Childhood

Volumn 77, Issue 3, 1997, Pages 242-244

  Narchi, Hassib ^a   Kulaylat, Naji ^a  

^a Saudi Aramco Al Hasa Health Center   (Saudi Arabia)

Author keywords

Down's syndrome; Infants of diabetic mothers; Trisomy 21

Indexed keywords

ADULT; ARTICLE; CARBOHYDRATE METABOLISM; CHROMOSOME ANALYSIS; CLINICAL ARTICLE; DOWN SYNDROME; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INCIDENCE; INFANT; MALE; MATERNAL AGE; MATERNAL DIABETES MELLITUS; NEWBORN; PREGNANCY COMPLICATION; PRIORITY JOURNAL; RISK ASSESSMENT;

EID: 0030863410     PISSN: 00039888     EISSN: 14682044     Source Type: Journal    
DOI: 10.1136/adc.77.3.242     Document Type: Article

References (16)

1. National Diabetes Data Group. Classification diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 1979;28:1039-57.
2. Milunski A. Glucose intolerance in the parents of children with Down's syndrome. American Journal of Mental Deficiency 1970;74:475-8.
3. Nielsen J. Diabetes mellitus in patients with aneuploid chromosome aberrations and in their parents. Humangenetik 1972;16:165-70.
4. Becker KL, Hoffmann DL, Albert A, Underhahl LO, Mason ML. Klinefelter's syndrome. Arch Intern Med 1966; 118:314-21.
5. Menzinger G, Falluca F, Andreani D. Klinefelter's syndrome and diabetes mellitus. Lancet 1966;ii:747-8.
6. Forbes AP, Engel E. The high incidence of diabetes mellitus in 41 patients with gonadal dysgenesis and their close relatives. Metabolism 1963;12:428-39.
7. Lindsten J, Cerasi E, Luft R, Hultquist G. The occurrence of abnormal insulin and growth hormone (HGH) responses to sustained hyperglycemia in a disease with sex chromosome aberrations (Turner's syndrome). Acta Endocrinol 1967;56:107-31.
8. Menzinger G, Falluca F, Andreani D. Gonadal dyspenesis and diabetes. Lancet 1966;i:1269.
9. Nielsen J, Johansen K, Yde H. The frequency of diabetes mellitus in patients with Turner's syndrome and pure gonadal dysgenesis. Acta Endocrinol 1969;62:251-69.
10. Milunski A, Neurath PW. Diabetes mellitus in Down's syndrome. Arch Environ Health 1968;17:372-6.
11. Navarette VN, Torres IH, Rivera IR, Shor VP, Garcia PM. Maternal carbohydrate disorder and congenital malformations. Diabetes 1967;16:127-30.
12. Landing BH, Pettit MD, Wiens RL, Knowles H, Guest BM. Antithyroid antibodies and chronic thyroiditis in diabetes. J Clin Endocrinol 1963;23:119-20.
13. Schupf N, Kapell D, Lee JH, Ottman R, Mayeux R. Increased risk of Alzheimer's disease in mothers of adults with Down's syndrome. Lancet 1994;344:353-6.
14. Emanuel I, Sever LE, Milham S Jr, Thuline HC. Accelerated ageing in young mothers of children with Down's syndrome. Lancet 1972;ii:361-3.
15. Brook JD, Gosden RG, Chandley AC. Maternal ageing and aneuploid embryosevidence from the mouse that biological and not chronological age is the important influence. Hum Genet 1984;66:41-5.
16. Avramopoulos D, Mikkelsen M, Vassilopoulos D, Grigoriadou M, Petersen MB. Apolipoprotein E allele distribution in parents of Down's syndrome children. Lancet 1996;347: 862-5.