Apolipoprotein E allele distribution in parents of Down's syndrome children

Lancet

Volumn 347, Issue 9005, 1996, Pages 862-865

  Avramopoulos, Dimitris ^a   Mikkelsen, Margareta ^b   Vassilopoulos, Dimitris ^c   Grigoriadou, Maria ^a   Petersen, Michael B ^a,b,d  

^a Institute of Child Health   (Greece)

^b JOHN F KENNEDY INSTITUTE   (Denmark)

^c UNIVERSITY OF ATHENS   (Greece)

^d AGHIA SOPHIA CHILDREN S HOSPITAL   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E;

ADULT; ALLELE; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; DOWN SYNDROME; ERROR; FATHER; FEMALE; GENE FREQUENCY; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN EXPERIMENT; MALE; MATERNAL AGE; MEIOSIS; MOTHER; NORMAL HUMAN; OOCYTE; PARENT; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; TRISOMY 21;

EID: 0030010225     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(96)91346-X     Document Type: Article

References (37)

1. Hook EB. Down syndrome: frequency in human populations and factors pertinent to variation in rates. In: de la Cruz FF, Gerald PS, eds. Trisomy 21 (Down syndrome): research perspectives. Baltimore: University Park Press, 1981: 3-67.
2. Antonarakis SE, Lewis JG, Adelsberger PA, et al. Parental origin of the extra chromosome in trisomy 21 as indicated by analysis of DNA polymorphisms. N Engl J Med 1991; 324: 872-76.
3. Antonarakis SE, Petersen MB, Mclnnis MG, et al. The meiotic stage of nondisjunction in trisomy 21: determination by using DNA polymorphisms. Am J Hum Genet 1992; 50: 544-50.
4. Penrose LS. The relative effects of paternal and maternal age in mongolism. J Genet 1933; 27: 219-24.
5. Petersen MB, Antonarakis SE, Hassold TJ, et al. Paternal nondisjunction in trisomy 21: excess of male patients. Hum Molec Genet 1993; 2: 1691-95.
6. Davignon J, Gregg RE, Sing CF. Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis 1988; 8: 1-21.
7. Strittmatter WJ, Saunders AM, Schmechel D, et al. Apolipoprotein E: high-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993; 90: 1977-81.
8. Chartier-Harlin M-C, Parfitt M, Legrain S, et al. Apolipoprotein E, ∈4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region. Hum Molec Genet 1994; 3: 569-74.
9. Corder EH, Saunders AM, Strittmatter WJ, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993; 261: 921-23.
10. 1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments. Nature 1994; 372: 92-94.
11. Pickering-Brown SM, Mann DMA, Bourke JP, et al. Apolipoprotein E4 and Alzheimer's disease pathology in Lewy body disease and in other β-amyloid-forming diseases. Lancet 1994; 343: 1155.
12. Amouyel P, Vidal O, Launay JM, Laplanche JL. The apolipoprotein E alleles as major susceptibility factors for Creutzfeldt-Jakob disease. Lancet 1994; 344: 1315-18.
13. Saunders AM, Schmader K, Breitner JCS, et al. Apolipoprotein E ∈4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases. Lancet 1993; 342: 710-11.
14. Nakagawa Y, Kitamoto T, Furukawa H, Ogomori K, Tateishi J. Apolipoprotein E in Creuztfeldt-Jakob disease. Lancet 1995; 345: 68.
15. Corder EH, Saunders AM, Risch NJ, et al. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nature Genet 1994; 7: 180-84.
16. van Duijn CM, de Knijff P, Wehnert A, et al. The apolipoprotein E ∈2 allele is associated with an increased risk of early-onset Alzheimer's disease and a reduced survival. Ann Neurol 1995; 37: 605-10.
17. Hardy J, Crook R, Perry R, Raghavan R, Roberts G. ApoE genotype and Down's syndrome. Lancet 1994; 343: 979-80.
18. Royston MC, Mann D, Pickering-Brown S, et al. Apolipoprotein E ∈2 allele promotes longevity and protects patients with Down's syndrome from dementia. Neuroreport 1994; 5: 2583-85.
19. Schupf N, Kapell D, Lee JH, Ottman R, Mayeux R. Increased risk of Alzheimer's disease in mothers of adults with Down's syndrome. Lancet 1994; 344: 353-56.
20. Emanuel I, Sever LE, Milham S Jr, Thuline HC. Accelerated ageing in young mothers of children with Down's syndrome. Lancet 1972; ii: 361-63.
21. Brook JD, Gosden RG, Chandley AC. Maternal ageing and aneuploid embryos - evidence from the mouse that biological and not chronological age is the important influence. Hum Genet 1984; 66: 41-45.
22. Mikkelsen M, Hallberg A, Poulsen H, Frantzen M, Hansen J, Petersen MB. Epidemiological study of Down's syndrome in Denmark, including family studies of chromosomes and DNA markers. Dev Brain Dysfunct 1995; 8: 4-12.
23. Sherman SL, Petersen MB, Freeman SB, et al. Non-disjunction of chromosome 21 in maternal meiosis I: evidence for a maternal age-dependent mechanism involving reduced recombination. Hum Molec Genet 1994; 3: 1529-35.
24. Gerdes LU, Klausen IC, Sihm I, Faergeman O. Apolipoprotein E polymorphism in a Danish population compared to findings in 45 other study populations around the world. Genet Epidemiol 1992; 9: 155-67.
25. Wenham PR, Price WH, Blundell G. Apolipoprotein E genotyping by one-stage PCR. Lancet 1991; 337: 1158-59.
26. Warren AC, Chakravarti A, Wong C, et al. Evidence for reduced recombination on the nondisjoined chromosomes 21 in Down syndrome. Science 1987; 237: 652-54.
27. Goate A, Chartier-Harlin M-C, Mullan M, et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 1991; 349: 704-06.
28. Levy-Lahad E, Wasco W, Poorkaj P, et al. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 1995; 269: 973-76.
29. Pericak-Vance MA, Bebout JL, Gaskell PC Jr, et al. Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage. Am J Hum Genet 1991; 48: 1034-50.
30. Strittmatter WJ, Weisgraber KH, Huang DY, et al. Binding of human apolipoprotein E to synthetic amyloid β peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proc Natl Acad Sci USA 1993; 90: 8098-102.
31. Hyman BT, West HL, Rebeck GW, et al. Quantitative analysis of senile plaques in Alzheimer disease: observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome). Proc Natl Acad Sci USA 1995; 92: 3586-90.
32. Gaulden ME. Maternal age effect: the enigma of Down syndrome and other trisomic conditions. Mutation Res 1992; 296: 69-88.
33. Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 1988; 240: 622-30.
34. Strittmatter WJ, Saunders AM, Goedert M, et al. Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. Proc Natl Acad Sci USA 1994; 91: 11183-86.
35. Fisher JM, Harvey JF, Morton NE, Jacobs PA. Trisomy 18: studies of the parent and cell division of origin and the effect of aberrant recombination on nondisjunction. Am J Hum Genet 1995; 56: 669-75.
36. Schachter F, Faure-Delanef L, Guenot F, et al. Genetic associations with human longevity at the APOE and ACE loci. Nature Genet 1994; 6: 29-32.
37. Haddow JE, Palomaki GE, Knight GJ, et al. Prenatal screening for Down's syndrome with use of maternal serum markers. N Engl J Med 1992; 327: 588-93.