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IgM M-protein with antibody activity against gangliosides with disialosyl residue in sensory neuropathy binds to sensory neurons
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Oka N, Kusaka H, Kusunoki S, Tsuda H, Kaji R, Imai T, Akiguchi I, Kimuri J: IgM M-protein with antibody activity against gangliosides with disialosyl residue in sensory neuropathy binds to sensory neurons. Muscle Nerve 1996, 19:528-530.
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Kremer DM, Lopez PHH, Mizutamari RK, Kremer LJ, Bacile EA, Nores GA: Factors defining target specificity in antibody-mediated neuropathy: density-dependent binding of anti-GD1a polyclonal IgG from a neurological patient. J Neurosci Res 1997, 47:636-641.
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Tora M, Graus F, de Bolos C, Real FX: Cell surface expression of paraneoplastic encephalomyelitis/sensory neuronopathy-associated Hu antigens in small cell lung cancers and neuroblastomas. Neurol 1997, 48:735-741. The difficult problem of reconciling a role for antibodies in disease pathogenesis when targeted at nuclear or other intracellular epitopes is addressed.
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