A somatically mutated human antiganglioside IgM antibody that induces experimental neuropathy in mice is encoded by the variable region heavy chain gene, V1-18

Journal of Clinical Investigation

Volumn 97, Issue 5, 1996, Pages 1155-1164

  Willison, Hugh J ^a,c   O'Hanlon, Graham M ^a   Paterson, Gary ^a   Veitch, Jean ^a   Wilson, George ^a   Roberts, Mark ^b   Tang, Teresa ^b   Vincent, Angela ^b  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c SOUTHERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

autoimmunity; electrophysiology; monoclonal antibodies; neuromuscular junction; peripheral nerve diseases

Indexed keywords

CENTOXIN; GANGLIOSIDE ANTIBODY; GANGLIOSIDE GD 1B; GANGLIOSIDE GD3; GANGLIOSIDE GT 1B; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN M ANTIBODY; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR CLONING; MOUSE; NEUROMUSCULAR SYNAPSE; NONHUMAN; PATHOPHYSIOLOGY; PERIPHERAL NEUROPATHY; PHRENIC NERVE; PRIORITY JOURNAL; SOMATIC MUTATION;

EID: 0029983215     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118529     Document Type: Article

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