Chemoenzymatic synthesis of GM3, lewis x and sialyl lewis x oligosaccharides in 13C-enriched form

Tetrahedron Letters

Volumn 38, Issue 33, 1997, Pages 5861-5864

  Probert, Mark A ^a   Milton, Mark J ^a   Harris, Richard ^a   Schenkman, Sergio ^b   Brown, Jonathan M ^c   Romans, Steven W ^a   Field, Robert A ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c Martek Biosciences Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GANGLIOSIDE; NEURAMINIC ACID DERIVATIVE;

ARTICLE; CARBOHYDRATE SYNTHESIS; DRUG SYNTHESIS; ENZYME ACTIVITY; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; REACTION ANALYSIS;

EID: 0030859008     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01304-X     Document Type: Article

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5. For recent studies on the Sialyl Lewis x - E-Selectin complex see: Cooke, R.M. et al Biochemistry, 1994, 33, 10591. Scheffler, K. et al Angew Chem. Int. Ed. Engl., 1995, 34, 1841. Poppe, L. et al J. Am. Chem. Soc., 1997, 119, 1727.
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22. 21 glycosides have both been used in trans-sialidase-catalysed α-2,3-sialylation reactions; we find the PNP glycoside to be convenient to prepare on a gram scale.
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26. - = 845.8 (-ve ion mode).