Molecular analysis of katG gene mutations in strains of Mycobacterium tuberculosis complex from Africa

Antimicrobial Agents and Chemotherapy

Volumn 41, Issue 7, 1997, Pages 1601-1603

  Haas, Walter H ^a   Schilke, Kathrin ^a   Brand, Jeanette ^b   Amthor, Beate ^a   Weyer, Karin ^b   Fourie, P Bernard ^b   Bretzel, Gisela ^c   Sticht Groh, Veronica ^c   Bremer, Hans J ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b Klinikum der Ludwig Maximilians Universität München   (Germany)

^c SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ISONIAZID;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL MUTATION; CODON; GENE MUTATION; GENE SEQUENCE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

EID: 0030858480     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.7.1601     Document Type: Article

References (16)

1. Altamirano, M., J. Marostenmaki, A. Wong, M. FitzGerald, W. A. Black, and J. A. Smith. 1994. Mutations in the catalase-peroxidase gene from isoniazid-resistant Mycobacterium tuberculosis isolates. J. Infect. Dis. 169:1162-1165.
2. Cockerill, F. R., J. R. Uhl, Z. Temesgen, Y. Zhang, L. Stockman, G. D. Roberts, D. L. Williams, and B. C. Kline. 1995. Rapid identification of a point mutation of the M. tuberculosis catalase-peroxidase (katG) gene associated with isoniazid resistance. J. Infect. Dis. 171:240-245.
3. David, H. L., M.-T. Jahan, A. Jumin, J. Grandry, and E. H. Lehman. 1978. Numerical taxonomy analysis of Mycobacterium africanum. Int. J. Syst. Bacteriol. 28:464-472.
4. Haas, W. H., G. Bretzel, B. Amthor, K. Schilke, G. Krommes, S. Rüsch-Gerdes, V. Sticht-Groh, and H. J. Bremer. 1997. Comparison of DNA fingerprint patterns of isolates of Mycobacterium africanum from East and West Africa. J. Clin. Microbiol. 35:663-666.
5. Haas, W. H., W. R. Butler, C. L. Woodley, and J. T. Crawford. 1993. Mixed-linker polymerase chain reaction: a new method for rapid fingerprinting of isolates of the Mycobacterium tuberculosis complex. J. Clin. Microbiol. 31: 1293-1298.
6. Heym, B., P. M. Alzari, N. Honore, and S. T. Cole. 1995. Missense mutations in the catalase-peroxidase gene, kat G, are associated with isoniazid resistance in Mycobacterium tuberculosis. Mol. Microbiol. 15:235-245.
7. Heym, B., N. Honore, C. Truffot-Pernot, A. Banerjee, C. Schurra, W. R. Jacobs, J. D. A. van Embden, J. H. Grosset, and S. T. Cole. 1994. Implications of multidrug resistance for the future of short-course chemotherapy of tuberculosis: a molecular study. Lancet 344:293-297.
8. Musser, J. M. 1995. Antimicrobial agent resistance in mycobacteria: molecular genetic insights. Clin. Microbiol. Rev. 8:496-514.
9. Musser, J. M., V. Kapur, D. L. Williams, B. N. Kreiswirth, D. van Soolingen, and J. D. A. van Embdem. 1995. Characterisation of the catalase-peroxidase gene (katG) and inhA locus in isoniazid-resistant and -susceptible strains of Mycobacterium tuberculosis by automated sequencing: restricted array of mutations associated with drug resistance. J. Infect Dis. 173:196-202.
10. Rouse, D. A., Z. Li, G.-H. Bai, and S. L. Morris. 1995. Characterization of the katG and inhA genes of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 39:2472-2476.
11. Sherman, D. R., K. Mdluli, M. J. Hickey, T. M. Arain, S. L. Morris, C. E. Barry, and C. K. Stover. 1996. Compensatory ahpC gene expression in isoniazid-resistant Mycobacterium tuberculosis. Science 272:1641-1643.
12. Sreevatsan, S., The International Working Group, and J. M. Musser. 1996. Molecular population genetics of katG codon 463 and gyrA codon 95 polymorphisms in the Mycobacterium tuberculosis complex, abstr. U-119, p. 122. In Abstracts of the 96th General Meeting of the American Society for Microbiology 1996. American Society for Microbiology, Washington, D.C.
13. Telenti, A., P. Imboden, F. Marchesi, T. Schmidheini, and T. Bodmer. 1993. Direct, automated detection of rifampin-resistant Mycobacterium tuberculosis by polymerase chain reaction and single-strand conformation polymorphism analysis. Antimicrob. Agents Chemother. 37:2054-2058.
14. Victor, T. C., G. S. Pretorius, J. V. Felix, A. M. Jordaan, P. D. van Helden, and K. D. Eisenach. 1996. katG mutations in isoniazid-resistant strains of Mycobacterium tuberculosis are not infrequent. Antimicrob. Agents Chemother. 40:1572. (Letter.)
15. Weyer, K., and H. H. Kleeberg. 1992. Primary and acquired drug resistance in adult black patients with tuberculosis in South Africa: results of a continuous national drug resistance surveillance programme involvement. Tubercle Lung Dis. 73:106-112.
16. Zhang, Y., B. Heym, B. Allen, D. Young, and S. Cole. 1992. The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis. Nature 358:591-593.